How far is Saint Charles, MO from Buffalo, MO?
The driving distance from Saint Charles, MO to Buffalo, MO is about 192.1 miles (309.2 km), with a travel time of about 03h 47m by car.
- The straight-line flight distance is about 162.2 miles (261 km).
- For a round trip, plan for roughly 07h 34m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 47m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Phelps County, Missouri, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Mostly Sunny
Driving Route Map
The map below follows the saved road route between Saint Charles and Buffalo.
Turn-by-Turn Driving Directions
Step-by-step road directions between Saint Charles and Buffalo.
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1
Start on North Second Street
949 ft · 38 sec · North Second Street
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2
Turn right onto Jefferson Street
1093 ft · 45 sec · Jefferson Street
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3
Turn left onto South Fifth Street
1.1 mi · 3 min · South Fifth Street
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4
Take the ramp slight left toward I 70 East
1019 ft · 14 sec
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5
Merge slight left
2.7 mi · 3 min
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6
Take the exit slight right toward I 270: Chicago, Memphis
872 ft · 12 sec
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7
Keep slight right to continue on I 270 South: Memphis
2339 ft · 33 sec
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8
Continue on I 270 South: Memphis
723 ft · 10 sec
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9
Merge slight left
10.9 mi · 14 min
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10
Take the exit slight right toward Dougherty Ferry Road
1331 ft · 28 sec
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11
Turn right onto Dougherty Ferry Road
2.5 mi · 5 min · Dougherty Ferry Road
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12
Continue on Forest Avenue
1.6 km · 2 min · Forest Avenue
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13
Turn left
1.2 km · 1 min
-
14
Take the exit slight right
32 m · 3 sec
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15
Turn right onto North Highway Drive
748 ft · 14 sec · North Highway Drive
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16
Take the ramp straight toward I 44 West, US 50 West: Rolla
936 ft · 13 sec
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17
Merge slight left onto Henry Shaw Ozark Corridor
143 mi · 2 hr 35 min · Henry Shaw Ozark Corridor
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18
Take the exit slight right toward MO 32, MO 5, MO 64: Hartville
932 ft · 20 sec
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19
Turn right onto South Jefferson Avenue
1 mi · 2 min · South Jefferson Avenue
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20
Turn left onto West Commercial Street
4.3 mi · 7 min · West Commercial Street
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21
Continue straight
22.6 mi · 31 min
-
22
Turn right onto South Maple Street
1350 ft · 27 sec · South Maple Street
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23
Arrive at your destination
0 m · 1 sec · South Maple Street
Car Route Details
A richer read on the saved driving route between Saint Charles and Buffalo.
Interchange-aware route
The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.
Henry Shaw Ozark Corridor
Merge slight left onto Henry Shaw Ozark Corridor
143 mi · 02h 35m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Mostly Sunny leaving Saint Charles and Mostly Sunny near Buffalo.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Saint Charles to Buffalo?
The road trip is about 192.1 miles (309.2 km) and usually takes 03h 47m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Saint James is a useful midpoint, sitting about 96 miles from Saint Charles and 96.2 miles from Buffalo.
How much longer is the road route than the straight-line distance?
The direct path is about 162.2 miles (261 km), while the road route adds roughly 29.9 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 9:26 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $25.57 one way or $51.13 round trip. Estimated CO2 is about 60.3 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around Saint Charles and Mostly Sunny near Buffalo.
Stop Ideas Near Saint James
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Saint James.
Jefferson City
Hermann
Washington
Flight Path Map
This map shows the direct air route between Saint Charles and Buffalo. Straight-line distance: 162.16 mi (260.97 km).
#1 Saint Charles
A city in St.
| Population | 71,761 |
| Coordinates | 38.7839400, -90.4812300 |
| Altitude | 147 |
| Country | United States |
#2 Buffalo
City in Dallas County, Missouri, United States
| Population | 3,202 |
| Coordinates | 37.6439300, -93.0924100 |
| Altitude | 366 |
| Country | United States |
End: Buffalo (-93.09241, 37.64393)
Estimated Travel Time
Distance: 309 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 06h 24m |
| 40 mph (64.37 km/h) | 04h 48m |
| 50 mph (80.47 km/h) | 03h 50m |
| 60 mph (96.56 km/h) | 03h 12m |
| 70 mph (112.65 km/h) | 02h 44m |
| 80 mph (129 km/h) | 02h 23m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $25.57 | $51.13 |
| Mid-grade | $4.25 | $28.84 | $57.67 |
| Premium | $4.65 | $31.55 | $63.11 |
| Diesel | $5.30 | $35.96 | $71.92 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · May 01, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.