How far is Tupelo, MS from Clarksdale, MS?
The driving distance from Tupelo, MS to Clarksdale, MS is about 112.2 miles (180.6 km), with a travel time of about 02h 30m by car.
- The straight-line flight distance is about 106.7 miles (171.7 km).
- For a round trip, plan for roughly 05h 00m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM CDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 02h 30m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Lafayette County, Mississippi, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Partly Sunny
Driving Route Map
The map below follows the saved road route between Tupelo and Clarksdale.
Turn-by-Turn Driving Directions
Step-by-step road directions between Tupelo and Clarksdale.
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1
Start on North Spring Street
21 m · 8 sec · North Spring Street
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2
Turn left onto Court Street
85 m · 18 sec · Court Street
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3
Turn left onto North Broadway Street
91 m · 17 sec · North Broadway Street
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4
Turn right onto West Main Street
5.6 mi · 11 min · West Main Street
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5
Continue on Old Highway 6
5.6 mi · 8 min · Old Highway 6
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6
Take the ramp straight
2407 ft · 1 min
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7
Continue on Pontotoc Parkway East
11.2 mi · 13 min · Pontotoc Parkway East
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8
Keep slight right to continue on Pontotoc Parkway West
24.4 mi · 28 min · Pontotoc Parkway West
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9
Continue straight
2526 ft · 35 sec
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10
Continue straight
62.3 mi · 1 hr 23 min
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11
Continue on 4th Street
1.9 mi · 5 min · 4th Street
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12
Turn right
600 ft · 44 sec
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13
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between Tupelo and Clarksdale.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Pontotoc Parkway West
Continue straight
62.3 mi · 01h 23m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Sunny leaving Tupelo and Partly Sunny near Clarksdale.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Tupelo to Clarksdale?
The road trip is about 112.2 miles (180.6 km) and usually takes 02h 30m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Oxford is a useful midpoint, sitting about 56 miles from Tupelo and 56.2 miles from Clarksdale.
How much longer is the road route than the straight-line distance?
The direct path is about 106.7 miles (171.7 km), while the road route adds roughly 5.5 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM CDT. If you want a more comfortable same-day return, try to leave by 1:30 PM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $15.00 one way or $29.99 round trip. Estimated CO2 is about 35.2 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Tupelo and Partly Sunny near Clarksdale.
Stop Ideas Near Oxford
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Oxford.
Central Station
Greenwood
Flight Path Map
This map shows the direct air route between Tupelo and Clarksdale. Straight-line distance: 106.69 mi (171.7 km).
#1 Tupelo
City in and county seat of Lee County, Mississippi, United States
| Population | 38,303 |
| Coordinates | 34.2580700, -88.7046400 |
| Altitude | 85 |
| Country | United States |
#2 Clarksdale
City in Coahoma County, Mississippi, United States of America
| Population | 14,470 |
| Coordinates | 34.2001100, -90.5709300 |
| Altitude | 53 |
| Country | United States |
End: Clarksdale (-90.57093, 34.20011)
Estimated Travel Time
Distance: 181 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 03h 44m |
| 40 mph (64.37 km/h) | 02h 48m |
| 50 mph (80.47 km/h) | 02h 14m |
| 60 mph (96.56 km/h) | 01h 52m |
| 70 mph (112.65 km/h) | 01h 36m |
| 80 mph (129 km/h) | 01h 24m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.79 | $15.00 | $29.99 |
| Mid-grade | $4.26 | $16.87 | $33.73 |
| Premium | $4.63 | $18.32 | $36.63 |
| Diesel | $5.42 | $21.44 | $42.89 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Mississippi · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.