How far is O'Fallon, MO from Nixa, MO?
The driving distance from O'Fallon, MO to Nixa, MO is about 222.7 miles (358.4 km), with a travel time of about 04h 22m by car.
- The straight-line flight distance is about 186.8 miles (300.6 km).
- For a round trip, plan for roughly 08h 45m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 22m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
This departure sits inside the recommended comfort window for the route.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Phelps County, Missouri, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Driving Route Map
The map below follows the saved road route between O'Fallon and Nixa.
Turn-by-Turn Driving Directions
Step-by-step road directions between O'Fallon and Nixa.
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1
Start on the route
8 m · 7 sec
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2
Turn left onto South Main Street
2865 ft · 1 min · South Main Street
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3
Continue straight
3.1 mi · 6 min
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4
Continue straight
3.4 mi · 5 min
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5
Take the ramp slight right toward I 64 East, US 40 East, US 61 South
1523 ft · 22 sec
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6
Merge slight left onto Avenue of the Saints
3.7 mi · 5 min · Avenue of the Saints
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7
Take the exit slight right toward Chesterfield Airport Road
2700 ft · 58 sec
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8
Continue on Chesterfield Airport Road
110 m · 7 sec · Chesterfield Airport Road
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9
Turn right onto Olive Street Road
64 m · 5 sec
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10
Turn right onto Olive Street Road
1.5 km · 2 min · Olive Street Road
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11
Continue on North Eatherton Road
2.4 mi · 5 min · North Eatherton Road
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12
Enter the roundabout and take exit 2 toward the route
21 m · 1 sec
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13
Exit the roundabout
4.3 mi · 7 min
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14
Enter the roundabout and take exit 2 toward the route
29 m · 2 sec
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15
Exit the roundabout
2098 ft · 45 sec
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16
Enter the roundabout and take exit 2 toward MO 100 West: Gray Summit
23 m · 2 sec
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17
Exit the roundabout onto MO 100 West: Gray Summit
1202 ft · 33 sec
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18
Merge slight left
13.3 mi · 19 min
-
19
Take the exit slight right toward I 44 West, US 50 West: St. Clair
1157 ft · 14 sec
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20
Merge slight left
170.7 mi · 3 hr 4 min
-
21
Take the exit slight right toward US 65 South: Branson
1412 ft · 48 sec
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22
Merge slight left onto Schoolcraft Freeway
11 mi · 14 min · Schoolcraft Freeway
-
23
Continue on American Legion Memorial Highway
1.4 mi · 2 min · American Legion Memorial Highway
-
24
Take the exit slight right toward MO J, MO CC: Fremont Hills
1112 ft · 27 sec
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25
Turn straight
1.4 km · 2 min
-
26
Turn left onto Fremont Road
1.5 mi · 2 min · Fremont Road
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27
Turn right onto East North Road
1 mi · 2 min · East North Road
-
28
Turn left onto North Cheyenne Road
3150 ft · 1 min · North Cheyenne Road
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29
At the end of the road, turn right
1.7 mi · 3 min
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30
Turn left
18 m · 4 sec
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31
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between O'Fallon and Nixa.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 44 West
Merge slight left
171 mi · 03h 04m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Sunny leaving O'Fallon and Mostly Sunny near Nixa.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from O'Fallon to Nixa?
The road trip is about 222.7 miles (358.4 km) and usually takes 04h 22m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Newburg is a useful midpoint, sitting about 111.3 miles from O'Fallon and 111.4 miles from Nixa.
How much longer is the road route than the straight-line distance?
The direct path is about 186.8 miles (300.6 km), while the road route adds roughly 35.9 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 8:14 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $29.64 one way or $59.28 round trip. Estimated CO2 is about 69.9 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around O'Fallon and Mostly Sunny near Nixa.
Stop Ideas Near Newburg
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Newburg.
Jefferson City
Hermann
Washington
Flight Path Map
This map shows the direct air route between O'Fallon and Nixa. Straight-line distance: 186.81 mi (300.64 km).
#1 O'Fallon
The most populous city in St.
| Population | 89,769 |
| Coordinates | 38.8106100, -90.6998500 |
| Altitude | 165 |
| Country | United States |
#2 Nixa
City in Christian County, Missouri
| Population | 23,330 |
| Coordinates | 37.0433900, -93.2943500 |
| Altitude | 395 |
| Country | United States |
End: Nixa (-93.29435, 37.04339)
Estimated Travel Time
Distance: 358 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 07h 25m |
| 40 mph (64.37 km/h) | 05h 34m |
| 50 mph (80.47 km/h) | 04h 27m |
| 60 mph (96.56 km/h) | 03h 42m |
| 70 mph (112.65 km/h) | 03h 10m |
| 80 mph (129 km/h) | 02h 46m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $29.64 | $59.28 |
| Mid-grade | $4.25 | $33.43 | $66.86 |
| Premium | $4.65 | $36.58 | $73.16 |
| Diesel | $5.30 | $41.69 | $83.38 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Apr 25, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.