How far is Lisle, NY from Buffalo, NY?
The driving distance from Lisle, NY to Buffalo, NY is about 202.8 miles (326.3 km), with a travel time of about 03h 15m by car.
- The straight-line flight distance is about 150.8 miles (242.7 km).
- For a round trip, plan for roughly 06h 31m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 15m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Village in Ontario County, New York, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Showers And Thunderstorms
Chance T-storms then Rain
Driving Route Map
The map below follows the saved road route between Lisle and Buffalo.
Turn-by-Turn Driving Directions
Step-by-step road directions between Lisle and Buffalo.
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1
Start on Main Street
2898 ft · 37 sec · Main Street
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2
Continue on State Highway 79
15.2 mi · 17 min · State Highway 79
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3
Continue on Slaterville Road
11.1 mi · 17 min · Slaterville Road
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4
Continue on East State Street
1.1 mi · 2 min · East State Street
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5
Keep slight right to continue on Seneca Way
678 ft · 19 sec · Seneca Way
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6
Continue on East Seneca Street
1.4 km · 2 min · East Seneca Street
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7
Turn right onto Taughannock Boulevard
103 m · 15 sec · Taughannock Boulevard
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8
Turn left onto West Buffalo Street
871 ft · 21 sec · West Buffalo Street
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9
Continue on Cliff Street
1.5 km · 2 min · Cliff Street
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10
Continue on Trumansburg Road
8.7 mi · 13 min · Trumansburg Road
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11
Continue on East Main Street
1.4 mi · 2 min · East Main Street
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12
Continue on Trumansburg Road
704 ft · 12 sec · Trumansburg Road
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13
Continue on State Highway 96
4 mi · 6 min · State Highway 96
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14
Turn right onto Powell Road
1.5 mi · 2 min · Powell Road
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15
Continue on County Road 141
1.4 km · 1 min · County Road 141
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16
Turn left onto State Highway 89
10.1 mi · 14 min · State Highway 89
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17
Turn left onto Ernsberger Road
2.4 mi · 4 min · Ernsberger Road
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18
At the end of the road, turn right onto Ovid Street
2.8 mi · 4 min · Ovid Street
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19
Turn left onto Townline Road
1.8 mi · 3 min · Townline Road
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20
Turn right onto State Highway 96
6.2 mi · 9 min · State Highway 96
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21
Continue on Fayette Street
1281 ft · 37 sec · Fayette Street
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22
Turn right onto West River Street
108 m · 16 sec · West River Street
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23
Turn left onto Washington Street
1639 ft · 28 sec · Washington Street
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24
Continue on South Virginia Street
1.4 km · 1 min · South Virginia Street
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25
Turn left onto North Road
906 ft · 15 sec · North Road
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26
Continue on State Highway 96
6 mi · 9 min · State Highway 96
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27
Take the ramp slight right toward I 90: Lyons, Thruway
1447 ft · 40 sec
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28
Merge slight left
942 ft · 20 sec
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29
Take the exit left
773 ft · 19 sec
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30
Keep slight left to continue on I 90 West: Buffalo
2379 ft · 58 sec
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31
Continue on I 90 West: Buffalo
1219 ft · 30 sec
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32
Merge slight left onto New York State Thruway
93.7 mi · 1 hr 49 min · New York State Thruway
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33
Take the exit slight right toward NY 33 West: Buffalo
1901 ft · 46 sec
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34
Merge slight left onto Kensington Expressway
6.4 mi · 9 min · Kensington Expressway
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35
Keep slight left to continue on Oak Street
2170 ft · 40 sec
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36
Continue on Oak Street
131 m · 14 sec · Oak Street
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37
Turn right onto Genesee Street
1172 ft · 39 sec · Genesee Street
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38
Turn right onto East Huron Street
729 ft · 34 sec · East Huron Street
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39
Turn left onto Franklin Street
716 ft · 23 sec · Franklin Street
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40
Turn right onto Genesee Street
123 m · 12 sec · Genesee Street
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41
Enter the roundabout toward Niagara Square
119 m · 12 sec · Niagara Square
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42
Arrive at your destination
0 m · 1 sec · Niagara Square
Car Route Details
A richer read on the saved driving route between Lisle and Buffalo.
Interchange-aware route
The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.
New York State Thruway
Merge slight left onto New York State Thruway
93.7 mi · 01h 49m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Showers And Thunderstorms leaving Lisle and Chance T-storms then Rain near Buffalo.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Lisle to Buffalo?
The road trip is about 202.8 miles (326.3 km) and usually takes 03h 15m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Manchester is a useful midpoint, sitting about 90.2 miles from Lisle and 112.6 miles from Buffalo.
How much longer is the road route than the straight-line distance?
The direct path is about 150.8 miles (242.7 km), while the road route adds roughly 52 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 10:28 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $31.80 one way or $63.61 round trip. Estimated CO2 is about 63.5 kg one way.
What should you check before leaving?
Before you leave, expect Showers And Thunderstorms around Lisle and Chance T-storms then Rain near Buffalo.
Stop Ideas Near Manchester
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Manchester.
Louise M. Slaughter Rochester Station
Empire Expo Center
William F. Walsh Regional Transportation Center
Flight Path Map
This map shows the direct air route between Lisle and Buffalo. Straight-line distance: 150.78 mi (242.66 km).
#1 Lisle
City in Broome County, New York, United States of America
| Population | 294 |
| Coordinates | 42.3511800, -76.0032600 |
| Altitude | 297 |
| Country | United States |
#2 Buffalo
The second most populous city in New York.
| Population | 254,479 |
| Coordinates | 42.8864500, -78.8783700 |
| Altitude | 183 |
| Country | United States |
End: Niagara Square (-78.878786, 42.886515)
Estimated Travel Time
Distance: 326 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 06h 45m |
| 40 mph (64.37 km/h) | 05h 04m |
| 50 mph (80.47 km/h) | 04h 03m |
| 60 mph (96.56 km/h) | 03h 22m |
| 70 mph (112.65 km/h) | 02h 53m |
| 80 mph (129 km/h) | 02h 31m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.45 | $31.80 | $63.61 |
| Mid-grade | $4.98 | $35.62 | $71.24 |
| Premium | $5.38 | $38.48 | $76.96 |
| Diesel | $6.51 | $46.54 | $93.08 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in New York · Oct 15, 2026