How far is Depew, NY from Syracuse, NY?
The driving distance from Depew, NY to Syracuse, NY is about 141.9 miles (228.4 km), with a travel time of about 02h 16m by car.
- The straight-line flight distance is about 129 miles (207.6 km).
- For a round trip, plan for roughly 04h 32m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM EDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 02h 16m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Village in Ontario County, New York
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Driving Route Map
The map below follows the saved road route between Depew and Syracuse.
Turn-by-Turn Driving Directions
Step-by-step road directions between Depew and Syracuse.
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1
Start on Terrace Boulevard
72 m · 7 sec · Terrace Boulevard
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2
Turn slight right onto Westfield Avenue
1095 ft · 37 sec · Westfield Avenue
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3
At the end of the road, turn left onto Gould Avenue
54 m · 7 sec · Gould Avenue
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4
Turn right onto Transit Road
2.9 mi · 6 min · Transit Road
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5
Take the exit left
1096 ft · 27 sec
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6
Continue straight
978 ft · 24 sec
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7
Keep slight right to continue on I 90 East: Albany
1593 ft · 39 sec
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8
Merge slight left onto New York State Thruway
127.4 mi · 2 hr 27 min · New York State Thruway
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9
Take the exit slight right toward I 690, NY 690: Syracuse, Fulton
1.1 km · 1 min
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10
Keep slight right to continue on I 690 East: Fairgrounds, Syracuse
1225 ft · 30 sec
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11
Continue straight
7.9 mi · 10 min
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12
Take the exit slight right toward Downtown
636 ft · 16 sec
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13
Keep slight right to continue on Downtown
833 ft · 27 sec
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14
Turn left onto West Genesee Street
1939 ft · 1 min · West Genesee Street
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15
Continue on James Street
607 ft · 23 sec · James Street
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16
Turn right onto Oswego Boulevard
97 m · 12 sec · Oswego Boulevard
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17
Continue on Erie Boulevard East
160 m · 19 sec · Erie Boulevard East
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18
Turn right onto South State Street
989 ft · 25 sec · South State Street
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19
Arrive at your destination
0 m · 1 sec · South State Street
Car Route Details
A richer read on the saved driving route between Depew and Syracuse.
Straightforward drive
The saved road route has a manageable number of maneuvers and should be easy to follow with normal attention to signs.
New York State Thruway
Merge slight left onto New York State Thruway
127 mi · 02h 27m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Mostly Sunny leaving Depew and Mostly Sunny near Syracuse.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Depew to Syracuse?
The road trip is about 141.9 miles (228.4 km) and usually takes 02h 16m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Victor is a useful midpoint, sitting about 70.4 miles from Depew and 71.5 miles from Syracuse.
How much longer is the road route than the straight-line distance?
The direct path is about 129 miles (207.6 km), while the road route adds roughly 12.9 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM EDT. If you want a more comfortable same-day return, try to leave by 1:58 PM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $20.09 one way or $40.17 round trip. Estimated CO2 is about 44.5 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around Depew and Mostly Sunny near Syracuse.
Stop Ideas Near Victor
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Victor.
Louise M. Slaughter Rochester Station
Empire Expo Center
William F. Walsh Regional Transportation Center
Buffalo–Depew station
Flight Path Map
This map shows the direct air route between Depew and Syracuse. Straight-line distance: 129.03 mi (207.65 km).
#1 Depew
City in Creek County, Oklahoma, United States of America
| Population | 14,940 |
| Coordinates | 42.9039500, -78.6922500 |
| Altitude | 205 |
| Country | United States |
#2 Syracuse
The fifth most populous city in New York.
| Population | 141,229 |
| Coordinates | 43.0481200, -76.1474200 |
| Altitude | 121 |
| Country | United States |
End: South State Street (-76.14744, 43.04812)
Estimated Travel Time
Distance: 228 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 04h 43m |
| 40 mph (64.37 km/h) | 03h 32m |
| 50 mph (80.47 km/h) | 02h 50m |
| 60 mph (96.56 km/h) | 02h 21m |
| 70 mph (112.65 km/h) | 02h 01m |
| 80 mph (129 km/h) | 01h 46m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.01 | $20.09 | $40.17 |
| Mid-grade | $4.48 | $22.45 | $44.90 |
| Premium | $4.86 | $24.35 | $48.71 |
| Diesel | $4.69 | $23.52 | $47.03 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in New York · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.