How far is Cape Coral, FL from Panama City Beach, FL?
The driving distance from Cape Coral, FL to Panama City Beach, FL is about 506.7 miles (815.4 km), with a travel time of about 09h 46m by car.
- The straight-line flight distance is about 342.4 miles (551.1 km).
- For a round trip, plan for roughly 19h 33m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 09h 46m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Florida, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Partly Sunny
Sunny
Driving Route Map
The map below follows the saved road route between Cape Coral and Panama City Beach.
Turn-by-Turn Driving Directions
Step-by-step road directions between Cape Coral and Panama City Beach.
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1
Start on the route
29 m · 7 sec
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2
Turn right onto Cape Coral Parkway East
38 m · 7 sec · Cape Coral Parkway East
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3
Turn right onto Vincennes Boulevard
109 m · 13 sec · Vincennes Boulevard
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4
Enter the roundabout and take exit 2 toward Vincennes Boulevard
19 m · 2 sec · Vincennes Boulevard
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5
Exit the roundabout onto Vincennes Boulevard
2436 ft · 1 min · Vincennes Boulevard
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6
Turn right onto Coronado Parkway
1 km · 2 min · Coronado Parkway
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7
Turn left onto Del Prado Boulevard South
5.2 mi · 11 min · Del Prado Boulevard South
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8
Continue on Del Prado Boulevard North
6.5 mi · 11 min · Del Prado Boulevard North
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9
Turn left onto North Tamiami Trail
10.4 mi · 13 min · North Tamiami Trail
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10
Turn right onto Tuckers Grade
1.1 mi · 2 min · Tuckers Grade
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11
Take the ramp slight left toward I 75 North: Tampa
2299 ft · 56 sec
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12
Merge slight left
276.8 mi · 4 hr 58 min
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13
Take the exit slight right toward I 10: Jacksonville, Tallahassee
820 ft · 16 sec
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14
Keep slight left to continue on I 10 West: Tallahassee
1569 ft · 30 sec
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15
Merge slight right
121.8 mi · 2 hr 11 min
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16
Take the exit slight right toward FL 12: Gretna, Greensboro
1341 ft · 46 sec
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17
Keep slight left to continue on FL `12 South: Greensboro
112 m · 11 sec
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18
Turn straight onto Greensboro Highway
2.4 mi · 4 min · Greensboro Highway
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19
Continue on Selman Street
3018 ft · 1 min · Selman Street
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20
Turn left onto Green Avenue
2342 ft · 57 sec · Green Avenue
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21
Continue on Bristol Highway
17.7 mi · 23 min · Bristol Highway
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22
At the end of the road, turn right
28.4 mi · 39 min
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23
Turn left
22.5 mi · 30 min
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24
Turn right onto East 23rd Street
5.4 mi · 9 min · East 23rd Street
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25
Take the ramp slight left
1693 ft · 43 sec
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26
Merge slight left
2 mi · 3 min
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27
Continue on Front Beach Road
2.6 mi · 5 min · Front Beach Road
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28
Turn left onto South Thomas Drive
146 m · 15 sec · South Thomas Drive
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29
Turn right
18 m · 4 sec
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30
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between Cape Coral and Panama City Beach.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
I 75 North
Merge slight left
277 mi · 04h 58m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Partly Sunny leaving Cape Coral and Sunny near Panama City Beach.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Cape Coral to Panama City Beach?
The road trip is about 506.7 miles (815.4 km) and usually takes 09h 46m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
West Park is a useful midpoint, sitting about 253.5 miles from Cape Coral and 253.1 miles from Panama City Beach.
How much longer is the road route than the straight-line distance?
The direct path is about 342.4 miles (551.1 km), while the road route adds roughly 164.3 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM EDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $74.17 one way or $148.33 round trip. Estimated CO2 is about 158.9 kg one way.
Do you cross a time zone on this route?
Yes. There is about a 1 hour time difference between Cape Coral and Panama City Beach, so arrival and return times should be read in local time.
What should you check before leaving?
Before you leave, expect Partly Sunny around Cape Coral and Sunny near Panama City Beach.
Stop Ideas Near West Park
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to West Park.
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Palatka
Flight Path Map
This map shows the direct air route between Cape Coral and Panama City Beach. Straight-line distance: 342.43 mi (551.09 km).
#1 Cape Coral
The second most populous city in Lee County, Florida.
| Population | 200,972 |
| Coordinates | 26.5628500, -81.9495300 |
| Altitude | 1 |
| Country | United States |
#2 Panama City Beach
City in the U.
| Population | 12,337 |
| Coordinates | 30.1765900, -85.8054900 |
| Altitude | 3 |
| Country | United States |
End: Panama City Beach (-85.80549, 30.17659)
Estimated Travel Time
Distance: 815 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 16h 52m |
| 40 mph (64.37 km/h) | 12h 39m |
| 50 mph (80.47 km/h) | 10h 07m |
| 60 mph (96.56 km/h) | 08h 26m |
| 70 mph (112.65 km/h) | 07h 14m |
| 80 mph (129 km/h) | 06h 19m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.15 | $74.17 | $148.33 |
| Mid-grade | $4.60 | $82.18 | $164.35 |
| Premium | $4.90 | $87.54 | $175.08 |
| Diesel | $4.35 | $77.78 | $155.56 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Florida · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.