How far is Depew, NY from Islip, NY?
The driving distance from Depew, NY to Islip, NY is about 418.4 miles (673.3 km), with a travel time of about 07h 07m by car.
- The straight-line flight distance is about 319.7 miles (514.5 km).
- For a round trip, plan for roughly 14h 14m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 07h 07m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Steuben County, New York, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Driving Route Map
The map below follows the saved road route between Depew and Islip.
Turn-by-Turn Driving Directions
Step-by-step road directions between Depew and Islip.
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1
Start on Terrace Boulevard
67 m · 6 sec · Terrace Boulevard
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2
Turn slight right onto Bloomfield Avenue
1352 ft · 41 sec · Bloomfield Avenue
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3
Turn slight left onto Broadway
25.6 mi · 41 min · Broadway
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4
Continue on Telephone Road
6.5 mi · 9 min · Telephone Road
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5
Turn right onto Ellicott Street Road
3 mi · 5 min · Ellicott Street Road
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6
Continue on Big Tree Road
4.1 mi · 6 min · Big Tree Road
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7
Continue on State Highway 63
1.1 km · 55 sec · State Highway 63
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8
Continue on Genesee Street
7.5 mi · 11 min · Genesee Street
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9
Enter the roundabout and take exit 1 toward Genesee Street
33 m · 2 sec · Genesee Street
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10
Exit the roundabout onto Genesee Street
1.3 mi · 2 min · Genesee Street
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11
Merge slight left onto Geneseo-Mount Morris Road
3.3 mi · 4 min · Geneseo-Mount Morris Road
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12
Continue on Mount Morris-Geneseo Road
1615 ft · 32 sec · Mount Morris-Geneseo Road
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13
Take the ramp left
2173 ft · 53 sec
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14
Merge slight left onto Genesee Expressway
38.2 mi · 44 min · Genesee Expressway
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15
Merge slight right onto Southern Tier Expressway
104.5 mi · 2 hr 2 min · Southern Tier Expressway
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16
Keep slight right to continue on I 81 South: Scranton
53.4 mi · 1 hr 3 min
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17
Keep slight right to continue on I 84 East, I 380 South, US 6 East: Carbondale, Mt Pocono
1.2 km · 1 min
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18
Continue on I 84 East, I 380 South: Mount Pocono, Milford
3.7 mi · 5 min
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19
Keep slight right to continue on I 380 South: Mount Pocono
23.6 mi · 26 min
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20
Keep slight left to continue on I 80 East: Stroudsburg
1 mi · 1 min
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21
Merge slight right onto Keystone Shortway
80 mi · 1 hr 37 min · Keystone Shortway
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22
Keep slight right to continue on Christopher Columbus Highway
5.5 mi · 6 min · Christopher Columbus Highway
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23
Keep slight left to continue on I 95 North: George Washington Bridge, New York City
1503 ft · 23 sec
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24
Keep slight right to continue on Leonia, Teaneck
2128 ft · 38 sec
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25
Turn right onto Leonia
1032 ft · 35 sec
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26
Turn straight onto Degraw Avenue
138 m · 9 sec · Degraw Avenue
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27
Continue on Fort Lee Road
1.1 mi · 2 min · Fort Lee Road
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28
Continue on Main Street
143 m · 13 sec · Main Street
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29
Take the ramp left toward George Washington Bridge
144 m · 13 sec
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30
Merge slight left onto Bergen Boulevard
1552 ft · 29 sec · Bergen Boulevard
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31
Take the exit slight left toward George Washington Bridge Upper Level
95 m · 5 sec
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32
Merge slight left
1649 ft · 20 sec
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33
Keep slight left
1.3 km · 1 min
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34
Continue on George Washington Bridge (upper level)
3174 ft · 1 min · George Washington Bridge (upper level)
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35
Continue on Trans-Manhattan Expressway
1.2 km · 1 min · Trans-Manhattan Expressway
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36
Continue on Cross Bronx Expressway
4.7 mi · 6 min · Cross Bronx Expressway
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37
Keep slight right to continue on Cross Bronx Expressway
2 mi · 3 min · Cross Bronx Expressway
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38
Merge slight left onto Throgs Neck Expressway
3271 ft · 58 sec · Throgs Neck Expressway
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39
Continue on Throgs Neck Bridge
2 mi · 3 min · Throgs Neck Bridge
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40
Continue on Clearview Expressway
5 mi · 5 min · Clearview Expressway
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41
Continue on Hollis Court Boulevard
1.2 km · 1 min · Hollis Court Boulevard
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42
At the end of the road, turn left onto Jamaica Avenue
1117 ft · 35 sec · Jamaica Avenue
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43
Turn right onto Hempstead Avenue
1.4 km · 2 min · Hempstead Avenue
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44
Turn right onto 225th Street
69 m · 10 sec · 225th Street
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45
Take the ramp straight toward Cross Island Parkway South, Verrazano Bridge
1171 ft · 29 sec
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46
Merge slight left onto Cross Island Parkway
1.3 mi · 2 min · Cross Island Parkway
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47
Take the exit slight left toward Southern State Parkway East, Eastern Long Island
2383 ft · 1 min
-
48
Merge slight left onto Southern State Parkway
24.5 mi · 31 min · Southern State Parkway
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49
Keep slight left to continue on Southern State Parkway
1072 ft · 16 sec · Southern State Parkway
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50
Take the exit slight right toward Bay Shore Road South, Bay Shore
1044 ft · 32 sec
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51
Turn straight onto Bay Shore Road
2667 ft · 1 min · Bay Shore Road
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52
Continue on Howells Road
1845 ft · 44 sec · Howells Road
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53
Turn straight onto Sunrise Highway
104 m · 7 sec · Sunrise Highway
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54
Keep slight right to continue on Howells Road
3115 ft · 2 min · Howells Road
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55
Continue on Roosevelt Street
1248 ft · 25 sec · Roosevelt Street
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56
Continue on 3rd Avenue
1 km · 1 min · 3rd Avenue
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57
At the end of the road, turn left onto East Main Street
1.1 mi · 2 min · East Main Street
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58
Continue on Montauk Highway
1014 ft · 17 sec · Montauk Highway
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59
Continue on Main Street
1.2 km · 1 min · Main Street
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60
Arrive at your destination
0 m · 1 sec · Main Street
Car Route Details
A richer read on the saved driving route between Depew and Islip.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Southern Tier Expressway
Merge slight right onto Southern Tier Expressway
105 mi · 02h 02m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Mostly Sunny near Depew.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Depew to Islip?
The road trip is about 418.4 miles (673.3 km) and usually takes 07h 07m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Riverside is a useful midpoint, sitting about 207.8 miles from Depew and 210.6 miles from Islip.
How much longer is the road route than the straight-line distance?
The direct path is about 319.7 miles (514.5 km), while the road route adds roughly 98.7 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM EDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $59.17 one way or $118.35 round trip. Estimated CO2 is about 131.2 kg one way.
What should you check before leaving?
Before leaving, the latest forecast around Depew is Mostly Sunny.
Stop Ideas Near Riverside
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Riverside.
Scranton, PA
Wilkes-Barre, PA
White Haven, PA
Flight Path Map
This map shows the direct air route between Depew and Islip. Straight-line distance: 319.67 mi (514.46 km).
#1 Depew
City in Creek County, Oklahoma, United States of America
| Population | 14,940 |
| Coordinates | 42.9039500, -78.6922500 |
| Altitude | 205 |
| Country | United States |
#2 Islip
This Long Island community is situated on the south shore of Suffolk County, New York, at an elevation of 13 feet.
| Population | 322,328 |
| Coordinates | 40.7298200, -73.2103900 |
| Altitude | 4 |
| Country | United States |
End: Main Street (-73.210382, 40.729789)
Estimated Travel Time
Distance: 673 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 13h 56m |
| 40 mph (64.37 km/h) | 10h 27m |
| 50 mph (80.47 km/h) | 08h 22m |
| 60 mph (96.56 km/h) | 06h 58m |
| 70 mph (112.65 km/h) | 05h 58m |
| 80 mph (129 km/h) | 05h 13m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.01 | $59.17 | $118.35 |
| Mid-grade | $4.48 | $66.14 | $132.28 |
| Premium | $4.86 | $71.75 | $143.50 |
| Diesel | $4.69 | $69.28 | $138.57 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in New York · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.