How far is Tupelo, MS from Yazoo City, MS?
The driving distance from Tupelo, MS to Yazoo City, MS is about 171.5 miles (276 km), with a travel time of about 03h 55m by car.
- The straight-line flight distance is about 137.8 miles (221.8 km).
- For a round trip, plan for roughly 07h 51m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 55m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Town of the United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Showers And Thunderstorms Likely
Showers And Thunderstorms Likely
Driving Route Map
The map below follows the saved road route between Tupelo and Yazoo City.
Turn-by-Turn Driving Directions
Step-by-step road directions between Tupelo and Yazoo City.
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1
Start on North Spring Street
21 m · 8 sec · North Spring Street
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2
Turn left onto Court Street
85 m · 18 sec · Court Street
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3
Turn left onto North Broadway Street
91 m · 17 sec · North Broadway Street
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4
Turn right onto West Main Street
2.9 mi · 7 min · West Main Street
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5
Turn left
1533 ft · 1 min
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6
At the end of the road, turn left onto Natchez Trace Parkway
45.4 mi · 1 hr 8 min · Natchez Trace Parkway
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7
Turn right onto County Road 285
691 ft · 31 sec · County Road 285
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8
At the end of the road, turn left
9.5 mi · 14 min
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9
Take the ramp slight right
2 mi · 4 min
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10
Continue straight
40.2 mi · 47 min
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11
Take the exit slight left
1837 ft · 47 sec
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12
Merge slight left
45.3 mi · 49 min
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13
Take the exit slight right
1669 ft · 41 sec
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14
Turn straight
13.5 mi · 24 min
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15
At the end of the road, turn left onto Mississippi 433
1.2 mi · 2 min · Mississippi 433
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16
Continue on Old Highway 16
950 ft · 19 sec · Old Highway 16
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17
Continue on Old Hwy 16
1.3 mi · 3 min · Old Hwy 16
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18
Turn right
6.1 mi · 8 min
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19
Turn right
1971 ft · 41 sec
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20
Turn left onto East Broadway Street
1.6 mi · 3 min · East Broadway Street
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21
Turn right onto North Washington Street
1677 ft · 46 sec · North Washington Street
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22
Turn right onto East Canal Street
1216 ft · 40 sec · East Canal Street
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23
Turn left onto Grand Avenue
1484 ft · 46 sec · Grand Avenue
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24
Turn left onto East 5th Street
20 m · 3 sec · East 5th Street
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25
Arrive at your destination
0 m · 1 sec · East 5th Street
Car Route Details
A richer read on the saved driving route between Tupelo and Yazoo City.
Straightforward drive
The saved road route has a manageable number of maneuvers and should be easy to follow with normal attention to signs.
Natchez Trace Parkway
At the end of the road, turn left onto Natchez Trace Parkway
45.4 mi · 01h 08m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Showers And Thunderstorms Likely leaving Tupelo and Showers And Thunderstorms Likely near Yazoo City.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Tupelo to Yazoo City?
The road trip is about 171.5 miles (276 km) and usually takes 03h 55m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Kilmichael is a useful midpoint, sitting about 85.7 miles from Tupelo and 85.7 miles from Yazoo City.
How much longer is the road route than the straight-line distance?
The direct path is about 137.8 miles (221.8 km), while the road route adds roughly 33.7 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 9:08 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $22.91 one way or $45.82 round trip. Estimated CO2 is about 53.8 kg one way.
What should you check before leaving?
Before you leave, expect Showers And Thunderstorms Likely around Tupelo and Showers And Thunderstorms Likely near Yazoo City.
Stop Ideas Near Kilmichael
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Kilmichael.
Greenwood
Yazoo City
Flight Path Map
This map shows the direct air route between Tupelo and Yazoo City. Straight-line distance: 137.8 mi (221.76 km).
#1 Tupelo
City in and county seat of Lee County, Mississippi, United States
| Population | 38,303 |
| Coordinates | 34.2580700, -88.7046400 |
| Altitude | 85 |
| Country | United States |
#2 Yazoo City
City in Mississippi, United States
| Population | 10,869 |
| Coordinates | 32.8551300, -90.4056500 |
| Altitude | 34 |
| Country | United States |
End: Yazoo City (-90.40565, 32.85513)
Estimated Travel Time
Distance: 276 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 05h 42m |
| 40 mph (64.37 km/h) | 04h 17m |
| 50 mph (80.47 km/h) | 03h 25m |
| 60 mph (96.56 km/h) | 02h 51m |
| 70 mph (112.65 km/h) | 02h 26m |
| 80 mph (129 km/h) | 02h 08m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.79 | $22.91 | $45.82 |
| Mid-grade | $4.26 | $25.77 | $51.53 |
| Premium | $4.63 | $27.98 | $55.96 |
| Diesel | $5.42 | $32.76 | $65.52 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Mississippi · May 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.