How far is Cape Coral, FL from Key West, FL?
The driving distance from Cape Coral, FL to Key West, FL is about 297.2 miles (478.3 km), with a travel time of about 06h 36m by car.
- The straight-line flight distance is about 139.1 miles (223.9 km).
- For a round trip, plan for roughly 13h 13m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 06h 36m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
This departure sits inside the recommended comfort window for the route.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Census-designated place in Miami-Dade County, Florida
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny then Scattered Showers And Thunderstorms
Slight Chance Showers And Thunderstorms then Chance Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Cape Coral and Key West.
Turn-by-Turn Driving Directions
Step-by-step road directions between Cape Coral and Key West.
-
1
Start on the route
29 m · 7 sec
-
2
Turn right onto Cape Coral Parkway East
38 m · 9 sec · Cape Coral Parkway East
-
3
Continue on Cape Coral Parkway East
1.1 mi · 2 min · Cape Coral Parkway East
-
4
Continue on Cape Coral Bridge Road
1.5 km · 2 min · Cape Coral Bridge Road
-
5
Continue on College Parkway
2.9 mi · 5 min · College Parkway
-
6
Turn right onto South Cleveland Avenue
1.1 km · 1 min · South Cleveland Avenue
-
7
Turn left onto Daniels Parkway
4.6 mi · 8 min · Daniels Parkway
-
8
Take the ramp slight right toward I 75 South: Naples
2673 ft · 1 min
-
9
Merge slight left
106.5 mi · 1 hr 54 min
-
10
Take the exit slight right toward US 27: Miami, South Bay
1118 ft · 21 sec
-
11
Keep slight right to continue on US 27 South: Miami
2407 ft · 59 sec
-
12
Merge slight left
9.2 mi · 11 min
-
13
Keep slight right
8.6 mi · 11 min
-
14
Take the exit right toward Florida's Turnpike South: Homestead, Key West
1324 ft · 32 sec
-
15
Merge slight left onto Homestead Extension of Florida's Turnpike
34.5 mi · 41 min · Homestead Extension of Florida's Turnpike
-
16
Keep slight left
2930 ft · 1 min
-
17
Merge slight left onto Dixie Highway
19.2 mi · 27 min · Dixie Highway
-
18
Continue on Overseas Highway
104.2 mi · 2 hr 43 min · Overseas Highway
-
19
Turn right onto North Roosevelt Boulevard
2.4 mi · 6 min · North Roosevelt Boulevard
-
20
Turn left onto George Street
1845 ft · 1 min · George Street
-
21
Arrive at your destination
0 m · 1 sec · George Street
Car Route Details
A richer read on the saved driving route between Cape Coral and Key West.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 75 South
Merge slight left
107 mi · 01h 54m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Mostly Sunny then Scattered Showers And Thunderstorms leaving Cape Coral and Slight Chance Showers And Thunderstorms then Chance Showers And Thunderstorms near Key West.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Cape Coral to Key West?
The road trip is about 297.2 miles (478.3 km) and usually takes 06h 36m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Westwood Lake is a useful midpoint, sitting about 148.7 miles from Cape Coral and 148.6 miles from Key West.
How much longer is the road route than the straight-line distance?
The direct path is about 139.1 miles (223.9 km), while the road route adds roughly 158.1 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM EDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $43.51 one way or $87.03 round trip. Estimated CO2 is about 93.2 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny then Scattered Showers And Thunderstorms around Cape Coral and Slight Chance Showers And Thunderstorms then Chance Showers And Thunderstorms near Key West.
Stop Ideas Near Westwood Lake
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Basketball Court
Hialeah City Hall
Hialeah Gardens Community Hall
Historic Homestead Town Hall Museum
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Westwood Lake.
Miami Intermodal Center
Hollywood
Fort Lauderdale
Deerfield Beach
Flight Path Map
This map shows the direct air route between Cape Coral and Key West. Straight-line distance: 139.11 mi (223.87 km).
#1 Cape Coral
The second most populous city in Lee County, Florida.
| Population | 200,972 |
| Coordinates | 26.5628500, -81.9495300 |
| Altitude | 1 |
| Country | United States |
#2 Key West
County seat city of Monroe County, Florida, United States; island in Florida Keys
| Population | 23,767 |
| Coordinates | 24.5552400, -81.7816300 |
| Altitude | 1 |
| Country | United States |
End: Key West (-81.78163, 24.55524)
Estimated Travel Time
Distance: 478 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 09h 54m |
| 40 mph (64.37 km/h) | 07h 25m |
| 50 mph (80.47 km/h) | 05h 56m |
| 60 mph (96.56 km/h) | 04h 57m |
| 70 mph (112.65 km/h) | 04h 14m |
| 80 mph (129 km/h) | 03h 42m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.15 | $43.51 | $87.03 |
| Mid-grade | $4.60 | $48.21 | $96.42 |
| Premium | $4.90 | $51.36 | $102.72 |
| Diesel | $4.35 | $45.63 | $91.26 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Florida · May 26, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.