How far is Tupelo, MS from Tylertown, MS?
The driving distance from Tupelo, MS to Tylertown, MS is about 280.3 miles (451.1 km), with a travel time of about 05h 28m by car.
- The straight-line flight distance is about 232.6 miles (374.4 km).
- For a round trip, plan for roughly 10h 57m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 28m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in and the county seat of Lauderdale County, Mississippi, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Partly Sunny then Slight Chance Showers And Thunderstorms
Partly Sunny
Driving Route Map
The map below follows the saved road route between Tupelo and Tylertown.
Turn-by-Turn Driving Directions
Step-by-step road directions between Tupelo and Tylertown.
-
1
Start on North Spring Street
21 m · 5 sec · North Spring Street
-
2
Turn right onto Court Street
97 m · 16 sec · Court Street
-
3
Turn right onto North Front Street
87 m · 15 sec · North Front Street
-
4
Turn left onto East Main Street
2407 ft · 1 min · East Main Street
-
5
Take the ramp straight
2248 ft · 56 sec
-
6
Merge slight left onto Martin Luther King Drive
1.6 km · 1 min · Martin Luther King Drive
-
7
Continue on Martin Luther King, Junior Drive
2.3 mi · 3 min · Martin Luther King, Junior Drive
-
8
Continue on Martin Luther King Drive
7.7 mi · 9 min · Martin Luther King Drive
-
9
Continue straight
1.4 mi · 2 min
-
10
Continue straight
2.2 mi · 2 min
-
11
Continue straight
1.5 mi · 2 min
-
12
Continue straight
1.1 km · 49 sec
-
13
Continue straight
1.4 mi · 2 min
-
14
Continue on US Highway 45 Alternate
54.7 mi · 1 hr 6 min · US Highway 45 Alternate
-
15
Continue on US Highway 45 Aiternate
60.6 mi · 1 hr 9 min · US Highway 45 Aiternate
-
16
Keep slight right
3.9 mi · 4 min
-
17
Take the exit slight right toward I 59 South, I 20 West: Meridian
2689 ft · 1 min
-
18
Merge slight left
6.3 mi · 8 min
-
19
Continue straight
1.8 mi · 2 min
-
20
Keep slight left to continue on I 59 South: Laurel, New Orleans
82.8 mi · 1 hr 30 min
-
21
Take the exit slight right toward US 98 West: Columbia, Hardy Street
862 ft · 21 sec
-
22
Keep slight left to continue on US 98 West: Hardy Street, University of Southern Mississippi, Columbia
72 m · 8 sec
-
23
Turn right onto Hardy Street
1.6 mi · 3 min · Hardy Street
-
24
Continue straight
1971 ft · 38 sec
-
25
Continue straight
1353 ft · 23 sec
-
26
Continue straight
3.1 mi · 4 min
-
27
Continue straight
1.7 mi · 2 min
-
28
Continue straight
40.3 mi · 49 min
-
29
Turn left
2.9 mi · 4 min
-
30
Arrive at your destination
0 m · 1 sec · Beulah Avenue
Car Route Details
A richer read on the saved driving route between Tupelo and Tylertown.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 59 South
Keep slight left to continue on I 59 South: Laurel, New Orleans
82.8 mi · 01h 30m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Partly Sunny then Slight Chance Showers And Thunderstorms leaving Tupelo and Partly Sunny near Tylertown.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Tupelo to Tylertown?
The road trip is about 280.3 miles (451.1 km) and usually takes 05h 28m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Meridian is a useful midpoint, sitting about 140.3 miles from Tupelo and 140 miles from Tylertown.
How much longer is the road route than the straight-line distance?
The direct path is about 232.6 miles (374.4 km), while the road route adds roughly 47.7 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 6:02 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $37.45 one way or $74.91 round trip. Estimated CO2 is about 87.9 kg one way.
What should you check before leaving?
Before you leave, expect Partly Sunny then Slight Chance Showers And Thunderstorms around Tupelo and Partly Sunny near Tylertown.
Stop Ideas Near Meridian
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Meridian.
Union Station
Laurel station
Thomasville, AL
Grove Hill, AL
Flight Path Map
This map shows the direct air route between Tupelo and Tylertown. Straight-line distance: 232.62 mi (374.37 km).
#1 Tupelo
City in and county seat of Lee County, Mississippi, United States
| Population | 38,303 |
| Coordinates | 34.2580700, -88.7046400 |
| Altitude | 85 |
| Country | United States |
#2 Tylertown
City in Walthall County, Mississippi, United States of America
| Population | 1,419 |
| Coordinates | 31.1160100, -90.1420300 |
| Altitude | 89 |
| Country | United States |
End: Tylertown (-90.14203, 31.11601)
Estimated Travel Time
Distance: 451 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 09h 20m |
| 40 mph (64.37 km/h) | 07h 00m |
| 50 mph (80.47 km/h) | 05h 36m |
| 60 mph (96.56 km/h) | 04h 40m |
| 70 mph (112.65 km/h) | 04h 00m |
| 80 mph (129 km/h) | 03h 29m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.79 | $37.45 | $74.91 |
| Mid-grade | $4.26 | $42.12 | $84.24 |
| Premium | $4.63 | $45.74 | $91.48 |
| Diesel | $5.42 | $53.55 | $107.11 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Mississippi · Apr 18, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.