How far is Chillicothe, OH from Chicago, IL?
The driving distance from Chillicothe, OH to Chicago, IL is about 366.9 miles (590.4 km), with a travel time of about 07h 07m by car.
- The straight-line flight distance is about 300.3 miles (483.3 km).
- For a round trip, plan for roughly 14h 15m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 07h 07m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
A city in Marion County, Indiana.
Route Weather Snapshot
Check the forecast at both ends before you head out.
Driving Route Map
The map below follows the saved road route between Chillicothe and Chicago.
Turn-by-Turn Driving Directions
Step-by-step road directions between Chillicothe and Chicago.
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1
Start on West Main Street
1683 ft · 30 sec · West Main Street
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2
Turn right onto North High Street
1.5 mi · 2 min · North High Street
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3
Take the ramp left toward US 35 West: Dayton
1035 ft · 25 sec
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4
Merge slight left
73.9 mi · 1 hr 23 min
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5
Take the exit slight right toward SR 48: Main Street, Jefferson Street
3027 ft · 1 min
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6
Keep slight right to continue on Jefferson Street, Day Air Ballpark, Patterson boulevard
98 m · 8 sec
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7
Turn slight right onto South Jefferson Street
1.2 km · 1 min · South Jefferson Street
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8
At the end of the road, turn left onto East Monument Avenue
1.1 km · 1 min · East Monument Avenue
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9
Turn left onto West Riverview Avenue
677 ft · 18 sec · West Riverview Avenue
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10
Turn right onto Salem Avenue
101.9 mi · 1 hr 59 min · Salem Avenue
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11
Take the exit slight right toward I 465 South, I 465 North
1463 ft · 26 sec
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12
Keep slight right to continue on I 465 North
2479 ft · 54 sec
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13
Merge slight right
6.1 mi · 7 min
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14
Keep slight left
1477 ft · 20 sec
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15
Continue on I-465 WB
1.3 km · 57 sec · I-465 WB
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16
Continue straight
10.9 mi · 13 min
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17
Keep slight left to continue on I 865 West: Chicago
5 mi · 6 min
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18
Merge slight left
12.3 mi · 13 min
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19
Take the exit slight right toward US 52 West
1281 ft · 16 sec
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20
Keep slight left
786 ft · 10 sec
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21
Merge slight left
120.1 mi · 2 hr 12 min
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22
Turn left onto East 5th Avenue
1.5 km · 2 min · East 5th Avenue
-
23
Continue on East 4th Avenue
1.1 km · 1 min · East 4th Avenue
-
24
Turn right onto Broadway
154 m · 22 sec · Broadway
-
25
Turn left onto I 90 West
1482 ft · 38 sec
-
26
Merge slight left onto Indiana Toll Road
13.1 mi · 14 min · Indiana Toll Road
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27
Turn straight onto Indiana Toll Road
963 ft · 2 min · Indiana Toll Road
-
28
Merge slight right onto Indiana Toll Road
1.6 km · 2 min · Indiana Toll Road
-
29
Continue on Chicago Skyway
2.9 mi · 5 min · Chicago Skyway
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30
Turn straight onto Chicago Skyway
724 ft · 18 sec · Chicago Skyway
-
31
Merge slight left onto Chicago Skyway
4.1 mi · 6 min · Chicago Skyway
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32
Keep slight left to continue on Chicago Skyway
1987 ft · 31 sec · Chicago Skyway
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33
Merge slight left onto Dan Ryan Expressway (Express)
5.5 mi · 8 min · Dan Ryan Expressway (Express)
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34
Take the exit slight right toward Canalport Avenue, Cermak Road
1620 ft · 40 sec
-
35
Turn slight left onto South Ruble Street
74 m · 7 sec · South Ruble Street
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36
Turn slight left
23 m · 5 sec
-
37
Turn left onto South Canalport Avenue
887 ft · 26 sec · South Canalport Avenue
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38
Turn left onto South Halsted Street
737 ft · 19 sec · South Halsted Street
-
39
Turn right onto West Cermak Road
976 ft · 25 sec · West Cermak Road
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40
Turn left
46 m · 11 sec
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41
Turn right
794 ft · 58 sec
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42
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between Chillicothe and Chicago.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
US 52 West
Merge slight left
120 mi · 02h 12m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Partly Sunny leaving Chillicothe and Sunny near Chicago.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Chillicothe to Chicago?
The road trip is about 366.9 miles (590.4 km) and usually takes 07h 07m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Lawrence is a useful midpoint, sitting about 183.3 miles from Chillicothe and 183.6 miles from Chicago.
How much longer is the road route than the straight-line distance?
The direct path is about 300.3 miles (483.3 km), while the road route adds roughly 66.6 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM EDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $47.94 one way or $95.89 round trip. Estimated CO2 is about 115 kg one way.
Do you cross a time zone on this route?
Yes. There is about a 1 hour time difference between Chillicothe and Chicago, so arrival and return times should be read in local time.
What should you check before leaving?
Before you leave, expect Partly Sunny around Chillicothe and Sunny near Chicago.
Stop Ideas Near Lawrence
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Noblesville Housing Authority
Carmel City Hall
Thomas A. Weaver Municipal Complex
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Lawrence.
Indianapolis Union Station
Crawfordsville
Connersville station
Crawfordsville (Bus), Indiana
Flight Path Map
This map shows the direct air route between Chillicothe and Chicago. Straight-line distance: 300.28 mi (483.26 km).
#1 Chillicothe
City in and the county seat of Ross County, Ohio, United States
| Population | 21,647 |
| Coordinates | 39.3331200, -82.9824000 |
| Altitude | 192 |
| Country | United States |
#2 Chicago
The third most populous city in the United States and the center of the Chicago metropolitan area.
| Population | 2,677,643 |
| Coordinates | 41.850033, -87.6500523 |
| Altitude | 179 |
| Country | United States |
End: Chicago (-87.650052, 41.850033)
Estimated Travel Time
Distance: 590 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 12h 13m |
| 40 mph (64.37 km/h) | 09h 10m |
| 50 mph (80.47 km/h) | 07h 20m |
| 60 mph (96.56 km/h) | 06h 06m |
| 70 mph (112.65 km/h) | 05h 14m |
| 80 mph (129 km/h) | 04h 34m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.71 | $47.94 | $95.89 |
| Mid-grade | $4.24 | $54.89 | $109.78 |
| Premium | $4.79 | $61.98 | $123.97 |
| Diesel | $4.30 | $55.69 | $111.39 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Ohio · Aug 03, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.