How far is Tupelo, MS from City of Greenville, MS?
The driving distance from Tupelo, MS to City of Greenville, MS is about 180.1 miles (289.8 km), with a travel time of about 03h 18m by car.
- The straight-line flight distance is about 147.6 miles (237.5 km).
- For a round trip, plan for roughly 06h 37m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 18m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Mississippi
Route Weather Snapshot
Check the forecast at both ends before you head out.
Rain Showers Likely
Chance Rain Showers then Partly Sunny
Driving Route Map
The map below follows the saved road route between Tupelo and City of Greenville.
Turn-by-Turn Driving Directions
Step-by-step road directions between Tupelo and City of Greenville.
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1
Start on North Spring Street
21 m · 8 sec · North Spring Street
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2
Turn left onto Court Street
85 m · 18 sec · Court Street
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3
Turn left onto North Broadway Street
91 m · 17 sec · North Broadway Street
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4
Turn right onto West Main Street
5.6 mi · 11 min · West Main Street
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5
Continue on Old Highway 6
5.6 mi · 8 min · Old Highway 6
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6
Take the ramp straight
2407 ft · 1 min
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7
Continue on Pontotoc Parkway East
11.2 mi · 13 min · Pontotoc Parkway East
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8
Keep slight right to continue on Pontotoc Parkway West
24.4 mi · 28 min · Pontotoc Parkway West
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9
Continue straight
2526 ft · 35 sec
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10
Continue straight
61.8 mi · 1 hr 22 min
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11
Take the exit slight left
64.9 mi · 1 hr 19 min
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12
Turn right onto Griffin Road
44 m · 7 sec · Griffin Road
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13
Turn left onto Old Hwy 61
1.3 km · 1 min · Old Hwy 61
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14
Turn straight onto North Broad Street
1.4 mi · 3 min · North Broad Street
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15
Turn right
7.8 mi · 11 min
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16
Turn left onto Martin Luther King Junior Boulevard
1 mi · 2 min · Martin Luther King Junior Boulevard
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17
Turn right onto East Reed Road
1.2 km · 1 min · East Reed Road
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18
Turn left onto Sandy Avenue
14 m · 2 sec · Sandy Avenue
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19
Arrive at your destination
0 m · 1 sec · Sandy Avenue
Car Route Details
A richer read on the saved driving route between Tupelo and City of Greenville.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Pontotoc Parkway West
Take the exit slight left
64.9 mi · 01h 19m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Rain Showers Likely leaving Tupelo and Chance Rain Showers then Partly Sunny near City of Greenville.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Tupelo to City of Greenville?
The road trip is about 180.1 miles (289.8 km) and usually takes 03h 18m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Marks is a useful midpoint, sitting about 93.1 miles from Tupelo and 87 miles from City of Greenville.
How much longer is the road route than the straight-line distance?
The direct path is about 147.6 miles (237.5 km), while the road route adds roughly 32.5 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 10:22 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $24.05 one way or $48.09 round trip. Estimated CO2 is about 56.4 kg one way.
What should you check before leaving?
Before you leave, expect Rain Showers Likely around Tupelo and Chance Rain Showers then Partly Sunny near City of Greenville.
Stop Ideas Near Marks
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Marks.
Greenwood
Central Station
Flight Path Map
This map shows the direct air route between Tupelo and City of Greenville. Straight-line distance: 147.59 mi (237.53 km).
#1 Tupelo
City in and county seat of Lee County, Mississippi, United States
| Population | 38,303 |
| Coordinates | 34.2580700, -88.7046400 |
| Altitude | 85 |
| Country | United States |
#2 City of Greenville
City in Washington County, Mississippi, United States
| Population | 30,686 |
| Coordinates | 33.3850200, -91.0514200 |
| Altitude | 40 |
| Country | United States |
End: Sandy Avenue (-91.051544, 33.385041)
Estimated Travel Time
Distance: 290 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 05h 59m |
| 40 mph (64.37 km/h) | 04h 30m |
| 50 mph (80.47 km/h) | 03h 36m |
| 60 mph (96.56 km/h) | 03h 00m |
| 70 mph (112.65 km/h) | 02h 34m |
| 80 mph (129 km/h) | 02h 14m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.79 | $24.05 | $48.09 |
| Mid-grade | $4.26 | $27.04 | $54.09 |
| Premium | $4.63 | $29.37 | $58.74 |
| Diesel | $5.42 | $34.39 | $68.77 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Mississippi · Apr 19, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.