How far is Murphysboro, IL from Cicero, IL?
The driving distance from Murphysboro, IL to Cicero, IL is about 339.2 miles (545.9 km), with a travel time of about 05h 25m by car.
- The straight-line flight distance is about 294.2 miles (473.4 km).
- For a round trip, plan for roughly 10h 51m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 25m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Village in Coles County, Illinois, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Mostly Cloudy then Rain Likely
Driving Route Map
The map below follows the saved road route between Murphysboro and Cicero.
Turn-by-Turn Driving Directions
Step-by-step road directions between Murphysboro and Cicero.
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1
Start on North 11th Street
20 m · 8 sec · North 11th Street
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2
Turn left onto Walnut Street
2741 ft · 1 min · Walnut Street
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3
Turn left onto North 2nd Street
1.5 km · 1 min · North 2nd Street
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4
Turn right
11.3 mi · 16 min
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5
Turn right onto Cambria Road
1.5 mi · 2 min · Cambria Road
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6
Enter the roundabout and take exit 3 toward Herrin Road
67 m · 4 sec · Herrin Road
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7
Exit the roundabout onto Herrin Road
3.5 mi · 5 min · Herrin Road
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8
Continue on West Herrin Street
3.1 mi · 5 min · West Herrin Street
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9
Continue on Herrin Road
3.3 mi · 5 min · Herrin Road
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10
Take the ramp left
1275 ft · 31 sec
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11
Merge slight left onto Ken Gray Expressway
36.7 mi · 40 min · Ken Gray Expressway
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12
Keep slight right to continue on Ken Gray Expressway
67.5 mi · 1 hr 13 min · Ken Gray Expressway
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13
Keep slight left to continue on I 57 North: Chicago
178.5 mi · 3 hr 12 min
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14
Take the exit slight right toward Vollmer Road
1475 ft · 42 sec
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15
Keep slight left to continue on Vollmer Road West
159 m · 17 sec
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16
Turn right onto Vollmer Road
1892 ft · 40 sec · Vollmer Road
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17
Turn left onto Cicero Avenue
10.8 mi · 17 min · Cicero Avenue
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18
Continue on South Cicero Avenue
10.6 mi · 17 min · South Cicero Avenue
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19
Turn left onto West 31st Street
2705 ft · 58 sec · West 31st Street
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20
Turn right onto South Laramie Avenue
1 km · 1 min · South Laramie Avenue
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21
Arrive at your destination
0 m · 1 sec · South Laramie Avenue
Car Route Details
A richer read on the saved driving route between Murphysboro and Cicero.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
I 57 North
Keep slight left to continue on I 57 North: Chicago
179 mi · 03h 12m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Sunny leaving Murphysboro and Mostly Cloudy then Rain Likely near Cicero.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Murphysboro to Cicero?
The road trip is about 339.2 miles (545.9 km) and usually takes 05h 25m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Humboldt is a useful midpoint, sitting about 165.3 miles from Murphysboro and 173.9 miles from Cicero.
How much longer is the road route than the straight-line distance?
The direct path is about 294.2 miles (473.4 km), while the road route adds roughly 45 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 6:08 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $45.14 one way or $90.28 round trip. Estimated CO2 is about 106.4 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Murphysboro and Mostly Cloudy then Rain Likely near Cicero.
Stop Ideas Near Humboldt
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Humboldt.
Mattoon station
Effingham
Illinois Terminal
Rantoul
Flight Path Map
This map shows the direct air route between Murphysboro and Cicero. Straight-line distance: 294.18 mi (473.44 km).
#1 Murphysboro
Town in Illinois
| Population | 7,384 |
| Coordinates | 37.7645000, -89.3350900 |
| Altitude | 128 |
| Country | United States |
#2 Cicero
Town in Illinois
| Population | 79,727 |
| Coordinates | 41.8455900, -87.7539400 |
| Altitude | 184 |
| Country | United States |
End: South Laramie Avenue (-87.753926, 41.84559)
Estimated Travel Time
Distance: 546 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 11h 18m |
| 40 mph (64.37 km/h) | 08h 28m |
| 50 mph (80.47 km/h) | 06h 47m |
| 60 mph (96.56 km/h) | 05h 39m |
| 70 mph (112.65 km/h) | 04h 50m |
| 80 mph (129 km/h) | 04h 13m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $45.14 | $90.28 |
| Mid-grade | $4.25 | $50.91 | $101.82 |
| Premium | $4.65 | $55.71 | $111.42 |
| Diesel | $5.30 | $63.49 | $126.98 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Illinois · May 13, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.