How far is Biloxi, MS from City of Greenville, MS?
The driving distance from Biloxi, MS to City of Greenville, MS is about 284.2 miles (457.4 km), with a travel time of about 04h 49m by car.
- The straight-line flight distance is about 242.5 miles (390.2 km).
- For a round trip, plan for roughly 09h 38m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 49m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Human settlement in Simpson County, Mississippi, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Slight Chance Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Biloxi and City of Greenville.
Turn-by-Turn Driving Directions
Step-by-step road directions between Biloxi and City of Greenville.
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1
Start on Howard Avenue
28 m · 4 sec · Howard Avenue
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2
Turn right onto Main Street
2572 ft · 1 min · Main Street
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3
Turn left onto Division Street
2603 ft · 2 min · Division Street
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4
Take the ramp right toward Bohn Street
42 m · 3 sec · Bohn Street
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5
Turn straight
1522 ft · 37 sec
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6
Merge slight left
3.1 mi · 4 min
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7
Continue straight
20.7 mi · 24 min
-
8
Keep slight right to continue on US 49 North: Hattiesburg, Jackson
2209 ft · 47 sec
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9
Merge slight left
39.8 mi · 47 min
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10
Continue straight
2.4 mi · 3 min
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11
Turn straight
10.3 mi · 16 min
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12
Continue straight
5.4 mi · 7 min
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13
Continue straight
5.5 mi · 6 min
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14
Continue straight
69.9 mi · 1 hr 25 min
-
15
Take the exit slight right
862 ft · 21 sec
-
16
Keep slight left to continue on Jackson
1.1 km · 1 min
-
17
Keep slight left
1 mi · 1 min
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18
Merge slight right
1.6 mi · 2 min
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19
Keep slight right to continue on I 20 West, US 49 North: Vicksburg, Yazoo City
2.7 mi · 3 min
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20
Take the exit slight right toward I 220 North, I 49 North: North Jackson, Yazoo City
5.2 mi · 6 min
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21
Take the exit slight right toward US 49 North: Yazoo City
1360 ft · 33 sec
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22
Merge slight left onto Medgar Evers Boulevard
39.5 mi · 49 min · Medgar Evers Boulevard
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23
Take the exit slight right toward US 49W North, MS 3 South: Indianola, Vicksburg
46.7 mi · 57 min
-
24
Turn left
2.4 mi · 3 min
-
25
Keep slight left
1876 ft · 29 sec
-
26
Keep slight left
13.1 mi · 16 min
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27
Turn right
8.3 mi · 12 min
-
28
Turn left onto Martin Luther King Junior Boulevard
1 mi · 2 min · Martin Luther King Junior Boulevard
-
29
Turn right onto East Reed Road
1.2 km · 1 min · East Reed Road
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30
Turn left onto Sandy Avenue
14 m · 2 sec · Sandy Avenue
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31
Arrive at your destination
0 m · 1 sec · Sandy Avenue
Car Route Details
A richer read on the saved driving route between Biloxi and City of Greenville.
Interchange-aware route
The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.
US 49 North
Continue straight
69.9 mi · 01h 25m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Sunny leaving Biloxi and Slight Chance Showers And Thunderstorms near City of Greenville.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Biloxi to City of Greenville?
The road trip is about 284.2 miles (457.4 km) and usually takes 04h 49m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Braxton is a useful midpoint, sitting about 141.4 miles from Biloxi and 142.8 miles from City of Greenville.
How much longer is the road route than the straight-line distance?
The direct path is about 242.5 miles (390.2 km), while the road route adds roughly 41.7 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 7:22 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $37.98 one way or $75.97 round trip. Estimated CO2 is about 89.1 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Biloxi and Slight Chance Showers And Thunderstorms near City of Greenville.
Stop Ideas Near Braxton
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Braxton.
Union Station
Hazlehurst station
Brookhaven
Laurel station
Flight Path Map
This map shows the direct air route between Biloxi and City of Greenville. Straight-line distance: 242.47 mi (390.21 km).
#1 Biloxi
The most populous city in Harrison County, Mississippi.
| Population | 46,127 |
| Coordinates | 30.3960300, -88.8853100 |
| Altitude | 6 |
| Country | United States |
#2 City of Greenville
City in Washington County, Mississippi, United States
| Population | 30,686 |
| Coordinates | 33.3850200, -91.0514200 |
| Altitude | 40 |
| Country | United States |
End: Sandy Avenue (-91.051544, 33.385041)
Estimated Travel Time
Distance: 457 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 09h 28m |
| 40 mph (64.37 km/h) | 07h 06m |
| 50 mph (80.47 km/h) | 05h 41m |
| 60 mph (96.56 km/h) | 04h 44m |
| 70 mph (112.65 km/h) | 04h 03m |
| 80 mph (129 km/h) | 03h 32m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.79 | $37.98 | $75.97 |
| Mid-grade | $4.26 | $42.72 | $85.44 |
| Premium | $4.63 | $46.39 | $92.78 |
| Diesel | $5.42 | $54.31 | $108.62 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Mississippi · Jun 12, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.