How far is O'Fallon, MO from Buffalo, MO?
The driving distance from O'Fallon, MO to Buffalo, MO is about 185.8 miles (299 km), with a travel time of about 03h 46m by car.
- The straight-line flight distance is about 152.9 miles (246 km).
- For a round trip, plan for roughly 07h 33m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 46m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Phelps County, Missouri, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Mostly Sunny
Driving Route Map
The map below follows the saved road route between O'Fallon and Buffalo.
Turn-by-Turn Driving Directions
Step-by-step road directions between O'Fallon and Buffalo.
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1
Start on the route
8 m · 7 sec
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2
Turn left onto South Main Street
2865 ft · 1 min · South Main Street
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3
Continue straight
3.1 mi · 6 min
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4
Continue straight
3.4 mi · 5 min
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5
Take the ramp slight right toward I 64 East, US 40 East, US 61 South
1523 ft · 22 sec
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6
Merge slight left onto Avenue of the Saints
3.7 mi · 5 min · Avenue of the Saints
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7
Take the exit slight right toward Chesterfield Airport Road
2700 ft · 58 sec
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8
Continue on Chesterfield Airport Road
110 m · 7 sec · Chesterfield Airport Road
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9
Turn right onto Olive Street Road
64 m · 5 sec
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10
Turn right onto Olive Street Road
1.5 km · 2 min · Olive Street Road
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11
Continue on North Eatherton Road
2.4 mi · 5 min · North Eatherton Road
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12
Enter the roundabout and take exit 2 toward the route
21 m · 1 sec
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13
Exit the roundabout
4.3 mi · 7 min
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14
Enter the roundabout and take exit 2 toward the route
29 m · 2 sec
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15
Exit the roundabout
2098 ft · 45 sec
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16
Enter the roundabout and take exit 2 toward MO 100 West: Gray Summit
23 m · 2 sec
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17
Exit the roundabout onto MO 100 West: Gray Summit
1202 ft · 33 sec
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18
Merge slight left
13.3 mi · 19 min
-
19
Take the exit slight right toward I 44 West, US 50 West: St. Clair
1157 ft · 14 sec
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20
Merge slight left
124 mi · 2 hr 13 min
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21
Take the exit slight right toward MO 32, MO 5, MO 64: Hartville
932 ft · 20 sec
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22
Turn right onto South Jefferson Avenue
1 mi · 2 min · South Jefferson Avenue
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23
Turn left onto West Commercial Street
4.3 mi · 7 min · West Commercial Street
-
24
Continue straight
22.6 mi · 31 min
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25
Turn right onto South Maple Street
1350 ft · 27 sec · South Maple Street
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26
Arrive at your destination
0 m · 1 sec · South Maple Street
Car Route Details
A richer read on the saved driving route between O'Fallon and Buffalo.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 44 West
Merge slight left
124 mi · 02h 13m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Mostly Sunny leaving O'Fallon and Mostly Sunny near Buffalo.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from O'Fallon to Buffalo?
The road trip is about 185.8 miles (299 km) and usually takes 03h 46m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Saint James is a useful midpoint, sitting about 92.8 miles from O'Fallon and 93 miles from Buffalo.
How much longer is the road route than the straight-line distance?
The direct path is about 152.9 miles (246 km), while the road route adds roughly 32.9 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 9:26 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $24.74 one way or $49.48 round trip. Estimated CO2 is about 58.3 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around O'Fallon and Mostly Sunny near Buffalo.
Stop Ideas Near Saint James
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Saint James.
Jefferson City
Hermann
Washington
Flight Path Map
This map shows the direct air route between O'Fallon and Buffalo. Straight-line distance: 152.84 mi (245.97 km).
#1 O'Fallon
The most populous city in St.
| Population | 89,769 |
| Coordinates | 38.8106100, -90.6998500 |
| Altitude | 165 |
| Country | United States |
#2 Buffalo
City in Dallas County, Missouri, United States
| Population | 3,202 |
| Coordinates | 37.6439300, -93.0924100 |
| Altitude | 366 |
| Country | United States |
End: Buffalo (-93.09241, 37.64393)
Estimated Travel Time
Distance: 299 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 06h 11m |
| 40 mph (64.37 km/h) | 04h 38m |
| 50 mph (80.47 km/h) | 03h 42m |
| 60 mph (96.56 km/h) | 03h 05m |
| 70 mph (112.65 km/h) | 02h 39m |
| 80 mph (129 km/h) | 02h 19m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $24.74 | $49.48 |
| Mid-grade | $4.25 | $27.90 | $55.80 |
| Premium | $4.65 | $30.53 | $61.06 |
| Diesel | $5.30 | $34.79 | $69.59 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · May 01, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.