How far is Laredo, TX from Brenham, TX?
The driving distance from Laredo, TX to Brenham, TX is about 302.5 miles (486.9 km), with a travel time of about 05h 33m by car.
- The straight-line flight distance is about 263.1 miles (423.4 km).
- For a round trip, plan for roughly 11h 06m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 33m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
The seventh most populous city in the United States and the center of the San Antonio metropolitan area.
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Laredo and Brenham.
Turn-by-Turn Driving Directions
Step-by-step road directions between Laredo and Brenham.
-
1
Start on Matamoros Street
1544 ft · 46 sec · Matamoros Street
-
2
Turn left onto San Dario Avenue
553 ft · 11 sec · San Dario Avenue
-
3
Continue on Purple Heart Trail
144.4 mi · 2 hr 27 min · Purple Heart Trail
-
4
Continue on South Pan Am Expressway
8.4 mi · 10 min · South Pan Am Expressway
-
5
Take the exit slight right toward I 10 East, US 90 West, US 90 East, US 87 South: Houston, Del Rio
616 ft · 15 sec
-
6
Keep slight right to continue on I 10 East, US 90 East, US 87 South: Houston
2146 ft · 52 sec
-
7
Merge slight left onto Jose Lopez Freeway
8 mi · 9 min · Jose Lopez Freeway
-
8
Continue on 90th Infantry Division Highway
22.2 mi · 23 min · 90th Infantry Division Highway
-
9
Continue on I 10 East: Houston, Austin, Waco
58.3 mi · 58 min
-
10
Take the exit slight right toward TX 95, FM 609: Flatonia, Smithville
1494 ft · 21 sec
-
11
Continue on East Interstate 10 Frontage Road
1956 ft · 57 sec · East Interstate 10 Frontage Road
-
12
Turn left
19.5 mi · 27 min
-
13
At the end of the road, turn right onto West Travis Street
2.6 mi · 4 min · West Travis Street
-
14
Turn left onto East State Highway 159
6.6 mi · 10 min · East State Highway 159
-
15
Continue straight
15.6 mi · 23 min
-
16
Turn left
149 m · 27 sec
-
17
Turn sharp right onto US Highway 290 West
13.7 mi · 15 min · US Highway 290 West
-
18
Continue on West Main Street
1.6 mi · 3 min · West Main Street
-
19
Arrive at your destination
0 m · 1 sec · East Alamo Street
Car Route Details
A richer read on the saved driving route between Laredo and Brenham.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Purple Heart Trail
Continue on Purple Heart Trail
144 mi · 02h 27m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Partly Sunny leaving Laredo and Chance Showers And Thunderstorms near Brenham.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Laredo to Brenham?
The road trip is about 302.5 miles (486.9 km) and usually takes 05h 33m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
San Antonio is a useful midpoint, sitting about 151.4 miles from Laredo and 151.2 miles from Brenham.
How much longer is the road route than the straight-line distance?
The direct path is about 263.1 miles (423.4 km), while the road route adds roughly 39.4 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 5:54 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $40.36 one way or $80.72 round trip. Estimated CO2 is about 94.9 kg one way.
What should you check before leaving?
Before you leave, expect Partly Sunny around Laredo and Chance Showers And Thunderstorms near Brenham.
Stop Ideas Near San Antonio
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Piazza Italia Park
City Hall San Antonio
Municipal Plaza
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to San Antonio.
San Antonio Station
San Marcos Station
Austin
Flight Path Map
This map shows the direct air route between Laredo and Brenham. Straight-line distance: 263.06 mi (423.36 km).
#1 Laredo
The third most populous city in Texas and the center of the Laredo metropolitan area.
| Population | 263,640 |
| Coordinates | 27.5064100, -99.5075400 |
| Altitude | 126 |
| Country | United States |
#2 Brenham
City in Texas
| Population | 17,736 |
| Coordinates | 30.1668800, -96.3977400 |
| Altitude | 104 |
| Country | United States |
End: Brenham (-96.39774, 30.16688)
Estimated Travel Time
Distance: 487 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 10h 04m |
| 40 mph (64.37 km/h) | 07h 33m |
| 50 mph (80.47 km/h) | 06h 03m |
| 60 mph (96.56 km/h) | 05h 02m |
| 70 mph (112.65 km/h) | 04h 19m |
| 80 mph (129 km/h) | 03h 46m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.78 | $40.36 | $80.72 |
| Mid-grade | $4.25 | $45.41 | $90.82 |
| Premium | $4.59 | $49.03 | $98.06 |
| Diesel | $3.99 | $42.65 | $85.29 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Texas · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.