How far is Saint Charles, MO from Glendale, MO?
The driving distance from Saint Charles, MO to Glendale, MO is about 204.2 miles (328.6 km), with a travel time of about 04h 05m by car.
- The straight-line flight distance is about 167 miles (268.7 km).
- For a round trip, plan for roughly 08h 11m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 05m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Village in the United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Driving Route Map
The map below follows the saved road route between Saint Charles and Glendale.
Turn-by-Turn Driving Directions
Step-by-step road directions between Saint Charles and Glendale.
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1
Start on North Second Street
949 ft · 38 sec · North Second Street
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2
Turn right onto Jefferson Street
1093 ft · 45 sec · Jefferson Street
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3
Turn left onto South Fifth Street
1.1 mi · 3 min · South Fifth Street
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4
Take the ramp slight left toward I 70 East
1019 ft · 14 sec
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5
Merge slight left
2.7 mi · 3 min
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6
Take the exit slight right toward I 270: Chicago, Memphis
872 ft · 12 sec
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7
Keep slight right to continue on I 270 South: Memphis
2339 ft · 33 sec
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8
Continue on I 270 South: Memphis
723 ft · 10 sec
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9
Merge slight left
19 mi · 24 min
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10
Take the exit slight right toward I 55, US 61, US 67: Saint Louis, Memphis, Lemay Ferry Road
1911 ft · 27 sec
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11
Keep slight right to continue on I 55 South: Memphis
2031 ft · 44 sec
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12
Merge slight left onto Rosa Parks Highway
1.5 mi · 2 min · Rosa Parks Highway
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13
Continue on Officer Thomas G. Smith, Jr. Memorial Highway
1.8 mi · 2 min · Officer Thomas G. Smith, Jr. Memorial Highway
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14
Continue on Police Officer Steven Jarvis Memorial Highway
160.1 mi · 2 hr 52 min · Police Officer Steven Jarvis Memorial Highway
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15
Take the exit slight right toward MO 162: Portageville
1184 ft · 25 sec
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16
Turn right
3079 ft · 54 sec
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17
Turn right
1 mi · 2 min
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18
Turn left
9.8 mi · 17 min
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19
Turn left onto County Road 277
1.1 mi · 4 min · County Road 277
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20
Turn right onto County Road 281
1.7 mi · 7 min · County Road 281
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21
Turn right onto County Road 282
1 mi · 4 min · County Road 282
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22
Continue straight
2310 ft · 1 min
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23
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between Saint Charles and Glendale.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Police Officer Steven Jarvis Memorial Highway
Continue on Police Officer Steven Jarvis Memorial Highway
160 mi · 02h 52m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Sunny leaving Saint Charles and Sunny near Glendale.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Saint Charles to Glendale?
The road trip is about 204.2 miles (328.6 km) and usually takes 04h 05m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Old Appleton is a useful midpoint, sitting about 102.2 miles from Saint Charles and 102 miles from Glendale.
How much longer is the road route than the straight-line distance?
The direct path is about 167 miles (268.7 km), while the road route adds roughly 37.2 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 8:48 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $27.19 one way or $54.38 round trip. Estimated CO2 is about 64.1 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Saint Charles and Sunny near Glendale.
Stop Ideas Near Old Appleton
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Old Appleton.
Carbondale station
Du Quoin
Marion, IL
Vienna, IL
Flight Path Map
This map shows the direct air route between Saint Charles and Glendale. Straight-line distance: 166.98 mi (268.73 km).
#1 Saint Charles
A city in St.
| Population | 71,761 |
| Coordinates | 38.7839400, -90.4812300 |
| Altitude | 147 |
| Country | United States |
#2 Glendale
City in Missouri
| Population | 5,863 |
| Coordinates | 36.4106200, -89.9056400 |
| Altitude | 82 |
| Country | United States |
End: Glendale (-89.90564, 36.41062)
Estimated Travel Time
Distance: 329 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 06h 48m |
| 40 mph (64.37 km/h) | 05h 06m |
| 50 mph (80.47 km/h) | 04h 05m |
| 60 mph (96.56 km/h) | 03h 24m |
| 70 mph (112.65 km/h) | 02h 55m |
| 80 mph (129 km/h) | 02h 32m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $27.19 | $54.38 |
| Mid-grade | $4.25 | $30.66 | $61.33 |
| Premium | $4.65 | $33.56 | $67.11 |
| Diesel | $5.30 | $38.24 | $76.48 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Apr 19, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.