How far is Macon, MO from St. Louis, MO?
The driving distance from Macon, MO to St. Louis, MO is about 179.6 miles (289 km), with a travel time of about 02h 44m by car.
- The straight-line flight distance is about 144.2 miles (232 km).
- For a round trip, plan for roughly 05h 28m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM CDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 02h 44m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Missouri, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Showers And Thunderstorms
Mostly Sunny
Driving Route Map
The map below follows the saved road route between Macon and St. Louis.
Turn-by-Turn Driving Directions
Step-by-step road directions between Macon and St. Louis.
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1
Start on Walker Street
48 m · 8 sec · Walker Street
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2
Turn right onto East Washington Street
47 m · 12 sec · East Washington Street
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3
Turn left onto North Rollins Street
1.3 mi · 3 min · North Rollins Street
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4
At the end of the road, turn right onto South Missouri Street
55.5 mi · 1 hr · South Missouri Street
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5
Take the exit slight right toward MO PP, I 70, US 40: Kansas City, Saint Louis
2467 ft · 56 sec
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6
Turn straight
2352 ft · 55 sec
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7
Take the exit left toward I 70 East, US 40 East: Saint Louis
1271 ft · 31 sec
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8
Continue on Dwight D. Eisenhower Highway
81 mi · 1 hr 35 min · Dwight D. Eisenhower Highway
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9
Take the exit slight right toward I 64 East, US 40 East, US 61 South: Chesterfield
1567 ft · 33 sec
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10
Merge slight left onto Avenue of the Saints
27.7 mi · 34 min · Avenue of the Saints
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11
Continue on Daniel Boone Expressway
5.7 mi · 7 min · Daniel Boone Expressway
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12
Continue on Jack Buck Memorial Highway
5.8 mi · 7 min · Jack Buck Memorial Highway
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13
Take the exit slight right toward 14th Street
1115 ft · 34 sec
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14
Turn left onto South 14th Street
1715 ft · 42 sec · South 14th Street
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15
Turn right onto Market Street
956 ft · 25 sec · Market Street
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16
Arrive at your destination
0 m · 1 sec · Market Street
Car Route Details
A richer read on the saved driving route between Macon and St. Louis.
Interchange-aware route
The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.
Dwight D. Eisenhower Highway
Continue on Dwight D. Eisenhower Highway
81 mi · 01h 35m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Chance Showers And Thunderstorms leaving Macon and Mostly Sunny near St. Louis.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Macon to St. Louis?
The road trip is about 179.6 miles (289 km) and usually takes 02h 44m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Montgomery City is a useful midpoint, sitting about 89.5 miles from Macon and 90 miles from St. Louis.
How much longer is the road route than the straight-line distance?
The direct path is about 144.2 miles (232 km), while the road route adds roughly 35.4 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM CDT. If you want a more comfortable same-day return, try to leave by 1:02 PM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $23.91 one way or $47.82 round trip. Estimated CO2 is about 56.3 kg one way.
What should you check before leaving?
Before you leave, expect Chance Showers And Thunderstorms around Macon and Mostly Sunny near St. Louis.
Stop Ideas Near Montgomery City
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Montgomery City.
Hermann
Washington
Jefferson City
Kirkwood
Flight Path Map
This map shows the direct air route between Macon and St. Louis. Straight-line distance: 144.13 mi (231.96 km).
#1 Macon
City in Missouri, United States of America
| Population | 5,341 |
| Coordinates | 39.7422600, -92.4726900 |
| Altitude | 265 |
| Country | United States |
#2 St. Louis
The second most populous city in Missouri and the center of the St.
| Population | 315,685 |
| Coordinates | 38.6272700, -90.1978900 |
| Altitude | 142 |
| Country | United States |
End: Market Street (-90.197859, 38.627348)
Estimated Travel Time
Distance: 289 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 05h 58m |
| 40 mph (64.37 km/h) | 04h 29m |
| 50 mph (80.47 km/h) | 03h 35m |
| 60 mph (96.56 km/h) | 02h 59m |
| 70 mph (112.65 km/h) | 02h 33m |
| 80 mph (129 km/h) | 02h 14m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $23.91 | $47.82 |
| Mid-grade | $4.25 | $26.96 | $53.93 |
| Premium | $4.65 | $29.51 | $59.01 |
| Diesel | $5.30 | $33.63 | $67.25 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.