How far is Maryville, MO from St. Louis, MO?
The driving distance from Maryville, MO to St. Louis, MO is about 346.5 miles (557.7 km), with a travel time of about 05h 23m by car.
- The straight-line flight distance is about 276.1 miles (444.3 km).
- For a round trip, plan for roughly 10h 46m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 23m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Pettis County, Missouri, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Rain Showers
Showers And Thunderstorms Likely
Driving Route Map
The map below follows the saved road route between Maryville and St. Louis.
Turn-by-Turn Driving Directions
Step-by-step road directions between Maryville and St. Louis.
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1
Start on East 1st Street
41 m · 10 sec · East 1st Street
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2
Turn left onto South Main Street
2.2 mi · 4 min · South Main Street
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3
Continue on US 71 (MO)
30 mi · 34 min · US 71 (MO)
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4
Take the exit slight left toward I 29 South, US 71 South, US 59 South: Kansas City
3.2 mi · 4 min
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5
Continue straight
37.1 mi · 40 min
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6
Merge slight right
2.2 mi · 2 min
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7
Keep slight right to continue on I 435 East: Saint Louis
28 mi · 31 min
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8
Keep slight right to continue on I 70, US 24 West, US 40: Saint Louis, Kansas City, Sports Complex
1500 ft · 23 sec
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9
Keep slight left to continue on I 70 East: Saint Louis
1.2 mi · 2 min
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10
Keep slight left to continue on I 70 East: Saint Louis
143 m · 12 sec
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11
Merge slight left onto George Brett Super Highway
2213 ft · 29 sec · George Brett Super Highway
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12
Continue on Truman/Eisenhower Presidential Highway
2.9 mi · 3 min · Truman/Eisenhower Presidential Highway
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13
Continue on Clifton J. Scott Memorial Highway
1.8 mi · 2 min · Clifton J. Scott Memorial Highway
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14
Continue on Truman/Eisenhower Presidential Highway
2.6 mi · 3 min · Truman/Eisenhower Presidential Highway
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15
Continue on Dwight D. Eisenhower Highway
52.5 mi · 57 min · Dwight D. Eisenhower Highway
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16
Continue on U.S. Submarine Veterans' Memorial Highway
32 mi · 34 min · U.S. Submarine Veterans' Memorial Highway
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17
Keep slight left to continue on U.S. Submarine Veterans' Memorial Highway
22.4 mi · 24 min · U.S. Submarine Veterans' Memorial Highway
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18
Continue on Dwight D. Eisenhower Highway
1.8 mi · 2 min · Dwight D. Eisenhower Highway
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19
Continue on Highway Patrol Sgt. Benjamin Booth Memorial Highway
1.6 mi · 2 min · Highway Patrol Sgt. Benjamin Booth Memorial Highway
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20
Continue on Sheriff Roger I. Wilson Memorial Highway
1.9 mi · 2 min · Sheriff Roger I. Wilson Memorial Highway
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21
Continue on Dwight D. Eisenhower Highway
81 mi · 1 hr 35 min · Dwight D. Eisenhower Highway
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22
Take the exit slight right toward I 64 East, US 40 East, US 61 South: Chesterfield
1567 ft · 33 sec
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23
Merge slight left onto Avenue of the Saints
27.7 mi · 34 min · Avenue of the Saints
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24
Continue on Daniel Boone Expressway
5.7 mi · 7 min · Daniel Boone Expressway
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25
Continue on Jack Buck Memorial Highway
5.8 mi · 7 min · Jack Buck Memorial Highway
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26
Take the exit slight right toward 14th Street
1115 ft · 34 sec
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27
Turn left onto South 14th Street
1715 ft · 42 sec · South 14th Street
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28
Turn right onto Market Street
956 ft · 25 sec · Market Street
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29
Arrive at your destination
0 m · 1 sec · Market Street
Car Route Details
A richer read on the saved driving route between Maryville and St. Louis.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Dwight D. Eisenhower Highway
Continue on Dwight D. Eisenhower Highway
81 mi · 01h 35m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Chance Rain Showers leaving Maryville and Showers And Thunderstorms Likely near St. Louis.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Maryville to St. Louis?
The road trip is about 346.5 miles (557.7 km) and usually takes 05h 23m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Houstonia is a useful midpoint, sitting about 172.6 miles from Maryville and 174 miles from St. Louis.
How much longer is the road route than the straight-line distance?
The direct path is about 276.1 miles (444.3 km), while the road route adds roughly 70.4 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 6:14 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $46.12 one way or $92.24 round trip. Estimated CO2 is about 108.7 kg one way.
What should you check before leaving?
Before you leave, expect Chance Rain Showers around Maryville and Showers And Thunderstorms Likely near St. Louis.
Stop Ideas Near Houstonia
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Houstonia.
Sedalia
Warrensburg
Lee's Summit
Independence
Flight Path Map
This map shows the direct air route between Maryville and St. Louis. Straight-line distance: 276.06 mi (444.28 km).
#1 Maryville
City in Nodaway County, Missouri, United States
| Population | 11,530 |
| Coordinates | 40.3461000, -94.8724700 |
| Altitude | 351 |
| Country | United States |
#2 St. Louis
The second most populous city in Missouri and the center of the St.
| Population | 315,685 |
| Coordinates | 38.6272700, -90.1978900 |
| Altitude | 142 |
| Country | United States |
End: Market Street (-90.197859, 38.627348)
Estimated Travel Time
Distance: 558 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 11h 32m |
| 40 mph (64.37 km/h) | 08h 39m |
| 50 mph (80.47 km/h) | 06h 55m |
| 60 mph (96.56 km/h) | 05h 46m |
| 70 mph (112.65 km/h) | 04h 57m |
| 80 mph (129 km/h) | 04h 19m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $46.12 | $92.24 |
| Mid-grade | $4.25 | $52.01 | $104.03 |
| Premium | $4.65 | $56.92 | $113.84 |
| Diesel | $5.30 | $64.87 | $129.74 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Apr 19, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.