How far is Pittsburgh, PA from Sayre, PA?
The driving distance from Pittsburgh, PA to Sayre, PA is about 280.1 miles (450.8 km), with a travel time of about 05h 51m by car.
- The straight-line flight distance is about 209.8 miles (337.6 km).
- For a round trip, plan for roughly 11h 43m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 51m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Census designated place
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Driving Route Map
The map below follows the saved road route between Pittsburgh and Sayre.
Turn-by-Turn Driving Directions
Step-by-step road directions between Pittsburgh and Sayre.
-
1
Start on Grant Street
14 m · 9 sec · Grant Street
-
2
Continue on Grant Street
1539 ft · 1 min · Grant Street
-
3
Take the ramp slight right toward I 376 East: Monroeville
2054 ft · 51 sec
-
4
Merge slight right onto Penn-Lincoln Parkway East
13.8 mi · 19 min · Penn-Lincoln Parkway East
-
5
Merge slight left onto William Penn Highway
44.8 mi · 1 hr 6 min · William Penn Highway
-
6
Continue on Admiral Peary Highway
13.7 mi · 20 min · Admiral Peary Highway
-
7
Continue on William Penn Highway
16.8 mi · 20 min · William Penn Highway
-
8
Continue on I 99, US 220: Altoona, Bedford
2680 ft · 45 sec
-
9
Keep slight left to continue on I 99 North, US 220 North: Altoona
1.4 km · 1 min
-
10
Merge slight left
41 mi · 45 min
-
11
Keep slight left
4 mi · 5 min
-
12
Keep slight left to continue on I 99 North, US 220 North: Bellefonte
12.3 mi · 15 min
-
13
Turn left onto I 80 East, US 220 North: Williamsport
1283 ft · 31 sec
-
14
Merge slight left onto Keystone Shortway
12.3 mi · 13 min · Keystone Shortway
-
15
Take the exit slight right toward PA 64: Pleasant Gap, Mill Hall
2074 ft · 54 sec
-
16
Turn left onto Nittany Valley Drive
4.5 mi · 8 min · Nittany Valley Drive
-
17
Turn right onto Long Run Road
105 m · 7 sec · Long Run Road
-
18
Take the ramp slight right
1182 ft · 40 sec
-
19
Turn sharp left onto Frank D O'Reilly Jr Highway
5.7 mi · 7 min · Frank D O'Reilly Jr Highway
-
20
Continue on Appalachian Thwy
1369 ft · 18 sec · Appalachian Thwy
-
21
Continue on Appalachian Thruway
10.4 mi · 12 min · Appalachian Thruway
-
22
Continue on Susquehanna Beltway
25 mi · 30 min · Susquehanna Beltway
-
23
Take the exit slight right toward US 220 north: Halls, Pennsdale
1331 ft · 33 sec
-
24
Turn left onto Lycoming Mall Drive
5 mi · 6 min · Lycoming Mall Drive
-
25
Turn left
64.1 mi · 1 hr 14 min
-
26
Turn right
2.5 mi · 4 min
-
27
Turn right onto East Pine Street
615 ft · 22 sec · East Pine Street
-
28
Turn left onto South Elmer Avenue
1.3 km · 2 min · South Elmer Avenue
-
29
Turn right onto West Hayden Street
148 m · 21 sec · West Hayden Street
-
30
Arrive at your destination
0 m · 1 sec · West Hayden Street
Car Route Details
A richer read on the saved driving route between Pittsburgh and Sayre.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Longest stretch
Turn left
64.1 mi · 01h 14m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Sunny leaving Pittsburgh and Mostly Sunny near Sayre.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Pittsburgh to Sayre?
The road trip is about 280.1 miles (450.8 km) and usually takes 05h 51m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Houserville is a useful midpoint, sitting about 139.9 miles from Pittsburgh and 140.2 miles from Sayre.
How much longer is the road route than the straight-line distance?
The direct path is about 209.8 miles (337.6 km), while the road route adds roughly 70.3 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 5:16 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $40.41 one way or $80.82 round trip. Estimated CO2 is about 87.9 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Pittsburgh and Mostly Sunny near Sayre.
Stop Ideas Near Houserville
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Houserville.
Lewistown
Tyrone
Huntingdon
Altoona Transportation Center
Flight Path Map
This map shows the direct air route between Pittsburgh and Sayre. Straight-line distance: 209.79 mi (337.63 km).
#1 Pittsburgh
The second most populous city in Pennsylvania and the center of the Pittsburgh metropolitan area.
| Population | 299,226 |
| Coordinates | 40.4406200, -79.9958900 |
| Altitude | 233 |
| Country | United States |
#2 Sayre
City in Oklahoma
| Population | 5,338 |
| Coordinates | 41.9789600, -76.5155000 |
| Altitude | 235 |
| Country | United States |
End: Sayre (-76.5155, 41.97896)
Estimated Travel Time
Distance: 451 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 09h 20m |
| 40 mph (64.37 km/h) | 07h 00m |
| 50 mph (80.47 km/h) | 05h 36m |
| 60 mph (96.56 km/h) | 04h 40m |
| 70 mph (112.65 km/h) | 04h 00m |
| 80 mph (129 km/h) | 03h 29m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.09 | $40.41 | $80.82 |
| Mid-grade | $4.60 | $45.48 | $90.97 |
| Premium | $4.95 | $49.00 | $97.99 |
| Diesel | $5.98 | $59.14 | $118.28 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Pennsylvania · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.