How far is Seneca, PA from Reading, PA?
The driving distance from Seneca, PA to Reading, PA is about 266.4 miles (428.8 km), with a travel time of about 04h 43m by car.
- The straight-line flight distance is about 210.1 miles (338.1 km).
- For a round trip, plan for roughly 09h 27m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 43m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Census-designated place in Centre County, Pennsylvania
Route Weather Snapshot
Check the forecast at both ends before you head out.
Driving Route Map
The map below follows the saved road route between Seneca and Reading.
Turn-by-Turn Driving Directions
Step-by-step road directions between Seneca and Reading.
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1
Start on Pennsylvania Highway 257
2 mi · 4 min · Pennsylvania Highway 257
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2
Turn left onto Twenty-Eighth Division Highway
2.5 mi · 4 min · Twenty-Eighth Division Highway
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3
Continue on US Highway 322
12.4 mi · 18 min · US Highway 322
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4
Continue on Main Street
5.1 mi · 8 min · Main Street
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5
Continue on West Main Street
1.7 mi · 3 min · West Main Street
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6
Continue on Twenty-Eighth Division Highway
1.6 mi · 3 min · Twenty-Eighth Division Highway
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7
Continue on Main Street
1.6 km · 1 min · Main Street
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8
Continue on Route 322
4.1 mi · 6 min · Route 322
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9
Take the ramp slight right
1371 ft · 34 sec
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10
Merge slight left onto Keystone Shortway
153.1 mi · 2 hr 45 min · Keystone Shortway
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11
Take the exit slight right toward PA 54: Danville, Washingtonville
1080 ft · 27 sec
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12
Turn slight left
24 m · 3 sec
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13
Turn right onto Continental Boulevard
2.9 mi · 4 min · Continental Boulevard
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14
Continue on Factory Street
716 ft · 20 sec · Factory Street
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15
Continue on Danville-Riverside Bridge Road
1799 ft · 49 sec · Danville-Riverside Bridge Road
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16
Turn left onto Elysburg Road
9.7 mi · 11 min · Elysburg Road
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17
Continue on State Route 54
11.1 mi · 13 min · State Route 54
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18
Continue on Locust Gap Highway
1897 ft · 42 sec · Locust Gap Highway
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19
Continue on Fairgrounds Road
2.2 mi · 2 min · Fairgrounds Road
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20
Continue on Sunbury Road
9.4 mi · 11 min · Sunbury Road
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21
Continue on Sunbury Street
1.2 km · 1 min · Sunbury Street
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22
Turn right onto Pottsville Minersville Highway
1.8 mi · 2 min · Pottsville Minersville Highway
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23
Turn right onto Gordon Nagle Trail
4 mi · 7 min · Gordon Nagle Trail
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24
Continue on North Sillyman Street
1281 ft · 33 sec · North Sillyman Street
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25
Turn left onto Pottsville Street
1.1 km · 2 min · Pottsville Street
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26
Turn right onto Route 61 South
150 m · 6 sec · Route 61 South
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27
Continue on Center Avenue
10.6 mi · 13 min · Center Avenue
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28
Continue on Centre Street
4.2 mi · 6 min · Centre Street
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29
Continue on South 4th Street
1328 ft · 17 sec · South 4th Street
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30
Continue on Pottsville Pike
2.3 mi · 3 min · Pottsville Pike
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31
Continue on Shoemaker Avenue
3246 ft · 44 sec · Shoemaker Avenue
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32
Continue on Pottsville Pike
3.2 mi · 4 min · Pottsville Pike
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33
Continue on North Centre Avenue
1.6 km · 1 min · North Centre Avenue
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34
Continue on Pottsville Pike
4.7 mi · 6 min · Pottsville Pike
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35
Continue on Centre Avenue
2.8 mi · 4 min · Centre Avenue
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36
Continue on North 4th Street
1.3 km · 2 min · North 4th Street
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37
Turn left onto Franklin Street
1101 ft · 28 sec · Franklin Street
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38
Turn left onto South 6th Street
599 ft · 25 sec · South 6th Street
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39
Turn left onto Penn Street
85 m · 5 sec · Penn Street
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40
Arrive at your destination
0 m · 1 sec · Penn Street
Car Route Details
A richer read on the saved driving route between Seneca and Reading.
Straightforward drive
The saved road route has a manageable number of maneuvers and should be easy to follow with normal attention to signs.
Keystone Shortway
Merge slight left onto Keystone Shortway
153 mi · 02h 45m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Mostly Sunny leaving Seneca and Mostly Sunny near Reading.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Seneca to Reading?
The road trip is about 266.4 miles (428.8 km) and usually takes 04h 43m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Snydertown is a useful midpoint, sitting about 128.7 miles from Seneca and 137.7 miles from Reading.
How much longer is the road route than the straight-line distance?
The direct path is about 210.1 miles (338.1 km), while the road route adds roughly 56.3 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 7:32 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $41.96 one way or $83.92 round trip. Estimated CO2 is about 83.5 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around Seneca and Mostly Sunny near Reading.
Stop Ideas Near Snydertown
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Snydertown.
Lewistown
Tyrone
Huntingdon
Altoona Transportation Center
Flight Path Map
This map shows the direct air route between Seneca and Reading. Straight-line distance: 210.1 mi (338.13 km).
#1 Seneca
Situated in the northwestern region of Pennsylvania, this census-designated place lies within Venango County at an elevation of approximately 1,453 feet above sea level.
| Population | 0 |
| Coordinates | 41.3786700, -79.7039400 |
| Altitude | 443 |
| Country | United States |
#2 Reading
The fourth most populous city in Pennsylvania.
| Population | 88,217 |
| Coordinates | 40.3356500, -75.9268700 |
| Altitude | 93 |
| Country | United States |
End: Penn Street (-75.926876, 40.335365)
Estimated Travel Time
Distance: 429 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 08h 52m |
| 40 mph (64.37 km/h) | 06h 39m |
| 50 mph (80.47 km/h) | 05h 19m |
| 60 mph (96.56 km/h) | 04h 26m |
| 70 mph (112.65 km/h) | 03h 48m |
| 80 mph (129 km/h) | 03h 19m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.46 | $41.96 | $83.92 |
| Mid-grade | $4.93 | $46.30 | $92.59 |
| Premium | $5.31 | $49.87 | $99.73 |
| Diesel | $6.55 | $61.57 | $123.14 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Pennsylvania · Oct 15, 2026