How far is Biloxi, MS from Greenwood, MS?
The driving distance from Biloxi, MS to Greenwood, MS is about 309.3 miles (497.8 km), with a travel time of about 06h 25m by car.
- The straight-line flight distance is about 265 miles (426.4 km).
- For a round trip, plan for roughly 12h 51m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 06h 25m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Town in Clarke County, Mississippi, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Slight Chance Rain Showers then Mostly Cloudy
Chance Rain Showers then Partly Sunny
Driving Route Map
The map below follows the saved road route between Biloxi and Greenwood.
Turn-by-Turn Driving Directions
Step-by-step road directions between Biloxi and Greenwood.
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1
Start on Howard Avenue
28 m · 6 sec · Howard Avenue
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2
Turn right onto Main Street
2572 ft · 1 min · Main Street
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3
Turn left onto Division Street
2603 ft · 2 min · Division Street
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4
Take the ramp right toward Bohn Street
42 m · 3 sec · Bohn Street
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5
Turn straight
1522 ft · 37 sec
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6
Merge slight left
3.1 mi · 4 min
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7
Continue straight
20.7 mi · 24 min
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8
Keep slight right to continue on US 49 North: Hattiesburg, Jackson
2209 ft · 47 sec
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9
Merge slight left
39.8 mi · 47 min
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10
Continue straight
2.4 mi · 3 min
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11
Take the exit straight
1520 ft · 52 sec
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12
Merge slight left
2.5 mi · 3 min
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13
Take the exit slight right toward I 59 North, US 98 West: Columbia, Laurel
1.3 km · 2 min
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14
Merge slight left onto Lance Corporal Roy M Wheat Memorial Highway
88.4 mi · 1 hr 35 min · Lance Corporal Roy M Wheat Memorial Highway
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15
Keep slight right to continue on I 59 North, I 20 East: Meridian, Tuscaloosa
9 mi · 11 min
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16
Take the exit slight right toward US 45 North: Macon
1383 ft · 47 sec
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17
Merge slight left
65.1 mi · 1 hr 14 min
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18
Keep slight right to continue on US 45 North: Columbus, Aberdeen
3.4 mi · 4 min
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19
Continue straight
14.3 mi · 17 min
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20
Continue on Plymouth Bluff Access Road
95 m · 6 sec · Plymouth Bluff Access Road
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21
Take the exit right toward US 82 East, US 45 North, MS 12 East: Columbus
3.9 mi · 5 min
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22
Take the exit slight right toward US 45 North: Aberdeen
2885 ft · 56 sec
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23
Continue straight
13 mi · 17 min
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24
Continue straight
2 mi · 2 min
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25
Continue straight
1.9 mi · 2 min
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26
Continue straight
1.8 mi · 2 min
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27
Continue straight
1.3 km · 55 sec
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28
Continue straight
2.2 mi · 3 min
-
29
Continue straight
1.2 km · 52 sec
-
30
Continue straight
1370 ft · 18 sec
-
31
Take the exit slight right toward MS 25 North, MS 8 East: Amory
1831 ft · 50 sec
-
32
Continue straight
6.5 mi · 10 min
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33
Turn left onto Highway 125
5.2 mi · 9 min · Highway 125
-
34
Turn right
2013 ft · 60 sec
-
35
Turn left onto South Main Street
1.1 mi · 2 min · South Main Street
-
36
Turn left onto State Highway 6
2.5 mi · 4 min · State Highway 6
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37
Turn right onto State Highway 371
10.1 mi · 18 min · State Highway 371
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38
Turn right onto Dorsey Evergreen Road
4.3 mi · 17 min · Dorsey Evergreen Road
-
39
Turn sharp left onto Greenwood Hopewell Road
44 m · 6 sec · Greenwood Hopewell Road
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40
Arrive at your destination
0 m · 1 sec · Greenwood Hopewell Road
Car Route Details
A richer read on the saved driving route between Biloxi and Greenwood.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Lance Corporal Roy M Wheat Memorial Highway
Merge slight left onto Lance Corporal Roy M Wheat Memorial Highway
88.4 mi · 01h 35m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Slight Chance Rain Showers then Mostly Cloudy leaving Biloxi and Chance Rain Showers then Partly Sunny near Greenwood.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Biloxi to Greenwood?
The road trip is about 309.3 miles (497.8 km) and usually takes 06h 25m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Enterprise is a useful midpoint, sitting about 154.9 miles from Biloxi and 154.4 miles from Greenwood.
How much longer is the road route than the straight-line distance?
The direct path is about 265 miles (426.4 km), while the road route adds roughly 44.3 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM CDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $41.35 one way or $82.71 round trip. Estimated CO2 is about 97 kg one way.
What should you check before leaving?
Before you leave, expect Slight Chance Rain Showers then Mostly Cloudy around Biloxi and Chance Rain Showers then Partly Sunny near Greenwood.
Stop Ideas Near Enterprise
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Enterprise.
Union Station
Laurel station
Hattiesburg, MS
Hattiesburg station
Flight Path Map
This map shows the direct air route between Biloxi and Greenwood. Straight-line distance: 264.97 mi (426.43 km).
#1 Biloxi
The most populous city in Harrison County, Mississippi.
| Population | 46,127 |
| Coordinates | 30.3960300, -88.8853100 |
| Altitude | 6 |
| Country | United States |
#2 Greenwood
County seat of Leflore County, Mississippi, United States
| Population | 13,457 |
| Coordinates | 34.2178800, -88.5100500 |
| Altitude | 97 |
| Country | United States |
End: Greenwood (-88.51005, 34.21788)
Estimated Travel Time
Distance: 498 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 10h 18m |
| 40 mph (64.37 km/h) | 07h 44m |
| 50 mph (80.47 km/h) | 06h 11m |
| 60 mph (96.56 km/h) | 05h 09m |
| 70 mph (112.65 km/h) | 04h 25m |
| 80 mph (129 km/h) | 03h 51m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.79 | $41.35 | $82.71 |
| Mid-grade | $4.26 | $46.51 | $93.02 |
| Premium | $4.63 | $50.51 | $101.01 |
| Diesel | $5.42 | $59.13 | $118.26 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Mississippi · Apr 19, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.