How far is Melissa, TX from San Antonio, TX?
The driving distance from Melissa, TX to San Antonio, TX is about 336.2 miles (541 km), with a travel time of about 04h 55m by car.
- The straight-line flight distance is about 289.9 miles (466.5 km).
- For a round trip, plan for roughly 09h 51m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 55m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Bell County, Texas
Route Weather Snapshot
Check the forecast at both ends before you head out.
Slight Chance Showers And Thunderstorms
Chance Showers And Thunderstorms then Slight Chance Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Melissa and San Antonio.
Turn-by-Turn Driving Directions
Step-by-step road directions between Melissa and San Antonio.
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1
Start on West Cooper Street
114 m · 22 sec · West Cooper Street
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2
At the end of the road, turn left onto McKinney Street
1 mi · 2 min · McKinney Street
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3
Turn right onto Sam Rayburn Highway
1.6 km · 1 min · Sam Rayburn Highway
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4
Keep slight left to continue on US 75 South, TX 121 South
1.3 km · 2 min
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5
Merge slight left onto Central Expressway
35 mi · 38 min · Central Expressway
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6
Take the exit slight left toward Downtown, Good-Latimer Expressway
153 m · 12 sec
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7
Continue on North Central Expressway
1.2 km · 1 min · North Central Expressway
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8
Turn right onto Elm Street
93 m · 10 sec · Elm Street
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9
Turn left onto North Pearl Expressway
1086 ft · 29 sec · North Pearl Expressway
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10
Turn right onto Young Street
572 ft · 20 sec · Young Street
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11
Turn left onto South Harwood Street
96 m · 8 sec · South Harwood Street
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12
Turn right onto Canton Street
2105 ft · 48 sec · Canton Street
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13
Take the ramp slight left toward I 30 West
1773 ft · 38 sec
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14
Keep slight left to continue on I 35E South, I 35E North: Waco, Denton
607 ft · 15 sec
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15
Keep slight left to continue on I 35E North, I 35E South: Denton, Waco
67 m · 5 sec
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16
Keep slight left to continue on I 35E South: Waco
1915 ft · 30 sec
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17
Continue on South R L Thornton Freeway
2866 ft · 44 sec · South R L Thornton Freeway
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18
Continue on South R L Thornton Freeway
89.3 mi · 1 hr 32 min · South R L Thornton Freeway
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19
Continue on North Jack Kultgen Expressway
6.6 mi · 8 min · North Jack Kultgen Expressway
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20
Continue on Purple Heart Trail
37.9 mi · 39 min · Purple Heart Trail
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21
Keep slight left
55.8 mi · 59 min
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22
Keep slight left to continue on Purple Heart Trail
49.8 mi · 55 min · Purple Heart Trail
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23
Continue on Interstate Highway 35
1.7 mi · 2 min · Interstate Highway 35
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24
Continue on Purple Heart Trail
11.9 mi · 13 min · Purple Heart Trail
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25
Continue on North Pan Am Expressway
10 mi · 12 min · North Pan Am Expressway
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26
Keep slight left to continue on North Pan Am Expressway
6.4 mi · 8 min · North Pan Am Expressway
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27
Keep slight left to continue on North Pan Am Expressway
2907 ft · 41 sec · North Pan Am Expressway
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28
Take the exit slight right toward Lexington Avenue, Main Avenue, San Pedro Avenue
684 ft · 17 sec
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29
Turn straight onto East Elmira Street
526 ft · 17 sec · East Elmira Street
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30
Turn left onto North Main Avenue
830 ft · 19 sec · North Main Avenue
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31
Enter the roundabout and take exit 2 toward Navarro Street
49 m · 3 sec · Navarro Street
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32
Exit the roundabout onto Navarro Street
34 m · 2 sec · Navarro Street
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33
Keep slight right to continue on North Main Avenue
2181 ft · 52 sec · North Main Avenue
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34
Turn right onto West Travis Street
68 m · 11 sec · West Travis Street
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35
Turn left onto North Flores Street
807 ft · 20 sec · North Flores Street
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36
Continue on Military Plaza
119 m · 16 sec · Military Plaza
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37
Turn left onto Dolorosa Street
100 m · 8 sec · Dolorosa Street
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38
Arrive at your destination
0 m · 1 sec · Dolorosa Street
Car Route Details
A richer read on the saved driving route between Melissa and San Antonio.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
South R L Thornton Freeway
Continue on South R L Thornton Freeway
89.3 mi · 01h 32m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Slight Chance Showers And Thunderstorms leaving Melissa and Chance Showers And Thunderstorms then Slight Chance Showers And Thunderstorms near San Antonio.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Melissa to San Antonio?
The road trip is about 336.2 miles (541 km) and usually takes 04h 55m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Troy is a useful midpoint, sitting about 156.3 miles from Melissa and 179.8 miles from San Antonio.
How much longer is the road route than the straight-line distance?
The direct path is about 289.9 miles (466.5 km), while the road route adds roughly 46.3 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 7:08 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $44.82 one way or $89.64 round trip. Estimated CO2 is about 105.4 kg one way.
What should you check before leaving?
Before you leave, expect Slight Chance Showers And Thunderstorms around Melissa and Chance Showers And Thunderstorms then Slight Chance Showers And Thunderstorms near San Antonio.
Stop Ideas Near Troy
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Troy.
Temple
McGregor
Killeen, Texas
Waco, TX
Flight Path Map
This map shows the direct air route between Melissa and San Antonio. Straight-line distance: 289.88 mi (466.52 km).
#1 Melissa
City in Collin County, Texas, United States
| Population | 13,793 |
| Coordinates | 33.2859500, -96.5727700 |
| Altitude | 207 |
| Country | United States |
#2 San Antonio
The seventh most populous city in the United States and the center of the San Antonio metropolitan area.
| Population | 1,567,118 |
| Coordinates | 29.4241200, -98.4936300 |
| Altitude | 198 |
| Country | United States |
End: Dolorosa Street (-98.493645, 29.424163)
Estimated Travel Time
Distance: 541 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 11h 12m |
| 40 mph (64.37 km/h) | 08h 24m |
| 50 mph (80.47 km/h) | 06h 43m |
| 60 mph (96.56 km/h) | 05h 36m |
| 70 mph (112.65 km/h) | 04h 48m |
| 80 mph (129 km/h) | 04h 11m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.78 | $44.82 | $89.64 |
| Mid-grade | $4.25 | $50.43 | $100.86 |
| Premium | $4.59 | $54.45 | $108.90 |
| Diesel | $3.99 | $47.36 | $94.71 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Texas · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.