How far is Wentzville, MO from Chillicothe, MO?
The driving distance from Wentzville, MO to Chillicothe, MO is about 195.6 miles (314.8 km), with a travel time of about 03h 54m by car.
- The straight-line flight distance is about 159.5 miles (256.7 km).
- For a round trip, plan for roughly 07h 48m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 54m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Monroe County, Missouri, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Showers And Thunderstorms
Chance Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Wentzville and Chillicothe.
Turn-by-Turn Driving Directions
Step-by-step road directions between Wentzville and Chillicothe.
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1
Start on East Allen Street
12 m · 4 sec · East Allen Street
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2
Turn right onto North Linn Avenue
65 m · 11 sec · North Linn Avenue
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3
Turn right onto East Pearce Boulevard
2689 ft · 1 min · East Pearce Boulevard
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4
Turn left onto Luetkenhaus Boulevard
2862 ft · 1 min · Luetkenhaus Boulevard
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5
Enter the roundabout and take exit 1 toward Luetkenhaus Boulevard
36 m · 3 sec · Luetkenhaus Boulevard
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6
Exit the roundabout onto Luetkenhaus Boulevard
586 ft · 19 sec · Luetkenhaus Boulevard
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7
At the end of the road, turn right onto Wentzville Parkway
925 ft · 25 sec · Wentzville Parkway
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8
Take the ramp left toward US 61 North
1192 ft · 17 sec
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9
Merge slight left onto Avenue of the Saints
71.9 mi · 1 hr 25 min · Avenue of the Saints
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10
Take the exit slight left
76 m · 15 sec
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11
Turn left onto Paris Gravel Road
2645 ft · 1 min · Paris Gravel Road
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12
Keep slight right to continue on County Road 422
85 m · 9 sec · County Road 422
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13
Turn right onto Veterans Road
2.2 mi · 4 min · Veterans Road
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14
Take the ramp left toward US 36 West, MO 110 West: Monroe City
1226 ft · 16 sec
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15
Merge slight left onto V.F.W. Memorial Highway
5.8 mi · 7 min · V.F.W. Memorial Highway
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16
Continue on Chicago-Kansas City Expressway
111.4 mi · 2 hr 9 min · Chicago-Kansas City Expressway
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17
Take the exit slight right toward US 65, US 36 Business: Chillicothe, Carrollton
975 ft · 28 sec
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18
Turn right onto South Washington Street
1.4 mi · 3 min · South Washington Street
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19
Turn right onto Jackson Street
98 m · 15 sec · Jackson Street
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20
Turn left onto Locust Street
687 ft · 30 sec · Locust Street
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21
Arrive at your destination
0 m · 1 sec · Locust Street
Car Route Details
A richer read on the saved driving route between Wentzville and Chillicothe.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Chicago-Kansas City Expressway
Continue on Chicago-Kansas City Expressway
111 mi · 02h 09m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Showers And Thunderstorms leaving Wentzville and Chance Showers And Thunderstorms near Chillicothe.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Wentzville to Chillicothe?
The road trip is about 195.6 miles (314.8 km) and usually takes 03h 54m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Monroe City is a useful midpoint, sitting about 97.7 miles from Wentzville and 97.9 miles from Chillicothe.
How much longer is the road route than the straight-line distance?
The direct path is about 159.5 miles (256.7 km), while the road route adds roughly 36.1 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 9:12 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $27.43 one way or $54.86 round trip. Estimated CO2 is about 61.3 kg one way.
What should you check before leaving?
Before you leave, expect Showers And Thunderstorms around Wentzville and Chance Showers And Thunderstorms near Chillicothe.
Stop Ideas Near Monroe City
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Monroe City.
Quincy
La Plata
Hermann
Fort Madison station
Flight Path Map
This map shows the direct air route between Wentzville and Chillicothe. Straight-line distance: 159.52 mi (256.73 km).
#1 Wentzville
A city in St.
| Population | 43,109 |
| Coordinates | 38.8114400, -90.8529100 |
| Altitude | 190 |
| Country | United States |
#2 Chillicothe
City in Missouri
| Population | 8,915 |
| Coordinates | 39.7952900, -93.5524400 |
| Altitude | 243 |
| Country | United States |
End: Chillicothe (-93.55244, 39.79529)
Estimated Travel Time
Distance: 315 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 06h 31m |
| 40 mph (64.37 km/h) | 04h 53m |
| 50 mph (80.47 km/h) | 03h 54m |
| 60 mph (96.56 km/h) | 03h 15m |
| 70 mph (112.65 km/h) | 02h 47m |
| 80 mph (129 km/h) | 02h 26m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.98 | $27.43 | $54.86 |
| Mid-grade | $4.34 | $29.95 | $59.91 |
| Premium | $4.71 | $32.48 | $64.96 |
| Diesel | $5.99 | $41.32 | $82.63 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Oct 15, 2026