How far is Mason City, IA from Muscatine, IA?
The driving distance from Mason City, IA to Muscatine, IA is about 204.8 miles (329.6 km), with a travel time of about 04h 05m by car.
- The straight-line flight distance is about 162.6 miles (261.7 km).
- For a round trip, plan for roughly 08h 10m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 05m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Iowa
Route Weather Snapshot
Check the forecast at both ends before you head out.
Slight Chance Showers And Thunderstorms then Mostly Sunny
Chance Rain Showers then Slight Chance Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Mason City and Muscatine.
Turn-by-Turn Driving Directions
Step-by-step road directions between Mason City and Muscatine.
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1
Start on 2nd Street Northeast
7 m · 6 sec · 2nd Street Northeast
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2
Turn left onto North Federal Avenue
100 m · 20 sec · North Federal Avenue
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3
Turn left onto 1st Street Northeast
2567 ft · 57 sec · 1st Street Northeast
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4
At the end of the road, turn left onto East State Street
2988 ft · 60 sec · East State Street
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5
Turn slight right onto Maple Drive
2017 ft · 57 sec · Maple Drive
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6
Turn left onto 4th Street Southeast
2.7 mi · 4 min · 4th Street Southeast
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7
Turn right onto Thrush Avenue
2.6 mi · 4 min · Thrush Avenue
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8
Take the ramp left
2241 ft · 55 sec
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9
Merge slight left onto Avenue of the Saints
69.1 mi · 1 hr 20 min · Avenue of the Saints
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10
Take the exit slight right toward US 218 south: Waterloo
97 m · 8 sec
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11
Continue on US 218 south: Waterloo
1625 ft · 40 sec
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12
Merge slight left onto Leo P Rooff Expressway
6.7 mi · 8 min · Leo P Rooff Expressway
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13
Continue on Washington Street
2.4 mi · 4 min · Washington Street
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14
Keep slight right to continue on I-380 south, US 20, IA 27: Cedar Rapids, Dubuque, Cedar Falls
6.5 mi · 8 min
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15
Keep slight right to continue on Avenue of the Saints
64.7 mi · 1 hr 12 min · Avenue of the Saints
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16
Take the exit slight right toward I 80
1362 ft · 33 sec
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17
Keep slight left to continue on I 80 East: Davenport
1.2 mi · 3 min
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18
Merge slight left
31 mi · 34 min
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19
Take the exit slight right toward US 6 West, IA 38 South: Wilton, Muscatine
1254 ft · 31 sec
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20
Turn right onto Rose Avenue
2.6 mi · 4 min · Rose Avenue
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21
Continue on United States Highway 6
2583 ft · 44 sec · United States Highway 6
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22
Continue on Grand Army of the Republic Highway
1.6 mi · 2 min · Grand Army of the Republic Highway
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23
Continue on State Highway 38
9.5 mi · 15 min · State Highway 38
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24
Continue on East 2nd Street
1 km · 1 min · East 2nd Street
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25
Enter the roundabout and take exit 1 toward Mulberry Avenue
4 m · 1 sec · Mulberry Avenue
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26
Exit the roundabout onto Mulberry Avenue
108 m · 16 sec · Mulberry Avenue
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27
Turn left onto East 3rd Street
110 m · 18 sec · East 3rd Street
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28
Turn right onto Walnut Street
48 m · 5 sec · Walnut Street
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29
Arrive at your destination
0 m · 1 sec · Walnut Street
Car Route Details
A richer read on the saved driving route between Mason City and Muscatine.
Interchange-aware route
The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.
Avenue of the Saints
Merge slight left onto Avenue of the Saints
69.1 mi · 01h 20m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Slight Chance Showers And Thunderstorms then Mostly Sunny leaving Mason City and Chance Rain Showers then Slight Chance Showers And Thunderstorms near Muscatine.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Mason City to Muscatine?
The road trip is about 204.8 miles (329.6 km) and usually takes 04h 05m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Brandon is a useful midpoint, sitting about 102.3 miles from Mason City and 102.5 miles from Muscatine.
How much longer is the road route than the straight-line distance?
The direct path is about 162.6 miles (261.7 km), while the road route adds roughly 42.2 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 8:50 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $27.26 one way or $54.53 round trip. Estimated CO2 is about 64.3 kg one way.
What should you check before leaving?
Before you leave, expect Slight Chance Showers And Thunderstorms then Mostly Sunny around Mason City and Chance Rain Showers then Slight Chance Showers And Thunderstorms near Muscatine.
Flight Path Map
This map shows the direct air route between Mason City and Muscatine. Straight-line distance: 162.58 mi (261.65 km).
#1 Mason City
City in Cerro Gordo County, Iowa
| Population | 26,931 |
| Coordinates | 43.1535700, -93.2010400 |
| Altitude | 344 |
| Country | United States |
#2 Muscatine
City in and county seat of Muscatine County, Iowa
| Population | 23,523 |
| Coordinates | 41.4244700, -91.0432100 |
| Altitude | 177 |
| Country | United States |
End: Muscatine (-91.04321, 41.42447)
Estimated Travel Time
Distance: 330 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 06h 49m |
| 40 mph (64.37 km/h) | 05h 07m |
| 50 mph (80.47 km/h) | 04h 05m |
| 60 mph (96.56 km/h) | 03h 24m |
| 70 mph (112.65 km/h) | 02h 55m |
| 80 mph (129 km/h) | 02h 33m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $27.26 | $54.53 |
| Mid-grade | $4.25 | $30.75 | $61.50 |
| Premium | $4.65 | $33.65 | $67.30 |
| Diesel | $5.30 | $38.35 | $76.70 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Iowa · May 13, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.