How far is Middlesex, NY from Buffalo, NY?
The driving distance from Middlesex, NY to Buffalo, NY is about 105.3 miles (169.4 km), with a travel time of about 01h 54m by car.
- The straight-line flight distance is about 82.4 miles (132.6 km).
- For a round trip, plan for roughly 03h 49m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM EDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 01h 54m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Monroe County, New York, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Partly Sunny
Slight Chance Rain Showers then Mostly Sunny
Driving Route Map
The map below follows the saved road route between Middlesex and Buffalo.
Turn-by-Turn Driving Directions
Step-by-step road directions between Middlesex and Buffalo.
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1
Start on Water Street
2181 ft · 38 sec · Water Street
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2
At the end of the road, turn right onto State Route 364
12.1 mi · 18 min · State Route 364
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3
Continue on Eastern Boulevard
1.3 mi · 3 min · Eastern Boulevard
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4
Keep slight right to continue on South Main Street
2.1 mi · 3 min · South Main Street
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5
Continue on Rochester Road
7.2 mi · 9 min · Rochester Road
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6
Keep slight left to continue on I 90 West: Buffalo
2836 ft · 39 sec
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7
Merge slight left onto New York State Thruway
73.7 mi · 1 hr 26 min · New York State Thruway
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8
Take the exit slight right toward NY 33 West: Buffalo
1901 ft · 46 sec
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9
Merge slight left onto Kensington Expressway
6.4 mi · 9 min · Kensington Expressway
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10
Keep slight left to continue on Oak Street
2170 ft · 40 sec
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11
Continue on Oak Street
131 m · 14 sec · Oak Street
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12
Turn right onto Genesee Street
1172 ft · 39 sec · Genesee Street
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13
Turn right onto East Huron Street
729 ft · 34 sec · East Huron Street
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14
Turn left onto Franklin Street
716 ft · 23 sec · Franklin Street
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15
Turn right onto Genesee Street
123 m · 12 sec · Genesee Street
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16
Enter the roundabout toward Niagara Square
119 m · 12 sec · Niagara Square
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17
Arrive at your destination
0 m · 1 sec · Niagara Square
Car Route Details
A richer read on the saved driving route between Middlesex and Buffalo.
Straightforward drive
The saved road route has a manageable number of maneuvers and should be easy to follow with normal attention to signs.
New York State Thruway
Merge slight left onto New York State Thruway
73.7 mi · 01h 26m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Partly Sunny leaving Middlesex and Slight Chance Rain Showers then Mostly Sunny near Buffalo.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Middlesex to Buffalo?
The road trip is about 105.3 miles (169.4 km) and usually takes 01h 54m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Riga is a useful midpoint, sitting about 52.5 miles from Middlesex and 52.8 miles from Buffalo.
How much longer is the road route than the straight-line distance?
The direct path is about 82.4 miles (132.6 km), while the road route adds roughly 22.9 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM EDT. If you want a more comfortable same-day return, try to leave by 2:40 PM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $14.87 one way or $29.75 round trip. Estimated CO2 is about 33 kg one way.
What should you check before leaving?
Before you leave, expect Partly Sunny around Middlesex and Slight Chance Rain Showers then Mostly Sunny near Buffalo.
Stop Ideas Near Riga
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Riga.
Louise M. Slaughter Rochester Station
Buffalo–Depew station
Buffalo–Exchange Street
Niagara Falls Station and Customhouse Interpretive Center
Flight Path Map
This map shows the direct air route between Middlesex and Buffalo. Straight-line distance: 82.42 mi (132.64 km).
#1 Middlesex
City in Yates County, New York, United States of America
| Population | 1,453 |
| Coordinates | 42.7047900, -77.2716500 |
| Altitude | 235 |
| Country | United States |
#2 Buffalo
The second most populous city in New York.
| Population | 254,479 |
| Coordinates | 42.8864500, -78.8783700 |
| Altitude | 183 |
| Country | United States |
End: Niagara Square (-78.878786, 42.886515)
Estimated Travel Time
Distance: 169 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 03h 30m |
| 40 mph (64.37 km/h) | 02h 37m |
| 50 mph (80.47 km/h) | 02h 06m |
| 60 mph (96.56 km/h) | 01h 45m |
| 70 mph (112.65 km/h) | 01h 30m |
| 80 mph (129 km/h) | 01h 18m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.01 | $14.87 | $29.75 |
| Mid-grade | $4.48 | $16.62 | $33.25 |
| Premium | $4.86 | $18.03 | $36.07 |
| Diesel | $4.69 | $17.41 | $34.83 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in New York · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.