How far is Mission, TX from San Antonio, TX?
The driving distance from Mission, TX to San Antonio, TX is about 245.8 miles (395.5 km), with a travel time of about 03h 38m by car.
- The straight-line flight distance is about 221.9 miles (357.1 km).
- For a round trip, plan for roughly 07h 17m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 38m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Chance Showers And Thunderstorms then Slight Chance Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Mission and San Antonio.
Turn-by-Turn Driving Directions
Step-by-step road directions between Mission and San Antonio.
-
1
Start on East Tom Landry Street
41 m · 10 sec · East Tom Landry Street
-
2
Turn left onto North Conway Avenue
1.1 mi · 2 min · North Conway Avenue
-
3
Turn left onto US 83 Exwy Service Road
47 m · 3 sec · US 83 Exwy Service Road
-
4
Continue on East Expressway 83
3058 ft · 1 min · East Expressway 83
-
5
Take the ramp straight toward I 2 East, US 83 East
1919 ft · 47 sec
-
6
Merge slight left
8 mi · 9 min
-
7
Take the exit slight right toward I 69C North, US 281: Edinburg
1.6 km · 2 min
-
8
Continue straight
21.8 mi · 23 min
-
9
Continue straight
57.1 mi · 1 hr
-
10
Keep slight right
70.2 mi · 1 hr 20 min
-
11
Keep slight left to continue on Nueces Street
14.7 mi · 19 min · Nueces Street
-
12
Continue straight
1199 ft · 16 sec
-
13
Take the exit straight
68.8 mi · 1 hr 11 min
-
14
Take the exit slight right toward Commerce Street, Downtown, The Alamo
1358 ft · 33 sec
-
15
Turn straight onto Interstate 37 South
116 m · 12 sec · Interstate 37 South
-
16
Turn left onto East Commerce Street
1.4 km · 2 min · East Commerce Street
-
17
Turn left onto Military Plaza
119 m · 16 sec · Military Plaza
-
18
Turn left onto Dolorosa Street
100 m · 8 sec · Dolorosa Street
-
19
Arrive at your destination
0 m · 1 sec · Dolorosa Street
Car Route Details
A richer read on the saved driving route between Mission and San Antonio.
Interchange-aware route
The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.
I 69C North
Keep slight right
70.2 mi · 01h 20m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Mostly Sunny leaving Mission and Chance Showers And Thunderstorms then Slight Chance Showers And Thunderstorms near San Antonio.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Mission to San Antonio?
The road trip is about 245.8 miles (395.5 km) and usually takes 03h 38m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Alice is a useful midpoint, sitting about 122.9 miles from Mission and 122.8 miles from San Antonio.
How much longer is the road route than the straight-line distance?
The direct path is about 221.9 miles (357.1 km), while the road route adds roughly 23.9 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 9:42 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $32.76 one way or $65.53 round trip. Estimated CO2 is about 77.1 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around Mission and Chance Showers And Thunderstorms then Slight Chance Showers And Thunderstorms near San Antonio.
Flight Path Map
This map shows the direct air route between Mission and San Antonio. Straight-line distance: 221.9 mi (357.12 km).
#1 Mission
A city in Hidalgo County, Texas.
| Population | 84,496 |
| Coordinates | 26.2159100, -98.3252900 |
| Altitude | 43 |
| Country | United States |
#2 San Antonio
The seventh most populous city in the United States and the center of the San Antonio metropolitan area.
| Population | 1,567,118 |
| Coordinates | 29.4241200, -98.4936300 |
| Altitude | 198 |
| Country | United States |
End: Dolorosa Street (-98.493645, 29.424163)
Estimated Travel Time
Distance: 395 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 08h 11m |
| 40 mph (64.37 km/h) | 06h 08m |
| 50 mph (80.47 km/h) | 04h 54m |
| 60 mph (96.56 km/h) | 04h 05m |
| 70 mph (112.65 km/h) | 03h 30m |
| 80 mph (129 km/h) | 03h 03m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.78 | $32.76 | $65.53 |
| Mid-grade | $4.25 | $36.86 | $73.73 |
| Premium | $4.59 | $39.80 | $79.61 |
| Diesel | $3.99 | $34.62 | $69.24 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Texas · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.