How far is Mayfield, PA from Pittsburgh, PA?
Fastest route
From Mayfield, Pennsylvania to Pittsburgh, Pennsylvania. The distance is approximately 296 miles (476.7 kilometers), and the estimated travel time is 4 hours and 51 minutes.
Directions
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🚗 Head southeast on Maple St toward Hill St, then turn right at the 1st cross street onto Hill St.
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🛣️ Turn right at the 2nd cross street onto Poplar St, continue onto Washington Ave.
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🛣️ Turn left onto PA-107 E/Rushbrook St, then right to merge onto US-6 W.
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🛣️ Follow I-81 S, I-80 W, and I-99 S to US-22 W in Allegheny Township. Take exit 28 from I-99 S.
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🚙 Use the left lane to merge onto I-81 S toward Wilkes-Barre. Take exit 151B to merge onto I-80 W toward Bloomsburg.
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🚙 Take exit 161 for US-220 S/PA-26 toward I-99 S/Bellefonte, and turn left onto PA-26 S/US-220 S.
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🛣️ Continue onto I-99 S/US-220 S, then take exit 28 for US-22 W toward Ebensburg.
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🚗 Get on I-376 W/US-22 W in Monroeville, and use the right lane to take the I-376 W/US-22 W ramp to Pittsburgh.
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🚗 Follow I-376 W/US-22 W to Grant St in Pittsburgh. Take exit 71A from I-376 W/US-22 W.
Tips & Suggestions
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⛽ Plan for refueling stops along the way, especially on longer stretches of highway.
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🚓 Obey traffic rules and speed limits to ensure a safe journey.
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🚧 Check real-time traffic conditions and consider using navigation apps to find the fastest route.
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🍴 Pack some snacks and drinks for the trip to stay energized and hydrated.
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🚗 Consider taking short breaks during the drive to stretch and relax.
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🛣️ Familiarize yourself with the route beforehand to avoid missing any exits.
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📱 Keep your phone charged and have emergency contacts handy in case of any issues.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 05m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Township in Centre County, Pennsylvania
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Driving Route Map
The map below follows the saved road route between Mayfield and Pittsburgh.
Turn-by-Turn Driving Directions
Step-by-step road directions between Mayfield and Pittsburgh.
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1
Start on Maple Street
33 m · 7 sec · Maple Street
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2
Turn right onto Hill Street
972 ft · 45 sec · Hill Street
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3
Turn right onto Poplar Street
1241 ft · 43 sec · Poplar Street
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4
Turn left onto Main Street
1337 ft · 27 sec · Main Street
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5
Continue on Washington Avenue
814 ft · 22 sec · Washington Avenue
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6
Turn left onto Rushbrook Street
1.2 km · 2 min · Rushbrook Street
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7
Take the ramp right toward US 6 West: Scranton
1907 ft · 48 sec
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8
Merge slight left onto Governor Robert P. Casey Highway
10 mi · 12 min · Governor Robert P. Casey Highway
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9
Keep slight left to continue on I 81 South: Wilkes-Barre
1.2 mi · 3 min
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10
Merge slight left onto American Legion Memorial Highway
35 mi · 42 min · American Legion Memorial Highway
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11
Take the exit slight right toward I-80 West: Bloomsburg
1.1 km · 1 min
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12
Merge slight left onto Keystone Shortway
98.5 mi · 1 hr 47 min · Keystone Shortway
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13
Take the exit slight right toward I 99 South, US 220 South, PA 26: Bellefonte
1410 ft · 54 sec
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14
Turn left onto Jacksonville Road
24.2 mi · 28 min · Jacksonville Road
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15
Keep slight left to continue on I 99 South, US 220 South: Port Matilda, Altoona
33.8 mi · 37 min
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16
Take the exit slight right toward US 22: Ebensburg, Hollidaysburg
1.3 km · 2 min
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17
Continue straight
2791 ft · 43 sec
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18
Continue on William Penn Highway
16.5 mi · 19 min · William Penn Highway
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19
Continue on Admiral Peary Highway
13.4 mi · 19 min · Admiral Peary Highway
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20
Continue on William Penn Highway
44.8 mi · 1 hr 6 min · William Penn Highway
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21
Keep slight right to continue on Penn-Lincoln Parkway East
13.5 mi · 18 min · Penn-Lincoln Parkway East
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22
Take the exit slight right toward Second Avenue
1137 ft · 39 sec
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23
Turn straight onto Second Avenue
1376 ft · 42 sec · Second Avenue
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24
At the end of the road, turn right onto Ross Street
978 ft · 32 sec · Ross Street
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25
Turn left onto Fifth Avenue
107 m · 10 sec · Fifth Avenue
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26
Turn right onto Grant Street
157 m · 22 sec · Grant Street
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27
Arrive at your destination
0 m · 1 sec · Grant Street
Car Route Details
A richer read on the saved driving route between Mayfield and Pittsburgh.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Keystone Shortway
Merge slight left onto Keystone Shortway
98.5 mi · 01h 47m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Mostly Sunny leaving Mayfield and Sunny near Pittsburgh.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Mayfield to Pittsburgh?
The road trip is about 296.1 miles (476.6 km) and usually takes 05h 05m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Curtin is a useful midpoint, sitting about 147.8 miles from Mayfield and 148.4 miles from Pittsburgh.
How much longer is the road route than the straight-line distance?
The direct path is about 244.6 miles (393.7 km), while the road route adds roughly 51.5 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 6:50 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $42.70 one way or $85.40 round trip. Estimated CO2 is about 92.9 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around Mayfield and Sunny near Pittsburgh.
Stop Ideas Near Curtin
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Curtin.
Lewistown
Tyrone
Huntingdon
Altoona Transportation Center
Flight Path Map
This map shows the direct air route between Mayfield and Pittsburgh. Straight-line distance: 244.62 mi (393.67 km).
#1 Mayfield
Borough in Lackawanna County, Pennsylvania
| Population | 1,685 |
| Coordinates | 41.5381400, -75.5360200 |
| Altitude | 291 |
| Country | United States |
#2 Pittsburgh
The second most populous city in Pennsylvania and the center of the Pittsburgh metropolitan area.
| Population | 299,226 |
| Coordinates | 40.4406200, -79.9958900 |
| Altitude | 233 |
| Country | United States |
End: Grant Street (-79.995923, 40.440633)
Estimated Travel Time
Distance: 477 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 09h 52m |
| 40 mph (64.37 km/h) | 07h 24m |
| 50 mph (80.47 km/h) | 05h 55m |
| 60 mph (96.56 km/h) | 04h 56m |
| 70 mph (112.65 km/h) | 04h 13m |
| 80 mph (129 km/h) | 03h 41m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.09 | $42.70 | $85.40 |
| Mid-grade | $4.60 | $48.06 | $96.12 |
| Premium | $4.95 | $51.77 | $103.54 |
| Diesel | $5.98 | $62.49 | $124.98 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Pennsylvania · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.