How far is Louisburg, NC from Winston-Salem, NC?
The driving distance from Louisburg, NC to Winston-Salem, NC is about 120.1 miles (193.3 km), with a travel time of about 02h 07m by car.
- The straight-line flight distance is about 108.5 miles (174.6 km).
- For a round trip, plan for roughly 04h 14m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM EDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 02h 07m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Alamance County, North Carolina, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Driving Route Map
The map below follows the saved road route between Louisburg and Winston-Salem.
Turn-by-Turn Driving Directions
Step-by-step road directions between Louisburg and Winston-Salem.
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1
Start on West Nash Street
13 m · 6 sec · West Nash Street
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2
Turn right onto South Main Street
1.3 mi · 2 min · South Main Street
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3
At the end of the road, turn right
15.8 mi · 25 min
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4
Continue straight
70 m · 7 sec
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5
Continue straight
6.7 mi · 12 min
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6
Turn left onto North Durham Avenue
5.5 mi · 9 min · North Durham Avenue
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7
Take the ramp left
11.7 mi · 14 min
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8
Keep slight left
42.3 mi · 49 min
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9
Keep slight right
7.7 mi · 9 min
-
10
Keep slight right
12.6 mi · 15 min
-
11
Keep slight right to continue on Salem Parkway
13.4 mi · 16 min · Salem Parkway
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12
Take the exit slight right toward Main Street
1174 ft · 29 sec
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13
Turn slight right onto South Main Street
2161 ft · 44 sec · South Main Street
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14
Arrive at your destination
0 m · 1 sec · North Main Street
Car Route Details
A richer read on the saved driving route between Louisburg and Winston-Salem.
Straightforward drive
The saved road route has a manageable number of maneuvers and should be easy to follow with normal attention to signs.
North Durham Avenue
Keep slight left
42.3 mi · 00h 49m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Sunny leaving Louisburg and Mostly Sunny near Winston-Salem.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Louisburg to Winston-Salem?
The road trip is about 120.1 miles (193.3 km) and usually takes 02h 07m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Mebane is a useful midpoint, sitting about 58.8 miles from Louisburg and 61.3 miles from Winston-Salem.
How much longer is the road route than the straight-line distance?
The direct path is about 108.5 miles (174.6 km), while the road route adds roughly 11.6 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM EDT. If you want a more comfortable same-day return, try to leave by 2:16 PM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $16.79 one way or $33.59 round trip. Estimated CO2 is about 37.7 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Louisburg and Mostly Sunny near Winston-Salem.
Stop Ideas Near Mebane
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Burlington City Switchboard
Carrboro Town Hall
Burlington Tax Department
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Mebane.
Burlington
Durham
J. Douglas Galyon Depot
Danville
Flight Path Map
This map shows the direct air route between Louisburg and Winston-Salem. Straight-line distance: 108.48 mi (174.58 km).
#1 Louisburg
Town in Franklin County, North Carolina
| Population | 3,694 |
| Coordinates | 36.0990400, -78.3011100 |
| Altitude | 67 |
| Country | United States |
#2 Winston-Salem
The fifth most populous city in North Carolina.
| Population | 248,112 |
| Coordinates | 36.0998600, -80.2442200 |
| Altitude | 293 |
| Country | United States |
End: North Main Street (-80.244255, 36.099856)
Estimated Travel Time
Distance: 193 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 04h 00m |
| 40 mph (64.37 km/h) | 03h 00m |
| 50 mph (80.47 km/h) | 02h 24m |
| 60 mph (96.56 km/h) | 02h 00m |
| 70 mph (112.65 km/h) | 01h 42m |
| 80 mph (129 km/h) | 01h 29m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.96 | $16.79 | $33.59 |
| Mid-grade | $4.43 | $18.78 | $37.56 |
| Premium | $4.78 | $20.26 | $40.52 |
| Diesel | $5.62 | $23.85 | $47.69 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in North Carolina · Apr 19, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.