How far is Jefferson City, MO from De Soto, MO?
The driving distance from Jefferson City, MO to De Soto, MO is about 121.5 miles (195.6 km), with a travel time of about 02h 53m by car.
- The straight-line flight distance is about 92.7 miles (149.2 km).
- For a round trip, plan for roughly 05h 47m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM CDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 02h 53m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Village in Missouri, USA
Route Weather Snapshot
Check the forecast at both ends before you head out.
Scattered Showers And Thunderstorms then Chance Showers And Thunderstorms
Chance Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Jefferson City and De Soto.
Turn-by-Turn Driving Directions
Step-by-step road directions between Jefferson City and De Soto.
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1
Start on East Wall Way
47 m · 13 sec · East Wall Way
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2
Turn right onto Jefferson Street
1130 ft · 40 sec · Jefferson Street
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3
Turn left onto Rex M Whitton Expressway
11.3 mi · 14 min · Rex M Whitton Expressway
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4
Keep slight left to continue on US 50 East: Saint Louis
5.9 mi · 7 min
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5
Turn left onto Wolf Ridge Trail
1995 ft · 2 min · Wolf Ridge Trail
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6
At the end of the road, turn right onto Loose Creek Highway
1 mi · 2 min · Loose Creek Highway
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7
Continue on County Route 604
1 km · 3 min · County Route 604
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8
Turn left onto County Route 605
1.5 mi · 6 min · County Route 605
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9
Turn left
1817 ft · 36 sec
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10
Continue on West Main Street
56.6 mi · 1 hr 6 min · West Main Street
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11
Take the exit right
42 m · 5 sec
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12
Turn right
6.2 mi · 9 min
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13
Turn right onto Commercial Avenue
1 mi · 2 min · Commercial Avenue
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14
Continue on East Gravois Avenue
16 mi · 23 min · East Gravois Avenue
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15
Turn right onto Ridge Road
4 mi · 10 min · Ridge Road
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16
At the end of the road, turn right
9.5 mi · 19 min
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17
Continue straight
3.9 mi · 5 min
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18
Turn left
1.5 mi · 2 min
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19
Turn right onto North Main Street
1.4 mi · 2 min · North Main Street
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20
Turn right onto Easton Street
133 m · 19 sec · Easton Street
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21
Arrive at your destination
0 m · 1 sec · Easton Street
Car Route Details
A richer read on the saved driving route between Jefferson City and De Soto.
Straightforward drive
The saved road route has a manageable number of maneuvers and should be easy to follow with normal attention to signs.
West Main Street
Continue on West Main Street
56.6 mi · 01h 06m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Scattered Showers And Thunderstorms then Chance Showers And Thunderstorms leaving Jefferson City and Chance Showers And Thunderstorms near De Soto.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Jefferson City to De Soto?
The road trip is about 121.5 miles (195.6 km) and usually takes 02h 53m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Leslie is a useful midpoint, sitting about 60.7 miles from Jefferson City and 60.8 miles from De Soto.
How much longer is the road route than the straight-line distance?
The direct path is about 92.7 miles (149.2 km), while the road route adds roughly 28.8 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM CDT. If you want a more comfortable same-day return, try to leave by 12:42 PM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $16.18 one way or $32.36 round trip. Estimated CO2 is about 38.1 kg one way.
What should you check before leaving?
Before you leave, expect Scattered Showers And Thunderstorms then Chance Showers And Thunderstorms around Jefferson City and Chance Showers And Thunderstorms near De Soto.
Stop Ideas Near Leslie
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Leslie.
Washington
Hermann
Kirkwood
Jefferson City
Flight Path Map
This map shows the direct air route between Jefferson City and De Soto. Straight-line distance: 92.74 mi (149.25 km).
#1 Jefferson City
The capital of Missouri.
| Population | 42,708 |
| Coordinates | 38.5767000, -92.1735200 |
| Altitude | 192 |
| Country | United States |
#2 De Soto
City in Jefferson County, Missouri
| Population | 6,340 |
| Coordinates | 38.1395000, -90.5551300 |
| Altitude | 160 |
| Country | United States |
End: De Soto (-90.55513, 38.1395)
Estimated Travel Time
Distance: 196 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 04h 02m |
| 40 mph (64.37 km/h) | 03h 02m |
| 50 mph (80.47 km/h) | 02h 25m |
| 60 mph (96.56 km/h) | 02h 01m |
| 70 mph (112.65 km/h) | 01h 44m |
| 80 mph (129 km/h) | 01h 30m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $16.18 | $32.36 |
| Mid-grade | $4.25 | $18.25 | $36.49 |
| Premium | $4.65 | $19.97 | $39.93 |
| Diesel | $5.30 | $22.75 | $45.51 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · May 31, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.