How far is New Madrid, MO from Saint Joseph, MO?
The driving distance from New Madrid, MO to Saint Joseph, MO is about 455.5 miles (733.1 km), with a travel time of about 07h 02m by car.
- The straight-line flight distance is about 362.9 miles (584.1 km).
- For a round trip, plan for roughly 14h 04m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 07h 02m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Missouri, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Showers And Thunderstorms Likely
Showers And Thunderstorms Likely
Driving Route Map
The map below follows the saved road route between New Madrid and Saint Joseph.
Turn-by-Turn Driving Directions
Step-by-step road directions between New Madrid and Saint Joseph.
-
1
Start on the route
28 m · 9 sec
-
2
Turn right onto Mill Street
1508 ft · 43 sec · Mill Street
-
3
Turn right onto Kings Highway
1.3 km · 2 min · Kings Highway
-
4
Turn left onto Dawson Road
716 ft · 20 sec · Dawson Road
-
5
Turn right
2.6 mi · 4 min
-
6
Take the ramp right toward I 55 North: Sikeston
1267 ft · 31 sec
-
7
Merge slight left
43.7 mi · 47 min
-
8
Keep slight left
101.5 mi · 1 hr 49 min
-
9
Continue on Rosa Parks Highway
1.3 mi · 2 min · Rosa Parks Highway
-
10
Take the exit slight right toward I 270 West, I 255 East: Kansas City, Chicago
1279 ft · 27 sec
-
11
Keep slight left to continue on I 270 West: Kansas City
118 m · 8 sec
-
12
Continue on I 270 West
1.2 km · 1 min
-
13
Merge slight left
11.5 mi · 14 min
-
14
Take the exit slight right toward I 64, US 40, US 61: Wentzville, Saint Louis
705 ft · 17 sec
-
15
Keep slight left to continue on I 64 West, US 40 West, US 61 North: Wentzville
2009 ft · 49 sec
-
16
Continue on I 64 West, US 40 West, US 61 North: Wentzville
674 ft · 10 sec
-
17
Merge slight left onto Avenue of the Saints
25.4 mi · 31 min · Avenue of the Saints
-
18
Take the exit slight left toward I 70 West, US 40 West: Kansas City
3047 ft · 1 min
-
19
Merge slight left onto Dwight D Eisenhower Highway
80.7 mi · 1 hr 35 min · Dwight D Eisenhower Highway
-
20
Continue on Sheriff Roger I. Wilson Memorial Highway
2 mi · 2 min · Sheriff Roger I. Wilson Memorial Highway
-
21
Continue on Highway Patrol Sgt. Benjamin Booth Memorial Highway
1.6 mi · 2 min · Highway Patrol Sgt. Benjamin Booth Memorial Highway
-
22
Continue on Dwight D. Eisenhower Highway
1.8 mi · 2 min · Dwight D. Eisenhower Highway
-
23
Continue on U.S. Submarine Veterans' Memorial Highway
54.4 mi · 58 min · U.S. Submarine Veterans' Memorial Highway
-
24
Continue on Dwight D. Eisenhower Highway
52.5 mi · 57 min · Dwight D. Eisenhower Highway
-
25
Continue on Truman/Eisenhower Presidential Highway
2.7 mi · 3 min · Truman/Eisenhower Presidential Highway
-
26
Continue on Clifton J. Scott Memorial Highway
1.8 mi · 2 min · Clifton J. Scott Memorial Highway
-
27
Continue on Truman/Eisenhower Presidential Highway
2.9 mi · 3 min · Truman/Eisenhower Presidential Highway
-
28
Continue on George Brett Super Highway
1.4 km · 58 sec · George Brett Super Highway
-
29
Take the exit slight right toward I 435 North, US 24 East: Des Moines
1.1 mi · 2 min
-
30
Merge slight left onto Lamar Hunt Memorial Highway
7.8 mi · 9 min · Lamar Hunt Memorial Highway
-
31
Continue on I435 N
1.3 mi · 1 min · I435 N
-
32
Continue straight
20.9 mi · 22 min
-
33
Keep slight left to continue on I 29 North, US 71 North: Saint Joseph
26 mi · 28 min
-
34
Take the exit slight right toward I 229 North: Downtown Saint Joseph
2673 ft · 54 sec
-
35
Continue straight
5.7 mi · 7 min
-
36
Take the exit slight right toward Central Business District
1382 ft · 34 sec
-
37
Continue on Edmond Street
2408 ft · 58 sec · Edmond Street
-
38
Turn left onto South 10th Street
841 ft · 21 sec · South 10th Street
-
39
Turn right onto Frederick Avenue
116 m · 6 sec · Frederick Avenue
-
40
Turn slight right onto Walter Welsh Avenue
42 m · 3 sec · Walter Welsh Avenue
-
41
Arrive at your destination
0 m · 1 sec · Walter Welsh Avenue
Car Route Details
A richer read on the saved driving route between New Madrid and Saint Joseph.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
I 55 North
Keep slight left
102 mi · 01h 49m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Showers And Thunderstorms Likely leaving New Madrid and Showers And Thunderstorms Likely near Saint Joseph.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from New Madrid to Saint Joseph?
The road trip is about 455.5 miles (733.1 km) and usually takes 07h 02m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
New Florence is a useful midpoint, sitting about 227.5 miles from New Madrid and 228.1 miles from Saint Joseph.
How much longer is the road route than the straight-line distance?
The direct path is about 362.9 miles (584.1 km), while the road route adds roughly 92.6 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM CDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $60.60 one way or $121.20 round trip. Estimated CO2 is about 142.8 kg one way.
What should you check before leaving?
Before you leave, expect Showers And Thunderstorms Likely around New Madrid and Showers And Thunderstorms Likely near Saint Joseph.
Stop Ideas Near New Florence
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to New Florence.
Hermann
Washington
Jefferson City
Kirkwood
Flight Path Map
This map shows the direct air route between New Madrid and Saint Joseph. Straight-line distance: 362.92 mi (584.06 km).
#1 New Madrid
City in Missouri, United States
| Population | 2,765 |
| Coordinates | 36.5864500, -89.5278500 |
| Altitude | 90 |
| Country | United States |
#2 Saint Joseph
The most populous city in Buchanan County, Missouri.
| Population | 74,074 |
| Coordinates | 39.7686100, -94.8466300 |
| Altitude | 270 |
| Country | United States |
End: Walter Welsh Avenue (-94.846632, 39.768853)
Estimated Travel Time
Distance: 733 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 15h 10m |
| 40 mph (64.37 km/h) | 11h 23m |
| 50 mph (80.47 km/h) | 09h 06m |
| 60 mph (96.56 km/h) | 07h 35m |
| 70 mph (112.65 km/h) | 06h 30m |
| 80 mph (129 km/h) | 05h 40m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $60.60 | $121.20 |
| Mid-grade | $4.25 | $68.35 | $136.69 |
| Premium | $4.65 | $74.79 | $149.58 |
| Diesel | $5.30 | $85.24 | $170.47 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Apr 19, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.