How far is Tarkio, MO from O'Fallon, MO?
The driving distance from Tarkio, MO to O'Fallon, MO is about 337.3 miles (542.9 km), with a travel time of about 05h 27m by car.
- The straight-line flight distance is about 273.2 miles (439.6 km).
- For a round trip, plan for roughly 10h 54m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 27m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Human settlement in Lafayette County, Missouri, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Sunny
Driving Route Map
The map below follows the saved road route between Tarkio and O'Fallon.
Turn-by-Turn Driving Directions
Step-by-step road directions between Tarkio and O'Fallon.
-
1
Start on Main Street
48 m · 12 sec · Main Street
-
2
Turn left onto South 3rd Street
998 ft · 46 sec · South 3rd Street
-
3
Turn right onto Walnut Street
2617 ft · 52 sec · Walnut Street
-
4
At the end of the road, turn left onto South 10th Street
1.4 mi · 2 min · South 10th Street
-
5
Turn left
5.8 mi · 9 min
-
6
Turn left onto East Main Street
11.8 mi · 17 min · East Main Street
-
7
Take the ramp right toward I 29 South: Saint Joseph
2074 ft · 51 sec
-
8
Merge slight right
75.1 mi · 1 hr 21 min
-
9
Merge slight right
2.2 mi · 2 min
-
10
Keep slight right to continue on I 435 East: Saint Louis
28 mi · 31 min
-
11
Keep slight right to continue on I 70, US 24 West, US 40: Saint Louis, Kansas City, Sports Complex
1500 ft · 23 sec
-
12
Keep slight left to continue on I 70 East: Saint Louis
1.2 mi · 2 min
-
13
Keep slight left to continue on I 70 East: Saint Louis
143 m · 12 sec
-
14
Merge slight left onto George Brett Super Highway
2213 ft · 29 sec · George Brett Super Highway
-
15
Continue on Truman/Eisenhower Presidential Highway
2.9 mi · 3 min · Truman/Eisenhower Presidential Highway
-
16
Continue on Clifton J. Scott Memorial Highway
1.8 mi · 2 min · Clifton J. Scott Memorial Highway
-
17
Continue on Truman/Eisenhower Presidential Highway
2.6 mi · 3 min · Truman/Eisenhower Presidential Highway
-
18
Continue on Dwight D. Eisenhower Highway
52.5 mi · 57 min · Dwight D. Eisenhower Highway
-
19
Continue on U.S. Submarine Veterans' Memorial Highway
32 mi · 34 min · U.S. Submarine Veterans' Memorial Highway
-
20
Keep slight left to continue on U.S. Submarine Veterans' Memorial Highway
22.4 mi · 24 min · U.S. Submarine Veterans' Memorial Highway
-
21
Continue on Dwight D. Eisenhower Highway
1.8 mi · 2 min · Dwight D. Eisenhower Highway
-
22
Continue on Highway Patrol Sgt. Benjamin Booth Memorial Highway
1.6 mi · 2 min · Highway Patrol Sgt. Benjamin Booth Memorial Highway
-
23
Continue on Sheriff Roger I. Wilson Memorial Highway
1.9 mi · 2 min · Sheriff Roger I. Wilson Memorial Highway
-
24
Continue on Dwight D. Eisenhower Highway
88.2 mi · 1 hr 44 min · Dwight D. Eisenhower Highway
-
25
Take the exit slight right toward MO K: O'Fallon
1765 ft · 43 sec
-
26
Turn straight onto Drennen Parkway
46 m · 3 sec · Drennen Parkway
-
27
Keep slight right to continue on Drennen Parkway
51 m · 6 sec · Drennen Parkway
-
28
Turn slight left onto MO K: O'Fallon
19 m · 3 sec
-
29
Continue on South Main Street
3115 ft · 2 min · South Main Street
-
30
Turn right
8 m · 2 sec
-
31
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between Tarkio and O'Fallon.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Dwight D. Eisenhower Highway
Continue on Dwight D. Eisenhower Highway
88.2 mi · 01h 44m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Mostly Sunny leaving Tarkio and Sunny near O'Fallon.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Tarkio to O'Fallon?
The road trip is about 337.3 miles (542.9 km) and usually takes 05h 27m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Aullville is a useful midpoint, sitting about 168 miles from Tarkio and 169.3 miles from O'Fallon.
How much longer is the road route than the straight-line distance?
The direct path is about 273.2 miles (439.6 km), while the road route adds roughly 64.1 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 6:06 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $44.87 one way or $89.75 round trip. Estimated CO2 is about 105.8 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around Tarkio and Sunny near O'Fallon.
Stop Ideas Near Aullville
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Aullville.
Warrensburg
Sedalia
Lee's Summit
Independence
Flight Path Map
This map shows the direct air route between Tarkio and O'Fallon. Straight-line distance: 273.18 mi (439.64 km).
#1 Tarkio
City in Missouri
| Population | 1,420 |
| Coordinates | 40.4402800, -95.3777600 |
| Altitude | 283 |
| Country | United States |
#2 O'Fallon
The most populous city in St.
| Population | 89,769 |
| Coordinates | 38.8106100, -90.6998500 |
| Altitude | 165 |
| Country | United States |
End: (-90.699849, 38.810674)
Estimated Travel Time
Distance: 543 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 11h 14m |
| 40 mph (64.37 km/h) | 08h 26m |
| 50 mph (80.47 km/h) | 06h 44m |
| 60 mph (96.56 km/h) | 05h 37m |
| 70 mph (112.65 km/h) | 04h 49m |
| 80 mph (129 km/h) | 04h 12m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $44.87 | $89.75 |
| Mid-grade | $4.25 | $50.61 | $101.22 |
| Premium | $4.65 | $55.38 | $110.77 |
| Diesel | $5.30 | $63.12 | $126.24 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · May 13, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.