How far is Caruthersville, MO from Saint Charles, MO?
The driving distance from Caruthersville, MO to Saint Charles, MO is about 208.2 miles (335.1 km), with a travel time of about 03h 08m by car.
- The straight-line flight distance is about 184.6 miles (297.1 km).
- For a round trip, plan for roughly 06h 16m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 08m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Village in the United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny then Chance Showers And Thunderstorms
Mostly Sunny then Chance Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Caruthersville and Saint Charles.
Turn-by-Turn Driving Directions
Step-by-step road directions between Caruthersville and Saint Charles.
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1
Start on the route
14 m · 9 sec
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2
Turn left onto West 3rd Street
2.9 mi · 6 min · West 3rd Street
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3
Continue straight
2 mi · 4 min
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4
Take the ramp right toward I 55 North, US 61 North: Sikeston
1331 ft · 33 sec
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5
Merge slight left
74.2 mi · 1 hr 20 min
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6
Keep slight left
101.5 mi · 1 hr 49 min
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7
Continue on Rosa Parks Highway
1.3 mi · 2 min · Rosa Parks Highway
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8
Take the exit slight right toward I 270 West, I 255 East: Kansas City, Chicago
1279 ft · 27 sec
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9
Keep slight left to continue on I 270 West: Kansas City
118 m · 8 sec
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10
Continue on I 270 West
1.2 km · 1 min
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11
Merge slight left
18.1 mi · 23 min
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12
Take the exit slight right toward I 70: Kansas City, Saint Louis, Saint Louis Lambert International Airport
1 mi · 1 min
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13
Keep slight left to continue on I 70 West: Kansas City
645 ft · 11 sec
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14
Continue on I 70 West: Kansas City
1 km · 57 sec
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15
Merge slight left
2.7 mi · 3 min
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16
Take the exit slight right toward I 70 Business: Fifth Street
841 ft · 18 sec
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17
Keep slight right to continue on I 70 Business: Fifth Street North, Bass Pro Drive, Ameristar Boulevard
71 m · 5 sec
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18
Turn slight right onto South Fifth Street
1.6 km · 2 min · South Fifth Street
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19
Turn right onto Jefferson Street
1093 ft · 44 sec · Jefferson Street
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20
Turn left onto North Second Street
949 ft · 34 sec · North Second Street
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21
Arrive at your destination
0 m · 1 sec · North Second Street
Car Route Details
A richer read on the saved driving route between Caruthersville and Saint Charles.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 55 North
Keep slight left
102 mi · 01h 49m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Mostly Sunny then Chance Showers And Thunderstorms leaving Caruthersville and Mostly Sunny then Chance Showers And Thunderstorms near Saint Charles.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Caruthersville to Saint Charles?
The road trip is about 208.2 miles (335.1 km) and usually takes 03h 08m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Old Appleton is a useful midpoint, sitting about 103.9 miles from Caruthersville and 104.3 miles from Saint Charles.
How much longer is the road route than the straight-line distance?
The direct path is about 184.6 miles (297.1 km), while the road route adds roughly 23.6 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 10:44 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $27.72 one way or $55.43 round trip. Estimated CO2 is about 65.3 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny then Chance Showers And Thunderstorms around Caruthersville and Mostly Sunny then Chance Showers And Thunderstorms near Saint Charles.
Stop Ideas Near Old Appleton
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Old Appleton.
Carbondale station
Du Quoin
Marion, IL
Vienna, IL
Flight Path Map
This map shows the direct air route between Caruthersville and Saint Charles. Straight-line distance: 184.64 mi (297.15 km).
#1 Caruthersville
City in and county seat of Pemiscot County, Missouri, United States
| Population | 5,289 |
| Coordinates | 36.1931200, -89.6556400 |
| Altitude | 84 |
| Country | United States |
#2 Saint Charles
A city in St.
| Population | 71,761 |
| Coordinates | 38.7839400, -90.4812300 |
| Altitude | 147 |
| Country | United States |
End: North Second Street (-90.481269, 38.783952)
Estimated Travel Time
Distance: 335 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 06h 56m |
| 40 mph (64.37 km/h) | 05h 12m |
| 50 mph (80.47 km/h) | 04h 09m |
| 60 mph (96.56 km/h) | 03h 28m |
| 70 mph (112.65 km/h) | 02h 58m |
| 80 mph (129 km/h) | 02h 35m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $27.72 | $55.43 |
| Mid-grade | $4.25 | $31.26 | $62.52 |
| Premium | $4.65 | $34.21 | $68.41 |
| Diesel | $5.30 | $38.98 | $77.97 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Apr 17, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.