How far is Tupelo, MS from Louisville, MS?
The driving distance from Tupelo, MS to Louisville, MS is about 101.9 miles (164 km), with a travel time of about 02h 04m by car.
- The straight-line flight distance is about 80.9 miles (130.2 km).
- For a round trip, plan for roughly 04h 08m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM CDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 02h 04m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Federal service academy in West Point, New York, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Showers And Thunderstorms
Chance Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Tupelo and Louisville.
Turn-by-Turn Driving Directions
Step-by-step road directions between Tupelo and Louisville.
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1
Start on North Spring Street
21 m · 5 sec · North Spring Street
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2
Turn right onto Court Street
97 m · 16 sec · Court Street
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3
Turn right onto North Front Street
87 m · 15 sec · North Front Street
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4
Turn left onto East Main Street
2407 ft · 1 min · East Main Street
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5
Take the ramp straight
2248 ft · 56 sec
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6
Merge slight left onto Martin Luther King Drive
1.6 km · 1 min · Martin Luther King Drive
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7
Continue on Martin Luther King, Junior Drive
2.3 mi · 3 min · Martin Luther King, Junior Drive
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8
Continue on Martin Luther King Drive
7.7 mi · 9 min · Martin Luther King Drive
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9
Continue straight
1.4 mi · 2 min
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10
Continue straight
2.2 mi · 2 min
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11
Continue straight
1.5 mi · 2 min
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12
Continue straight
1.1 km · 49 sec
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13
Continue straight
1.4 mi · 2 min
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14
Continue on US Highway 45 Alternate
35.7 mi · 44 min · US Highway 45 Alternate
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15
Take the exit slight right toward US 82 West, MS 12 West, MS 25 South: Starkville
11.8 mi · 13 min
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16
Take the exit slight right toward MS 25 South: Louisville
5 mi · 7 min
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17
Continue straight
1.9 mi · 2 min
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18
Keep slight right
24.9 mi · 28 min
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19
Continue on Stockyard Road
1456 ft · 23 sec · Stockyard Road
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20
At the end of the road, turn left onto North Church Avenue
3.1 mi · 6 min · North Church Avenue
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21
Turn left onto MS-14/West Main Street
30 m · 2 sec · MS-14/West Main Street
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22
Arrive at your destination
0 m · 1 sec · MS-14/West Main Street
Car Route Details
A richer read on the saved driving route between Tupelo and Louisville.
Straightforward drive
The saved road route has a manageable number of maneuvers and should be easy to follow with normal attention to signs.
US Highway 45 Alternate
Continue on US Highway 45 Alternate
35.7 mi · 00h 44m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Chance Showers And Thunderstorms leaving Tupelo and Chance Showers And Thunderstorms near Louisville.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Tupelo to Louisville?
The road trip is about 101.9 miles (164 km) and usually takes 02h 04m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
West Point is a useful midpoint, sitting about 51 miles from Tupelo and 50.9 miles from Louisville.
How much longer is the road route than the straight-line distance?
The direct path is about 80.9 miles (130.2 km), while the road route adds roughly 21 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM CDT. If you want a more comfortable same-day return, try to leave by 2:22 PM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $13.63 one way or $27.27 round trip. Estimated CO2 is about 32 kg one way.
What should you check before leaving?
Before you leave, expect Chance Showers And Thunderstorms around Tupelo and Chance Showers And Thunderstorms near Louisville.
Stop Ideas Near West Point
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to West Point.
Tuscaloosa
Flight Path Map
This map shows the direct air route between Tupelo and Louisville. Straight-line distance: 80.92 mi (130.23 km).
#1 Tupelo
City in and county seat of Lee County, Mississippi, United States
| Population | 38,303 |
| Coordinates | 34.2580700, -88.7046400 |
| Altitude | 85 |
| Country | United States |
#2 Louisville
City in Winston County, Mississippi, United States of America
| Population | 5,926 |
| Coordinates | 33.1237400, -89.0550600 |
| Altitude | 174 |
| Country | United States |
End: Louisville (-89.05506, 33.12374)
Estimated Travel Time
Distance: 164 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 03h 23m |
| 40 mph (64.37 km/h) | 02h 32m |
| 50 mph (80.47 km/h) | 02h 02m |
| 60 mph (96.56 km/h) | 01h 41m |
| 70 mph (112.65 km/h) | 01h 27m |
| 80 mph (129 km/h) | 01h 16m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.79 | $13.63 | $27.27 |
| Mid-grade | $4.26 | $15.33 | $30.66 |
| Premium | $4.63 | $16.65 | $33.30 |
| Diesel | $5.42 | $19.49 | $38.99 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Mississippi · May 31, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.