How far is Nogales, AZ from Mesa, AZ?
The driving distance from Nogales, AZ to Mesa, AZ is about 180.6 miles (290.6 km), with a travel time of about 02h 45m by car.
- The straight-line flight distance is about 152.9 miles (246.1 km).
- For a round trip, plan for roughly 05h 31m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM MST.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 02h 45m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Town in Pima and Pinal counties in Arizona, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Partly Sunny
Driving Route Map
The map below follows the saved road route between Nogales and Mesa.
Turn-by-Turn Driving Directions
Step-by-step road directions between Nogales and Mesa.
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1
Start on North Wayside Drive
28 m · 5 sec · North Wayside Drive
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2
Turn right onto North Morley Avenue
1374 ft · 1 min · North Morley Avenue
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3
Turn left
39 m · 9 sec
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4
Turn right onto North Grand Avenue
1.8 mi · 3 min · North Grand Avenue
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5
Turn left onto West Mariposa Road
1.2 km · 1 min · West Mariposa Road
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6
Take the ramp right toward I 19 North: Tucson
1491 ft · 37 sec
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7
Merge slight left onto Nogales–Tucson Highway
60 mi · 1 hr 6 min · Nogales–Tucson Highway
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8
Keep slight left to continue on I 10 West: Phoenix
3178 ft · 49 sec
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9
Merge slight left onto South Freeway
5.4 mi · 6 min · South Freeway
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10
Continue on Casa Grande-Tucson Highway
3.7 mi · 4 min · Casa Grande-Tucson Highway
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11
Keep slight left to continue on Casa Grande-Tucson Highway
50.7 mi · 51 min · Casa Grande-Tucson Highway
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12
Continue on Phoenix-Casa Grande Highway
24.1 mi · 24 min · Phoenix-Casa Grande Highway
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13
Take the exit slight right toward AZ 587 North: Chandler, Gilbert
1404 ft · 54 sec
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14
Turn left
5.8 mi · 9 min
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15
Continue on South Arizona Avenue
11 mi · 19 min · South Arizona Avenue
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16
Continue on South Country Club Drive
4 mi · 7 min · South Country Club Drive
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17
Turn right onto West University Drive
1.6 km · 2 min · West University Drive
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18
Arrive at your destination
0 m · 1 sec · East University Drive
Car Route Details
A richer read on the saved driving route between Nogales and Mesa.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Nogales–Tucson Highway
Merge slight left onto Nogales–Tucson Highway
60 mi · 01h 06m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Mostly Sunny leaving Nogales and Partly Sunny near Mesa.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Nogales to Mesa?
The road trip is about 180.6 miles (290.6 km) and usually takes 02h 45m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Marana is a useful midpoint, sitting about 85 miles from Nogales and 95.6 miles from Mesa.
How much longer is the road route than the straight-line distance?
The direct path is about 152.9 miles (246.1 km), while the road route adds roughly 27.7 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM MST. If you want a more comfortable same-day return, try to leave by 12:58 PM MST.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $31.54 one way or $63.08 round trip. Estimated CO2 is about 56.6 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around Nogales and Partly Sunny near Mesa.
Stop Ideas Near Marana
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Marana.
Tucson
Benson
Maricopa
Flight Path Map
This map shows the direct air route between Nogales and Mesa. Straight-line distance: 152.9 mi (246.07 km).
#1 Nogales
City in and county seat of Santa Cruz County, Arizona, United States, on the Mexican border
| Population | 20,107 |
| Coordinates | 31.3403800, -110.9342500 |
| Altitude | 1168 |
| Country | United States |
#2 Mesa
The fourth most populous city in Arizona and the center of the Mesa metropolitan area.
| Population | 528,159 |
| Coordinates | 33.4222700, -111.8226400 |
| Altitude | 378 |
| Country | United States |
End: East University Drive (-111.82264, 33.422353)
Estimated Travel Time
Distance: 291 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 06h 00m |
| 40 mph (64.37 km/h) | 04h 30m |
| 50 mph (80.47 km/h) | 03h 36m |
| 60 mph (96.56 km/h) | 03h 00m |
| 70 mph (112.65 km/h) | 02h 34m |
| 80 mph (129 km/h) | 02h 15m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.95 | $31.54 | $63.08 |
| Mid-grade | $5.34 | $34.00 | $68.01 |
| Premium | $5.57 | $35.46 | $70.91 |
| Diesel | $6.37 | $40.55 | $81.10 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Arizona · Apr 16, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.