How far is Philadelphia, PA from Knox, PA?
The driving distance from Philadelphia, PA to Knox, PA is about 320.7 miles (516.1 km), with a travel time of about 06h 00m by car.
- The straight-line flight distance is about 245.9 miles (395.8 km).
- For a round trip, plan for roughly 12h 01m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 06h 00m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Township in northeastern Union County, Pennsylvania
Route Weather Snapshot
Check the forecast at both ends before you head out.
Driving Route Map
The map below follows the saved road route between Philadelphia and Knox.
Turn-by-Turn Driving Directions
Step-by-step road directions between Philadelphia and Knox.
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1
Start on South Penn Square
121 m · 9 sec · South Penn Square
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2
Keep slight left to continue on East Penn Square
737 ft · 19 sec · East Penn Square
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3
Continue on John F. Kennedy Boulevard
803 ft · 21 sec · John F. Kennedy Boulevard
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4
Turn right onto North 16th Street
2132 ft · 55 sec · North 16th Street
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5
Take the ramp slight right toward I 676 West, US 30 West: International Airport, Valley Forge
1091 ft · 27 sec
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6
Merge slight left onto Vine Street Expressway
1 mi · 2 min · Vine Street Expressway
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7
Merge slight right onto Schuylkill Expressway
12.1 mi · 17 min · Schuylkill Expressway
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8
Take the exit slight right toward I 476 North: Plymouth Meeting
3232 ft · 1 min
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9
Merge slight left onto Mid-County Expressway
3.3 mi · 4 min · Mid-County Expressway
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10
Turn slight left onto Mid-County Expressway
885 ft · 14 sec · Mid-County Expressway
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11
Continue on Pennsylvania Turnpike Northeast Extension
75 mi · 1 hr 21 min · Pennsylvania Turnpike Northeast Extension
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12
Take the exit slight right toward PA 940, I 80: Hazleton, Mount Pocono
1.1 km · 2 min
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13
Keep slight left
879 ft · 24 sec
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14
Keep slight right to continue on I 80 West: Hazleton
1650 ft · 40 sec
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15
Merge slight left onto Keystone Shortway
222.2 mi · 4 hr 1 min · Keystone Shortway
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16
Take the exit slight right toward PA 338: Knox
2320 ft · 1 min
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17
Keep slight right to continue on PA 338: Knox
49 m · 5 sec
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18
Turn right onto Canoe Ripple Road
2670 ft · 1 min · Canoe Ripple Road
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19
At the end of the road, turn right
1.6 mi · 3 min
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20
Turn left onto Knox Road
1 mi · 2 min · Knox Road
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21
Continue on South Main Street
2456 ft · 1 min · South Main Street
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22
Arrive at your destination
0 m · 1 sec · Main Street
Car Route Details
A richer read on the saved driving route between Philadelphia and Knox.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Keystone Shortway
Merge slight left onto Keystone Shortway
222 mi · 04h 01m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Sunny leaving Philadelphia and Sunny near Knox.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Philadelphia to Knox?
The road trip is about 320.7 miles (516.1 km) and usually takes 06h 00m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
White Deer is a useful midpoint, sitting about 160.1 miles from Philadelphia and 160.5 miles from Knox.
How much longer is the road route than the straight-line distance?
The direct path is about 245.9 miles (395.8 km), while the road route adds roughly 74.8 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM EDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $46.21 one way or $92.43 round trip. Estimated CO2 is about 100.5 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Philadelphia and Sunny near Knox.
Stop Ideas Near White Deer
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to White Deer.
Lewistown
Wilkes-Barre, PA
Harrisburg Transportation Center
White Haven, PA
Flight Path Map
This map shows the direct air route between Philadelphia and Knox. Straight-line distance: 245.93 mi (395.78 km).
#1 Philadelphia
The sixth most populous city in the United States and the center of the Philadelphia metropolitan area.
| Population | 1,578,487 |
| Coordinates | 39.9523300, -75.1637900 |
| Altitude | 12 |
| Country | United States |
#2 Knox
Borough of Pennsylvania
| Population | 1,067 |
| Coordinates | 41.2345100, -79.5372700 |
| Altitude | 424 |
| Country | United States |
End: Knox (-79.53727, 41.23451)
Estimated Travel Time
Distance: 516 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 10h 41m |
| 40 mph (64.37 km/h) | 08h 01m |
| 50 mph (80.47 km/h) | 06h 24m |
| 60 mph (96.56 km/h) | 05h 20m |
| 70 mph (112.65 km/h) | 04h 34m |
| 80 mph (129 km/h) | 04h 00m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.09 | $46.21 | $92.43 |
| Mid-grade | $4.60 | $52.01 | $104.03 |
| Premium | $4.95 | $56.03 | $112.06 |
| Diesel | $5.98 | $67.63 | $135.27 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Pennsylvania · May 18, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.