How far is Markham, IL from Murphysboro, IL?
The driving distance from Markham, IL to Murphysboro, IL is about 313.3 miles (504.2 km), with a travel time of about 05h 50m by car.
- The straight-line flight distance is about 278.6 miles (448.3 km).
- For a round trip, plan for roughly 11h 41m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 50m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Illinois
Route Weather Snapshot
Check the forecast at both ends before you head out.
Showers And Thunderstorms Likely
Driving Route Map
The map below follows the saved road route between Markham and Murphysboro.
Turn-by-Turn Driving Directions
Step-by-step road directions between Markham and Murphysboro.
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1
Start on 163rd Street
20 m · 7 sec · 163rd Street
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2
Turn right onto Kedzie Avenue
2913 ft · 1 min · Kedzie Avenue
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3
Take the ramp slight right toward I 80 West
2482 ft · 1 min
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4
Merge slight left
2.3 mi · 3 min
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5
Take the exit slight left toward I 57 South: Memphis
1640 ft · 32 sec
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6
Merge slight right
187.1 mi · 3 hr 22 min
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7
Keep slight left to continue on I 57 South: Memphis
65.7 mi · 1 hr 11 min
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8
Keep slight right to continue on Ken Gray Expressway
32.7 mi · 35 min · Ken Gray Expressway
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9
Take the exit slight right toward Johnston City, Herrin
1506 ft · 39 sec
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10
Turn right onto Herrin Road
3.1 mi · 5 min · Herrin Road
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11
Continue on East Herrin Street
3.1 mi · 5 min · East Herrin Street
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12
Continue on Herrin Road
3.5 mi · 5 min · Herrin Road
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13
Enter the roundabout and take exit 1 toward Cambria Road
11 m · 1 sec · Cambria Road
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14
Exit the roundabout onto Cambria Road
1.5 mi · 2 min · Cambria Road
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15
Turn left onto Russell Street
11.3 mi · 16 min · Russell Street
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16
Turn left onto North 2nd Street
1.4 km · 1 min · North 2nd Street
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17
Turn right onto Walnut Street
2911 ft · 1 min · Walnut Street
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18
Turn right onto North 11th Street
20 m · 3 sec · North 11th Street
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19
Arrive at your destination
0 m · 1 sec · North 11th Street
Car Route Details
A richer read on the saved driving route between Markham and Murphysboro.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
I 57 South
Merge slight right
187 mi · 03h 22m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Rain leaving Markham and Showers And Thunderstorms Likely near Murphysboro.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Markham to Murphysboro?
The road trip is about 313.3 miles (504.2 km) and usually takes 05h 50m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Mattoon is a useful midpoint, sitting about 156.7 miles from Markham and 156.6 miles from Murphysboro.
How much longer is the road route than the straight-line distance?
The direct path is about 278.6 miles (448.3 km), while the road route adds roughly 34.7 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 5:18 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $51.59 one way or $103.19 round trip. Estimated CO2 is about 98.3 kg one way.
What should you check before leaving?
Before you leave, expect Rain around Markham and Showers And Thunderstorms Likely near Murphysboro.
Stop Ideas Near Mattoon
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Mattoon.
Mattoon station
Effingham
Illinois Terminal
Rantoul
Flight Path Map
This map shows the direct air route between Markham and Murphysboro. Straight-line distance: 278.56 mi (448.3 km).
#1 Markham
A city located in Cook County, Illinois.
| Population | 13,400 |
| Coordinates | 41.5936500, -87.6947700 |
| Altitude | 189 |
| Country | United States |
#2 Murphysboro
Town in Illinois
| Population | 7,384 |
| Coordinates | 37.7645000, -89.3350900 |
| Altitude | 128 |
| Country | United States |
End: Murphysboro (-89.33509, 37.7645)
Estimated Travel Time
Distance: 504 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 10h 26m |
| 40 mph (64.37 km/h) | 07h 49m |
| 50 mph (80.47 km/h) | 06h 15m |
| 60 mph (96.56 km/h) | 05h 13m |
| 70 mph (112.65 km/h) | 04h 28m |
| 80 mph (129 km/h) | 03h 54m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.67 | $51.59 | $103.19 |
| Mid-grade | $5.29 | $58.53 | $117.06 |
| Premium | $5.84 | $64.56 | $129.11 |
| Diesel | $6.57 | $72.68 | $145.35 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Illinois · Oct 15, 2026