How far is Columbia, MO from De Soto, MO?
The driving distance from Columbia, MO to De Soto, MO is about 149.5 miles (240.6 km), with a travel time of about 03h 06m by car.
- The straight-line flight distance is about 111.3 miles (179.1 km).
- For a round trip, plan for roughly 06h 12m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 06m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
This departure sits inside the recommended comfort window for the route.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Missouri USA
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Showers And Thunderstorms
Chance Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Columbia and De Soto.
Turn-by-Turn Driving Directions
Step-by-step road directions between Columbia and De Soto.
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1
Start on North Providence Road
1.2 mi · 3 min · North Providence Road
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2
Take the ramp slight right toward I 70 East, US 40 East: Saint Louis
879 ft · 22 sec
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3
Merge slight left onto Highway Patrol Sgt. Benjamin Booth Memorial Highway
2467 ft · 35 sec · Highway Patrol Sgt. Benjamin Booth Memorial Highway
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4
Continue on Sheriff Roger I. Wilson Memorial Highway
1.9 mi · 2 min · Sheriff Roger I. Wilson Memorial Highway
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5
Continue on Dwight D. Eisenhower Highway
81 mi · 1 hr 35 min · Dwight D. Eisenhower Highway
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6
Take the exit slight right toward I 64 East, US 40 East, US 61 South: Chesterfield
1567 ft · 33 sec
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7
Merge slight left onto Avenue of the Saints
22 mi · 27 min · Avenue of the Saints
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8
Take the exit slight right toward MO 141
1368 ft · 34 sec
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9
Turn right onto MO 141: Manchester
56 m · 6 sec
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10
Merge slight left
11 mi · 17 min
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11
Keep slight left
4 mi · 6 min
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12
Take the exit slight right toward MO 21 South: Hillsboro
1043 ft · 14 sec
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13
Merge slight left onto Veterans Memorial Highway
19.8 mi · 23 min · Veterans Memorial Highway
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14
At the end of the road, turn left
2501 ft · 49 sec
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15
Continue straight
3.9 mi · 5 min
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16
Turn left
1.5 mi · 2 min
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17
Turn right onto North Main Street
1.4 mi · 2 min · North Main Street
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18
Turn right onto Easton Street
133 m · 19 sec · Easton Street
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19
Arrive at your destination
0 m · 1 sec · Easton Street
Car Route Details
A richer read on the saved driving route between Columbia and De Soto.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Dwight D. Eisenhower Highway
Continue on Dwight D. Eisenhower Highway
81 mi · 01h 35m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Chance Showers And Thunderstorms leaving Columbia and Chance Showers And Thunderstorms near De Soto.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Columbia to De Soto?
The road trip is about 149.5 miles (240.6 km) and usually takes 03h 06m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Wright City is a useful midpoint, sitting about 74.7 miles from Columbia and 74.8 miles from De Soto.
How much longer is the road route than the straight-line distance?
The direct path is about 111.3 miles (179.1 km), while the road route adds roughly 38.2 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 10:48 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $19.91 one way or $39.82 round trip. Estimated CO2 is about 46.9 kg one way.
What should you check before leaving?
Before you leave, expect Chance Showers And Thunderstorms around Columbia and Chance Showers And Thunderstorms near De Soto.
Stop Ideas Near Wright City
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
City Hall Park
Warrenton City Animal Control
Moscow Mills City Hall
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Wright City.
Washington
Hermann
Kirkwood
Gateway Transportation Center
Flight Path Map
This map shows the direct air route between Columbia and De Soto. Straight-line distance: 111.31 mi (179.14 km).
#1 Columbia
The most populous city in the state of Missouri.
| Population | 124,769 |
| Coordinates | 38.9517100, -92.3340700 |
| Altitude | 215 |
| Country | United States |
#2 De Soto
City in Jefferson County, Missouri
| Population | 6,340 |
| Coordinates | 38.1395000, -90.5551300 |
| Altitude | 160 |
| Country | United States |
End: De Soto (-90.55513, 38.1395)
Estimated Travel Time
Distance: 241 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 04h 58m |
| 40 mph (64.37 km/h) | 03h 44m |
| 50 mph (80.47 km/h) | 02h 59m |
| 60 mph (96.56 km/h) | 02h 29m |
| 70 mph (112.65 km/h) | 02h 08m |
| 80 mph (129 km/h) | 01h 51m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $19.91 | $39.82 |
| Mid-grade | $4.25 | $22.46 | $44.91 |
| Premium | $4.65 | $24.57 | $49.15 |
| Diesel | $5.30 | $28.01 | $56.01 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · May 31, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.