How far is Cherokee, AL from Mobile, AL?
The driving distance from Cherokee, AL to Mobile, AL is about 338.8 miles (545.2 km), with a travel time of about 05h 41m by car.
- The straight-line flight distance is about 280.7 miles (451.8 km).
- For a round trip, plan for roughly 11h 22m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CST.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 41m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Driving Route Map
The map below follows the saved road route between Cherokee and Mobile.
Turn-by-Turn Driving Directions
Step-by-step road directions between Cherokee and Mobile.
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1
Start on 2nd Street
10 m · 7 sec · 2nd Street
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2
Turn left onto Main Street
984 ft · 45 sec · Main Street
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3
Turn right
702 ft · 9 sec
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4
Continue straight
21.3 mi · 25 min
-
5
Take the exit slight right toward MS 365: Cairo, Miss., Savannah, Tenn.
633 ft · 27 sec
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6
Turn right
8.5 mi · 12 min
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7
Turn right
11.6 mi · 16 min
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8
At the end of the road, turn right
6.6 mi · 9 min
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9
Keep slight left to continue on US 45 South, MS 30 West: Tupelo, New Albany
6.4 mi · 8 min
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10
Continue straight
33.1 mi · 39 min
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11
Continue straight
1.4 mi · 2 min
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12
Continue straight
2.2 mi · 2 min
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13
Continue straight
1.5 mi · 2 min
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14
Continue straight
1.1 km · 49 sec
-
15
Continue straight
1.4 mi · 2 min
-
16
Continue on US Highway 45 Alternate
54.7 mi · 1 hr 6 min · US Highway 45 Alternate
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17
Continue on US Highway 45 Aiternate
60.6 mi · 1 hr 9 min · US Highway 45 Aiternate
-
18
Keep slight right
18.8 mi · 22 min
-
19
Continue straight
1.1 km · 46 sec
-
20
Continue straight
3.7 mi · 4 min
-
21
Continue straight
5.4 mi · 6 min
-
22
Continue straight
5.5 mi · 6 min
-
23
Continue straight
2.7 mi · 3 min
-
24
Continue straight
1.7 mi · 2 min
-
25
Continue straight
3.9 mi · 5 min
-
26
Continue straight
9.8 mi · 11 min
-
27
Continue straight
2 mi · 2 min
-
28
Continue straight
4.9 mi · 6 min
-
29
Continue straight
17.4 mi · 20 min
-
30
Keep slight left
51.6 mi · 59 min
-
31
Take the exit left
1680 ft · 46 sec
-
32
Merge slight left onto Industrial Parkway
2.3 mi · 4 min · Industrial Parkway
-
33
Take the exit slight right toward I 65 South: Mobile
2204 ft · 54 sec
-
34
Merge slight left
2.7 mi · 3 min
-
35
Take the exit slight right toward I 165: Mobile
3185 ft · 42 sec
-
36
Continue straight
4.7 mi · 6 min
-
37
Turn right onto Saint Joseph Street
1977 ft · 1 min · Saint Joseph Street
-
38
Turn right onto Saint Louis Street
12 m · 1 sec · Saint Louis Street
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39
Arrive at your destination
0 m · 1 sec · Saint Louis Street
Car Route Details
A richer read on the saved driving route between Cherokee and Mobile.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
US Highway 45 Aiternate
Continue on US Highway 45 Aiternate
60.6 mi · 01h 09m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Sunny leaving Cherokee and Mostly Sunny near Mobile.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Cherokee to Mobile?
The road trip is about 338.8 miles (545.2 km) and usually takes 05h 41m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Geiger is a useful midpoint, sitting about 175.1 miles from Cherokee and 163.7 miles from Mobile.
How much longer is the road route than the straight-line distance?
The direct path is about 280.7 miles (451.8 km), while the road route adds roughly 58.1 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CST. If you want a more comfortable same-day return, try to leave by 5:38 AM CST.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $43.83 one way or $87.67 round trip. Estimated CO2 is about 106.2 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Cherokee and Mostly Sunny near Mobile.
Stop Ideas Near Geiger
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Geiger.
Union Station
Tuscaloosa
Marion, AL
Brent, AL
Flight Path Map
This map shows the direct air route between Cherokee and Mobile. Straight-line distance: 280.74 mi (451.8 km).
#1 Cherokee
Town in Alabama, United States
| Population | 999 |
| Coordinates | 34.7570300, -87.9728100 |
| Altitude | 163 |
| Country | United States |
#2 Mobile
The second most populous city in Alabama.
| Population | 187,746 |
| Coordinates | 30.6943600, -88.0430500 |
| Altitude | 3 |
| Country | United States |
End: Saint Louis Street (-88.043038, 30.694332)
Estimated Travel Time
Distance: 545 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 11h 17m |
| 40 mph (64.37 km/h) | 08h 28m |
| 50 mph (80.47 km/h) | 06h 46m |
| 60 mph (96.56 km/h) | 05h 38m |
| 70 mph (112.65 km/h) | 04h 50m |
| 80 mph (129 km/h) | 04h 13m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.67 | $43.83 | $87.67 |
| Mid-grade | $4.15 | $49.64 | $99.28 |
| Premium | $4.55 | $54.42 | $108.84 |
| Diesel | $5.82 | $69.57 | $139.15 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Alabama · Nov 07, 2026