How far is Desoto Lakes, FL from Port Saint Lucie, FL?
The driving distance from Desoto Lakes, FL to Port Saint Lucie, FL is about 151.9 miles (244.5 km), with a travel time of about 02h 47m by car.
- The straight-line flight distance is about 131.4 miles (211.5 km).
- For a round trip, plan for roughly 05h 35m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM EDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 02h 47m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Sunny
Driving Route Map
The map below follows the saved road route between Desoto Lakes and Port Saint Lucie.
Turn-by-Turn Driving Directions
Step-by-step road directions between Desoto Lakes and Port Saint Lucie.
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1
Start on 42nd Street
1594 ft · 1 min · 42nd Street
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2
Turn left onto Hauri Road
1287 ft · 59 sec · Hauri Road
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3
Turn right onto 47th Street
54 m · 13 sec · 47th Street
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4
Turn left onto Habana Drive
1534 ft · 1 min · Habana Drive
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5
Turn right onto Tampico Drive
69 m · 14 sec · Tampico Drive
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6
Turn left onto San Jose Drive
1432 ft · 1 min · San Jose Drive
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7
At the end of the road, turn right onto DeSoto Road
1591 ft · 42 sec · DeSoto Road
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8
Continue on Longwood Run Boulevard
1.1 km · 2 min · Longwood Run Boulevard
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9
Turn right onto University Parkway
1.6 mi · 3 min · University Parkway
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10
Take the ramp slight right toward I 75 South: Naples
1 km · 1 min
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11
Merge slight left
7.2 mi · 8 min
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12
Take the exit slight right toward FL 72: Siesta Key, Arcadia
2533 ft · 1 min
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13
Keep slight left to continue on FL 72 East
122 m · 12 sec
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14
Turn straight onto Clark Road
1.8 mi · 3 min · Clark Road
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15
Enter the roundabout and take exit 2 toward Clark Road
30 m · 2 sec · Clark Road
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16
Exit the roundabout onto Clark Road
156 m · 10 sec · Clark Road
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17
Continue on State Road 72
1.3 mi · 2 min · State Road 72
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18
Enter the roundabout and take exit 2 toward State Road 72
26 m · 2 sec · State Road 72
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19
Exit the roundabout onto State Road 72
33.6 mi · 44 min · State Road 72
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20
At the end of the road, turn right
1.1 mi · 2 min
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21
Turn straight
89.8 mi · 1 hr 57 min
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22
Turn right onto West Midway Road
4.4 mi · 8 min · West Midway Road
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23
Take the ramp slight right toward I 95 South: West Palm Beach
2661 ft · 1 min
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24
Merge slight left
4.9 mi · 5 min
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25
Take the exit slight right toward Crosstown Parkway
1872 ft · 49 sec
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26
Turn left onto Crosstown Parkway
4.3 mi · 8 min · Crosstown Parkway
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27
Turn right onto Southeast Airoso Boulevard
916 ft · 21 sec · Southeast Airoso Boulevard
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28
Turn right onto Southwest Carter Avenue
66 m · 9 sec · Southwest Carter Avenue
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29
Arrive at your destination
0 m · 1 sec · Southwest Carter Avenue
Car Route Details
A richer read on the saved driving route between Desoto Lakes and Port Saint Lucie.
Interchange-aware route
The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.
Longest stretch
Turn straight
89.8 mi · 01h 57m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Sunny leaving Desoto Lakes and Sunny near Port Saint Lucie.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Desoto Lakes to Port Saint Lucie?
The road trip is about 151.9 miles (244.5 km) and usually takes 02h 47m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Placid Lakes is a useful midpoint, sitting about 77.2 miles from Desoto Lakes and 74.8 miles from Port Saint Lucie.
How much longer is the road route than the straight-line distance?
The direct path is about 131.4 miles (211.5 km), while the road route adds roughly 20.5 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM EDT. If you want a more comfortable same-day return, try to leave by 12:54 PM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $22.23 one way or $44.47 round trip. Estimated CO2 is about 47.6 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Desoto Lakes and Sunny near Port Saint Lucie.
Stop Ideas Near Placid Lakes
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Placid Lakes.
Sebring
Okeechobee
Port Charlotte, Florida
Fort Myers, Florida
Flight Path Map
This map shows the direct air route between Desoto Lakes and Port Saint Lucie. Straight-line distance: 131.43 mi (211.51 km).
#1 Desoto Lakes
Census-designated place in Sarasota County, Florida
| Population | 3,646 |
| Coordinates | 27.3714300, -82.4898200 |
| Altitude | 9 |
| Country | United States |
#2 Port Saint Lucie
The second most populous city in St.
| Population | 209,715 |
| Coordinates | 27.2939300, -80.3503300 |
| Altitude | 5 |
| Country | United States |
End: Southwest Carter Avenue (-80.350328, 27.294381)
Estimated Travel Time
Distance: 245 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 05h 03m |
| 40 mph (64.37 km/h) | 03h 47m |
| 50 mph (80.47 km/h) | 03h 02m |
| 60 mph (96.56 km/h) | 02h 31m |
| 70 mph (112.65 km/h) | 02h 10m |
| 80 mph (129 km/h) | 01h 53m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.15 | $22.23 | $44.47 |
| Mid-grade | $4.60 | $24.63 | $49.27 |
| Premium | $4.90 | $26.24 | $52.49 |
| Diesel | $4.35 | $23.32 | $46.63 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Florida · Apr 19, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.