How far is Tupelo, MS from Centreville, MS?
The driving distance from Tupelo, MS to Centreville, MS is about 310.3 miles (499.4 km), with a travel time of about 06h 15m by car.
- The straight-line flight distance is about 258.5 miles (416 km).
- For a round trip, plan for roughly 12h 30m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 06h 15m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Town in Leake County, Mississippi, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Rain Showers Likely
Showers And Thunderstorms Likely then Mostly Cloudy
Driving Route Map
The map below follows the saved road route between Tupelo and Centreville.
Turn-by-Turn Driving Directions
Step-by-step road directions between Tupelo and Centreville.
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1
Start on North Spring Street
21 m · 5 sec · North Spring Street
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2
Turn right onto Court Street
97 m · 16 sec · Court Street
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3
Turn right onto North Front Street
87 m · 15 sec · North Front Street
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4
Turn left onto East Main Street
2407 ft · 1 min · East Main Street
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5
Take the ramp straight
2248 ft · 56 sec
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6
Merge slight left onto Martin Luther King Drive
1.6 km · 1 min · Martin Luther King Drive
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7
Continue on Martin Luther King, Junior Drive
2.3 mi · 3 min · Martin Luther King, Junior Drive
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8
Continue on Martin Luther King Drive
7.7 mi · 9 min · Martin Luther King Drive
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9
Continue straight
1.4 mi · 2 min
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10
Continue straight
2.2 mi · 2 min
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11
Continue straight
1.5 mi · 2 min
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12
Continue straight
1.1 km · 49 sec
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13
Continue straight
1.4 mi · 2 min
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14
Continue on US Highway 45 Alternate
35.7 mi · 44 min · US Highway 45 Alternate
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15
Take the exit slight right toward US 82 West, MS 12 West, MS 25 South: Starkville
11.8 mi · 13 min
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16
Take the exit slight right toward MS 25 South: Louisville
5 mi · 7 min
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17
Continue straight
1.9 mi · 2 min
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18
Keep slight right
24.9 mi · 28 min
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19
Take the exit slight right
92.5 mi · 1 hr 46 min
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20
Take the exit slight right
1078 ft · 26 sec
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21
Merge slight left
6.1 mi · 8 min
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22
Keep slight left to continue on I 55 South: McComb, New Orleans
76 mi · 1 hr 21 min
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23
Take the exit slight right
1270 ft · 31 sec
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24
Keep slight right
629 ft · 15 sec
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25
Turn straight
20 mi · 30 min
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26
Turn left onto South Broad Street
15 mi · 26 min · South Broad Street
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27
Continue on East Howard Street
1.4 mi · 3 min · East Howard Street
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28
Turn left onto North Laurel Street
109 m · 12 sec · North Laurel Street
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29
Turn right onto East Main Street
1831 ft · 53 sec · East Main Street
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30
Arrive at your destination
0 m · 1 sec · West Main Street
Car Route Details
A richer read on the saved driving route between Tupelo and Centreville.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
MS 25 South
Take the exit slight right
92.5 mi · 01h 46m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Rain Showers Likely leaving Tupelo and Showers And Thunderstorms Likely then Mostly Cloudy near Centreville.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Tupelo to Centreville?
The road trip is about 310.3 miles (499.4 km) and usually takes 06h 15m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Lena is a useful midpoint, sitting about 155.3 miles from Tupelo and 155 miles from Centreville.
How much longer is the road route than the straight-line distance?
The direct path is about 258.5 miles (416 km), while the road route adds roughly 51.8 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM CDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $41.47 one way or $82.94 round trip. Estimated CO2 is about 97.3 kg one way.
What should you check before leaving?
Before you leave, expect Rain Showers Likely around Tupelo and Showers And Thunderstorms Likely then Mostly Cloudy near Centreville.
Stop Ideas Near Lena
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Lena.
Union Station
Yazoo City
Union Station
Hazlehurst station
Flight Path Map
This map shows the direct air route between Tupelo and Centreville. Straight-line distance: 258.48 mi (415.99 km).
#1 Tupelo
City in and county seat of Lee County, Mississippi, United States
| Population | 38,303 |
| Coordinates | 34.2580700, -88.7046400 |
| Altitude | 85 |
| Country | United States |
#2 Centreville
Town in Mississippi, United States
| Population | 1,392 |
| Coordinates | 31.0896200, -91.0684400 |
| Altitude | 117 |
| Country | United States |
End: Centreville (-91.06844, 31.08962)
Estimated Travel Time
Distance: 499 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 10h 20m |
| 40 mph (64.37 km/h) | 07h 45m |
| 50 mph (80.47 km/h) | 06h 12m |
| 60 mph (96.56 km/h) | 05h 10m |
| 70 mph (112.65 km/h) | 04h 26m |
| 80 mph (129 km/h) | 03h 52m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.79 | $41.47 | $82.94 |
| Mid-grade | $4.26 | $46.64 | $93.27 |
| Premium | $4.63 | $50.64 | $101.29 |
| Diesel | $5.42 | $59.29 | $118.59 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Mississippi · Apr 19, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.