How far is Manchester, MO from Cape Girardeau, MO?
The driving distance from Manchester, MO to Cape Girardeau, MO is about 120.2 miles (193.5 km), with a travel time of about 01h 52m by car.
- The straight-line flight distance is about 104.3 miles (167.8 km).
- For a round trip, plan for roughly 03h 45m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM CDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 01h 52m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in and the county seat of Ste.
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Driving Route Map
The map below follows the saved road route between Manchester and Cape Girardeau.
Turn-by-Turn Driving Directions
Step-by-step road directions between Manchester and Cape Girardeau.
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1
Start on Woods Mill Road
627 ft · 28 sec · Woods Mill Road
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2
Take the ramp right toward MO 141 South
60 m · 5 sec
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3
Merge slight left
7.9 mi · 13 min
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4
Keep slight left
7.1 mi · 10 min
-
5
Take the exit slight right toward I 55 South
1073 ft · 27 sec
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6
Merge slight left
91.6 mi · 1 hr 38 min
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7
Take the exit slight right toward US 61, MO 34, I 55 Business: Cape Girardeau, Jackson
814 ft · 17 sec
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8
Keep slight left to continue on I 55 Business, US 61 South, MO 34 East: Cape Girardeau
1354 ft · 29 sec
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9
Continue on North Kingshighway
3.6 mi · 6 min · North Kingshighway
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10
Turn left onto Broadway Street
2 mi · 4 min · Broadway Street
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11
Arrive at your destination
0 m · 1 sec · Broadway Street
Car Route Details
A richer read on the saved driving route between Manchester and Cape Girardeau.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 55 South
Merge slight left
91.6 mi · 01h 38m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Sunny leaving Manchester and Sunny near Cape Girardeau.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Manchester to Cape Girardeau?
The road trip is about 120.2 miles (193.5 km) and usually takes 01h 52m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Sainte Genevieve is a useful midpoint, sitting about 56.5 miles from Manchester and 63.7 miles from Cape Girardeau.
How much longer is the road route than the straight-line distance?
The direct path is about 104.3 miles (167.8 km), while the road route adds roughly 15.9 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM CDT. If you want a more comfortable same-day return, try to leave by 2:44 PM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $15.99 one way or $31.98 round trip. Estimated CO2 is about 37.7 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Manchester and Sunny near Cape Girardeau.
Stop Ideas Near Sainte Genevieve
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Sainte Genevieve.
Du Quoin
Gateway Transportation Center
Kirkwood
Carbondale station
Flight Path Map
This map shows the direct air route between Manchester and Cape Girardeau. Straight-line distance: 104.28 mi (167.82 km).
#1 Manchester
City in Missouri
| Population | 18,081 |
| Coordinates | 38.5970000, -90.5092900 |
| Altitude | 176 |
| Country | United States |
#2 Cape Girardeau
The second-largest city in Cape Girardeau County, Missouri.
| Population | 41,588 |
| Coordinates | 37.3058800, -89.5181500 |
| Altitude | 108 |
| Country | United States |
End: Broadway Street (-89.518146, 37.305904)
Estimated Travel Time
Distance: 194 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 04h 00m |
| 40 mph (64.37 km/h) | 03h 00m |
| 50 mph (80.47 km/h) | 02h 24m |
| 60 mph (96.56 km/h) | 02h 00m |
| 70 mph (112.65 km/h) | 01h 43m |
| 80 mph (129 km/h) | 01h 30m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $15.99 | $31.98 |
| Mid-grade | $4.25 | $18.03 | $36.07 |
| Premium | $4.65 | $19.73 | $39.47 |
| Diesel | $5.30 | $22.49 | $44.98 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · May 12, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.