How far is Columbia, MO from Cairo, 11?
The driving distance from Columbia, MO to Cairo, 11 is about 1631 miles (2624.9 km), with a travel time of about 32h 00m by car.
- The straight-line flight distance is about 6446.4 miles (10374.4 km).
- For a round trip, plan for roughly 64h 00m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 32h 00m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City of Pennsylvania
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Rain Showers
Driving Route Map
The map below follows the saved road route between Columbia and Cairo.
Turn-by-Turn Driving Directions
Step-by-step road directions between Columbia and Cairo.
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1
Start on North Providence Road
1.2 mi · 3 min · North Providence Road
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2
Take the ramp slight right toward I 70 East, US 40 East: Saint Louis
879 ft · 22 sec
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3
Merge slight left onto Highway Patrol Sgt. Benjamin Booth Memorial Highway
2467 ft · 35 sec · Highway Patrol Sgt. Benjamin Booth Memorial Highway
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4
Continue on Sheriff Roger I. Wilson Memorial Highway
1.9 mi · 2 min · Sheriff Roger I. Wilson Memorial Highway
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5
Continue on Dwight D. Eisenhower Highway
103.1 mi · 2 hr 3 min · Dwight D. Eisenhower Highway
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6
Take the exit slight right toward I 270: Chicago, Memphis
872 ft · 12 sec
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7
Keep slight left to continue on I 270 North: Chicago
2556 ft · 36 sec
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8
Continue on I 270 North: Chicago
1270 ft · 18 sec
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9
Keep slight left to continue on I 270 North: Chicago
988 ft · 14 sec
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10
Merge slight left
29.9 mi · 37 min
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11
Merge slight right onto I 70 East: Indianapolis
82.8 mi · 1 hr 29 min
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12
Keep slight right to continue on I 70 East: Indianapolis
140.1 mi · 2 hr 36 min
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13
Keep slight left
75.4 mi · 1 hr 29 min
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14
Keep slight left
24.2 mi · 26 min
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15
Keep slight left
20.9 mi · 24 min
-
16
Keep slight left
49.2 mi · 53 min
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17
Keep slight left to continue on I 670 East: Airport
4.3 mi · 5 min
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18
Keep slight right to continue on North Innerbelt
1003 ft · 16 sec · North Innerbelt
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19
Take the exit slight right toward I 71 North: Cleveland
2166 ft · 41 sec
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20
Keep slight left to continue on I 71 North: Cleveland
1560 ft · 38 sec
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21
Merge slight left
99.5 mi · 1 hr 48 min
-
22
Take the exit slight right toward I 76, US 224: Lodi, Akron
1162 ft · 28 sec
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23
Keep slight right to continue on I 76, US 224 East: Akron
1.5 km · 1 min
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24
Merge slight left
17.2 mi · 20 min
-
25
Keep slight right to continue on Kenmore Expressway
1.9 mi · 2 min · Kenmore Expressway
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26
Keep slight right to continue on I 76 East: Akron
1.2 mi · 2 min
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27
Keep slight left
39.2 mi · 44 min
-
28
Continue straight
4 mi · 5 min
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29
Keep slight left
272.8 mi · 4 hr 55 min
-
30
Take the exit slight left toward I 81 North: Wilkes-Barre
1.1 km · 1 min
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31
Merge slight left
34.7 mi · 42 min
-
32
Take the exit slight right toward I-84 east, US 6 east
2101 ft · 51 sec
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33
Keep slight left
1448 ft · 35 sec
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34
Keep slight right to continue on I 84 East, I 380 South: Mt Pocono, Milford
2050 ft · 39 sec
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35
Merge slight left
3.4 mi · 4 min
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36
Keep slight left to continue on I 84 East: Milford
129.1 mi · 2 hr 33 min
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37
Keep slight right to continue on Waterbury
42.7 mi · 51 min
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38
Keep slight right
14.2 mi · 19 min
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39
Keep slight left
2.3 mi · 3 min
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40
Keep slight left to continue on I 84 East: Boston
39.7 mi · 46 min
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41
Merge slight left onto Massachusetts Turnpike
27.4 mi · 32 min · Massachusetts Turnpike
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42
Take the exit slight right toward I 495: Portsmouth New Hampshire, Taunton
1119 ft · 38 sec
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43
Keep slight left to continue on I 495 North: Lowell, Portsmouth New Hampshire
1126 ft · 34 sec
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44
Keep slight left to continue on I 495 North: Lowell, Portsmouth NH
3219 ft · 1 min
-
45
Merge slight left
62.8 mi · 1 hr 13 min
-
46
Merge slight left
6.7 mi · 8 min
-
47
Keep slight left to continue on Blue Star Turnpike
7.8 mi · 9 min · Blue Star Turnpike
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48
Keep slight right to continue on Blue Star Turnpike
46.4 mi · 51 min · Blue Star Turnpike
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49
Keep slight right to continue on Downtown Portland
52.5 mi · 1 hr 1 min
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50
Merge slight left onto Maine Turnpike
9.8 mi · 11 min · Maine Turnpike
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51
Take the exit slight right toward ME 3: Augusta, Belfast
767 ft · 26 sec
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52
Keep slight right
834 ft · 20 sec
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53
Merge slight left onto Augusta Bypass
2.5 mi · 4 min · Augusta Bypass
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54
Continue on North Belfast Avenue
8.1 mi · 12 min · North Belfast Avenue
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55
Continue on Belfast Road
1077 ft · 17 sec · Belfast Road
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56
Continue on Route 3
17.6 mi · 21 min · Route 3
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57
Continue on Acadia Highway
4 mi · 4 min · Acadia Highway
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58
Continue on Belfast Augusta Road West
3.4 mi · 4 min · Belfast Augusta Road West
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59
Continue on Augusta Road
4.8 mi · 5 min · Augusta Road
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60
Continue on Belmont Avenue
4 mi · 5 min · Belmont Avenue
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61
Take the exit left
1586 ft · 44 sec
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62
Merge slight left onto Route 1
1.1 km · 1 min · Route 1
-
63
Continue on Searsport Avenue
2.7 mi · 5 min · Searsport Avenue
-
64
Continue on West Main Street
7 mi · 8 min · West Main Street
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65
Keep slight right to continue on East Main Street
6.3 mi · 8 min · East Main Street
-
66
Continue on US Highway 1
1.2 mi · 3 min · US Highway 1
-
67
Continue on Route 1
155 m · 12 sec · Route 1
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68
Continue on Route 1
1 mi · 1 min · Route 1
-
69
Continue on Acadia Highway
9.4 mi · 11 min · Acadia Highway
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70
Continue on Bucksport Road
8.5 mi · 10 min · Bucksport Road
-
71
Continue on West Main Street
1116 ft · 17 sec · West Main Street
-
72
Turn right onto Water Street
1.1 km · 1 min · Water Street
-
73
Turn left onto Foster Street
2227 ft · 1 min · Foster Street
-
74
Turn right onto High Street
1615 ft · 43 sec · High Street
-
75
Turn left
30.6 mi · 46 min
-
76
Turn right onto Bridge Street
1721 ft · 29 sec · Bridge Street
-
77
Continue on Kennedy Highway
4.1 mi · 6 min · Kennedy Highway
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78
Continue on US Highway 1A
3 mi · 5 min · US Highway 1A
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79
Continue on Kennedy Highway
1084 ft · 18 sec · Kennedy Highway
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80
Continue on Main Street
2784 ft · 47 sec · Main Street
-
81
Continue on Route 1
14 mi · 21 min · Route 1
-
82
Continue on Harrington Road
3.3 mi · 5 min · Harrington Road
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83
Continue on Outer Dublin Street
1249 ft · 21 sec · Outer Dublin Street
-
84
Continue on Dublin Street
2.3 mi · 3 min · Dublin Street
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85
Continue on Main Street
4.3 mi · 6 min · Main Street
-
86
Turn slight left onto Main Street
3.1 mi · 5 min · Main Street
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87
Continue on Route 1
9.5 mi · 13 min · Route 1
-
88
Turn right onto Lubec Road
1 km · 2 min · Lubec Road
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89
Continue on County Road
9.3 mi · 14 min · County Road
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90
Continue on Main Street
1.3 km · 2 min · Main Street
-
91
Turn right onto Washington Street
1900 ft · 38 sec · Washington Street
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92
Continue on State Route 189
154 m · 10 sec · State Route 189
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93
Continue on FDR International Memorial Bridge
880 ft · 18 sec · FDR International Memorial Bridge
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94
Continue straight
130 m · 8 sec
-
95
Keep slight left to continue on Route 774
1.5 mi · 3 min · Route 774
-
96
Turn right onto Glen Severn Road
1.7 mi · 7 min · Glen Severn Road
-
97
Turn right onto Liberty Point Drive
2409 ft · 3 min · Liberty Point Drive
-
98
Keep slight left
993 ft · 1 min
-
99
Turn straight onto Liberty Point Drive
1.6 mi · 10 min · Liberty Point Drive
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100
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between Columbia and Cairo.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
I 76 East
Keep slight left
273 mi · 04h 55m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Chance Rain Showers near Columbia.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Columbia to Cairo?
The road trip is about 1631 miles (2624.9 km) and usually takes 32h 00m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
DuBois is a useful midpoint, sitting about 800.3 miles from Columbia and 830.7 miles from Cairo.
How much longer is the road route than the straight-line distance?
The direct path is about 6446.4 miles (10374.4 km), while the road route adds roughly 0 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM CDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $241.42 one way or $482.84 round trip. Estimated CO2 is about 511.4 kg one way.
Do you cross a time zone on this route?
Yes. There is about a 8 hour time difference between Columbia and Cairo, so arrival and return times should be read in local time.
What should you check before leaving?
Before leaving, the latest forecast around Columbia is Chance Rain Showers.
Stop Ideas Near DuBois
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to DuBois.
Tyrone
Altoona Transportation Center
Johnstown
Huntingdon
Flight Path Map
This map shows the direct air route between Columbia and Cairo. Straight-line distance: 6446.35 mi (10374.4 km).
#1 Columbia
The most populous city in the state of Missouri.
| Population | 124,769 |
| Coordinates | 38.9517100, -92.3340700 |
| Altitude | 215 |
| Country | United States |
End: Cairo (31.25, 30.05)
Estimated Travel Time
Distance: 2625 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 54h 20m |
| 40 mph (64.37 km/h) | 40h 46m |
| 50 mph (80.47 km/h) | 32h 37m |
| 60 mph (96.56 km/h) | 27h 11m |
| 70 mph (112.65 km/h) | 23h 18m |
| 80 mph (129 km/h) | 20h 20m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.20 | $241.42 | $482.84 |
| Mid-grade | $4.56 | $262.49 | $524.97 |
| Premium | $4.92 | $283.15 | $566.29 |
| Diesel | $6.31 | $363.14 | $726.28 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Sep 26, 2026