How far is Manteo, NC from Winston-Salem, NC?
The driving distance from Manteo, NC to Winston-Salem, NC is about 292.4 miles (470.6 km), with a travel time of about 04h 38m by car.
- The straight-line flight distance is about 255.7 miles (411.5 km).
- For a round trip, plan for roughly 09h 16m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 38m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in North Carolina, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Showers And Thunderstorms Likely
Mostly Sunny
Driving Route Map
The map below follows the saved road route between Manteo and Winston-Salem.
Turn-by-Turn Driving Directions
Step-by-step road directions between Manteo and Winston-Salem.
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1
Start on N US Highway 64
1.5 mi · 3 min · N US Highway 64
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2
Take the ramp slight right
55 m · 5 sec
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3
Merge slight left
18.4 mi · 25 min
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4
Keep slight left
67.3 mi · 1 hr 27 min
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5
Turn left
1.8 mi · 2 min
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6
Continue straight
56.5 mi · 1 hr 1 min
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7
Continue straight
27.8 mi · 30 min
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8
Take the exit slight right toward Rolesville Road
1173 ft · 29 sec
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9
Keep slight right to continue on Rolesville Road
94 m · 8 sec
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10
Turn right onto Rolesville Road
2.4 mi · 4 min · Rolesville Road
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11
Turn sharp left onto Marks Creek Road
2050 ft · 39 sec · Marks Creek Road
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12
Turn right onto Horton Road
2310 ft · 44 sec · Horton Road
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13
Turn right onto Buffaloe Road
3.8 mi · 7 min · Buffaloe Road
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14
Take the ramp right
1943 ft · 24 sec
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15
Merge slight left onto Northern Wake Expressway
15.4 mi · 17 min · Northern Wake Expressway
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16
Take the exit slight right toward US 70 West: Durham
2972 ft · 1 min
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17
Merge slight left onto Glenwood Avenue
1.9 mi · 3 min · Glenwood Avenue
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18
Continue on New Raleigh Highway
2.5 mi · 4 min · New Raleigh Highway
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19
Continue on South Miami Boulevard
9.3 mi · 12 min · South Miami Boulevard
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20
Keep slight left
42.3 mi · 49 min
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21
Keep slight right
7.7 mi · 9 min
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22
Keep slight right
12.6 mi · 15 min
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23
Keep slight right to continue on Salem Parkway
13.4 mi · 16 min · Salem Parkway
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24
Take the exit slight right toward Main Street
1174 ft · 29 sec
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25
Turn slight right onto South Main Street
2161 ft · 44 sec · South Main Street
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26
Arrive at your destination
0 m · 1 sec · North Main Street
Car Route Details
A richer read on the saved driving route between Manteo and Winston-Salem.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
N US Highway 64
Keep slight left
67.3 mi · 01h 27m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Showers And Thunderstorms Likely leaving Manteo and Mostly Sunny near Winston-Salem.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Manteo to Winston-Salem?
The road trip is about 292.4 miles (470.6 km) and usually takes 04h 38m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Nashville is a useful midpoint, sitting about 143.4 miles from Manteo and 148.9 miles from Winston-Salem.
How much longer is the road route than the straight-line distance?
The direct path is about 255.7 miles (411.5 km), while the road route adds roughly 36.7 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 7:44 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $40.88 one way or $81.76 round trip. Estimated CO2 is about 91.7 kg one way.
What should you check before leaving?
Before you leave, expect Showers And Thunderstorms Likely around Manteo and Mostly Sunny near Winston-Salem.
Stop Ideas Near Nashville
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Nashville.
Rocky Mount
Wilson
Selma–Smithfield
Raleigh Union Station
Flight Path Map
This map shows the direct air route between Manteo and Winston-Salem. Straight-line distance: 255.68 mi (411.47 km).
#1 Manteo
Town in Dare County, North Carolina, United States
| Population | 1,468 |
| Coordinates | 35.9082300, -75.6757300 |
| Altitude | 2 |
| Country | United States |
#2 Winston-Salem
The fifth most populous city in North Carolina.
| Population | 248,112 |
| Coordinates | 36.0998600, -80.2442200 |
| Altitude | 293 |
| Country | United States |
End: North Main Street (-80.244255, 36.099856)
Estimated Travel Time
Distance: 471 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 09h 44m |
| 40 mph (64.37 km/h) | 07h 18m |
| 50 mph (80.47 km/h) | 05h 50m |
| 60 mph (96.56 km/h) | 04h 52m |
| 70 mph (112.65 km/h) | 04h 10m |
| 80 mph (129 km/h) | 03h 38m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.96 | $40.88 | $81.76 |
| Mid-grade | $4.43 | $45.71 | $91.41 |
| Premium | $4.78 | $49.31 | $98.62 |
| Diesel | $5.62 | $58.04 | $116.08 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in North Carolina · May 31, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.