How far is Sistersville, WV from Martinsburg, WV?
The driving distance from Sistersville, WV to Martinsburg, WV is about 245.5 miles (395.1 km), with a travel time of about 04h 24m by car.
- The straight-line flight distance is about 161.8 miles (260.4 km).
- For a round trip, plan for roughly 08h 49m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 24m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Human settlement in Preston County, West Virginia, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Rain Showers
Chance Rain Showers
Driving Route Map
The map below follows the saved road route between Sistersville and Martinsburg.
Turn-by-Turn Driving Directions
Step-by-step road directions between Sistersville and Martinsburg.
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1
Start on Diamond Street
11 m · 7 sec · Diamond Street
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2
Turn left onto Wells Street
1.9 mi · 2 min · Wells Street
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3
Continue straight
7.5 mi · 9 min
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4
Turn right onto Mountaineer Highway
31.3 mi · 46 min · Mountaineer Highway
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5
At the end of the road, turn right onto Hornet Highway
3.4 mi · 4 min · Hornet Highway
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6
Continue on Husky Highway
9.3 mi · 11 min · Husky Highway
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7
Continue on Main Street
1.7 mi · 2 min · Main Street
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8
Continue on United States Highway 250
12.4 mi · 14 min · United States Highway 250
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9
Turn left onto Adams Street
769 ft · 16 sec · Adams Street
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10
Turn right onto Jefferson Street
1752 ft · 60 sec · Jefferson Street
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11
Turn left onto Merchant Street
1120 ft · 34 sec · Merchant Street
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12
Continue on East Park Avenue
1.6 km · 2 min · East Park Avenue
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13
Turn right onto Grafton Road
1921 ft · 56 sec · Grafton Road
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14
Take the ramp slight right
1007 ft · 25 sec
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15
Merge slight left onto Senator Jennings Randolph Highway
11.9 mi · 13 min · Senator Jennings Randolph Highway
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16
Take the exit slight right toward I 68 East: Cumberland
1779 ft · 43 sec
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17
Continue straight
112.3 mi · 2 hr 3 min
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18
Continue on Dwight D Eisenhower Highway
4.7 mi · 5 min · Dwight D Eisenhower Highway
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19
Continue on I 70, US 40 (Dwight D Eisenhower Highway)
3.3 mi · 4 min · I 70, US 40 (Dwight D Eisenhower Highway)
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20
Continue on Dwight D Eisenhower Highway
16.2 mi · 17 min · Dwight D Eisenhower Highway
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21
Take the exit slight right toward I 81: Roanoke, Harrisburg
629 ft · 15 sec
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22
Keep slight right to continue on I 81 South: Roanoke
2543 ft · 53 sec
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23
Merge slight left onto Maryland Veterans Memorial Highway
13.2 mi · 15 min · Maryland Veterans Memorial Highway
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24
Take the exit slight right toward WV 9 East
1925 ft · 47 sec
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25
Turn straight onto Hedgesville Road
2338 ft · 41 sec · Hedgesville Road
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26
Continue on Edwin Miller Boulevard
1.4 mi · 2 min · Edwin Miller Boulevard
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27
Continue on North Queen Street
1.2 mi · 2 min · North Queen Street
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28
Turn left onto East King Street
5 m · 1 sec · East King Street
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29
Arrive at your destination
0 m · 1 sec · East King Street
Car Route Details
A richer read on the saved driving route between Sistersville and Martinsburg.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 68 East
Continue straight
112 mi · 02h 03m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Chance Rain Showers leaving Sistersville and Chance Rain Showers near Martinsburg.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Sistersville to Martinsburg?
The road trip is about 245.5 miles (395.1 km) and usually takes 04h 24m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Brandonville is a useful midpoint, sitting about 117.7 miles from Sistersville and 127.8 miles from Martinsburg.
How much longer is the road route than the straight-line distance?
The direct path is about 161.8 miles (260.4 km), while the road route adds roughly 83.7 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 8:10 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $34.30 one way or $68.60 round trip. Estimated CO2 is about 77 kg one way.
What should you check before leaving?
Before you leave, expect Chance Rain Showers around Sistersville and Chance Rain Showers near Martinsburg.
Stop Ideas Near Brandonville
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Brandonville.
Connellsville station
Grantsville, MD
Frostburg, MD
Greensburg
Flight Path Map
This map shows the direct air route between Sistersville and Martinsburg. Straight-line distance: 161.79 mi (260.38 km).
#1 Sistersville
City in Tyler County, West Virginia, United States of America
| Population | 1,267 |
| Coordinates | 39.5642400, -80.9959400 |
| Altitude | 198 |
| Country | United States |
#2 Martinsburg
City in West Virginia, United States
| Population | 17,514 |
| Coordinates | 39.4562100, -77.9638900 |
| Altitude | 138 |
| Country | United States |
End: East King Street (-77.963854, 39.456185)
Estimated Travel Time
Distance: 395 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 08h 10m |
| 40 mph (64.37 km/h) | 06h 08m |
| 50 mph (80.47 km/h) | 04h 54m |
| 60 mph (96.56 km/h) | 04h 05m |
| 70 mph (112.65 km/h) | 03h 30m |
| 80 mph (129 km/h) | 03h 03m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.96 | $34.30 | $68.60 |
| Mid-grade | $4.43 | $38.36 | $76.71 |
| Premium | $4.78 | $41.38 | $82.75 |
| Diesel | $5.62 | $48.70 | $97.41 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in West Virginia · Apr 17, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.