How far is Irvine, CA from East Palo Alto, CA?
The driving distance from Irvine, CA to East Palo Alto, CA is about 400.4 miles (644.4 km), with a travel time of about 07h 32m by car.
- The straight-line flight distance is about 357.4 miles (575.2 km).
- For a round trip, plan for roughly 15h 04m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM PDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 07h 32m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Census-designated place in Kern County, California
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Sunny
Driving Route Map
The map below follows the saved road route between Irvine and East Palo Alto.
Turn-by-Turn Driving Directions
Step-by-step road directions between Irvine and East Palo Alto.
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1
Start on San Diego Freeway
1.4 mi · 2 min · San Diego Freeway
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2
Take the exit slight right toward University Drive, Jeffrey Road
1456 ft · 21 sec
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3
Turn left onto Jeffrey Road
951 ft · 22 sec · Jeffrey Road
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4
Take the ramp slight right toward I 405 North: Los Angeles
1228 ft · 18 sec
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5
Merge slight left onto San Diego Freeway
4.2 mi · 5 min · San Diego Freeway
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6
Take the exit slight right toward CA 55 South, CA 55 North: Freeway
1254 ft · 16 sec
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7
Keep slight right to continue on CA 55 North
2685 ft · 35 sec
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8
Merge slight left onto Costa Mesa Freeway
3.2 mi · 4 min · Costa Mesa Freeway
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9
Keep slight right to continue on Costa Mesa Freeway
2136 ft · 28 sec · Costa Mesa Freeway
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10
Take the exit slight right toward I 5 North: Santa Ana
1.1 km · 47 sec
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11
Merge slight left onto Santa Ana Freeway
2756 ft · 36 sec · Santa Ana Freeway
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12
Keep slight right to continue on Santa Ana Freeway
1.7 mi · 2 min · Santa Ana Freeway
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13
Keep slight right to continue on Santa Ana Freeway
9.4 mi · 11 min · Santa Ana Freeway
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14
Keep slight right to continue on Santa Ana Freeway
18 mi · 21 min · Santa Ana Freeway
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15
Keep slight right to continue on Golden State Freeway
25.5 mi · 30 min · Golden State Freeway
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16
Keep slight left to continue on Golden State Freeway
2.2 mi · 3 min · Golden State Freeway
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17
Keep slight right to continue on I 5 Truck North, CA 14 Truck
1.5 mi · 2 min
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18
Keep slight left
36.1 mi · 42 min
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19
Keep slight left to continue on Golden State Freeway
22.3 mi · 25 min · Golden State Freeway
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20
Keep slight right to continue on Westside Freeway
182.5 mi · 3 hr 16 min · Westside Freeway
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21
Take the exit slight right toward CA 152 West: Gilroy, Hollister, San Jose
1038 ft · 27 sec
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22
Continue straight
28.7 mi · 33 min
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23
Keep slight right
11.9 mi · 17 min
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24
Take the exit slight right toward US 101 North: San Jose
2466 ft · 1 min
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25
Merge slight left onto South Valley Freeway
19.9 mi · 23 min · South Valley Freeway
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26
Keep slight left
21.9 mi · 25 min
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27
Keep slight left
5.4 mi · 6 min
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28
Take the exit slight right toward Palo Alto, East Palo Alto
157 m · 13 sec
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29
Keep slight right to continue on University Avenue, East Palo Alto
1097 ft · 34 sec
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30
Turn left onto Donohoe Street
108 m · 14 sec · Donohoe Street
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31
Turn right onto University Avenue
2271 ft · 1 min · University Avenue
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32
Arrive at your destination
0 m · 1 sec · University Avenue
Car Route Details
A richer read on the saved driving route between Irvine and East Palo Alto.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Westside Freeway
Keep slight right to continue on Westside Freeway
183 mi · 03h 16m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Mostly Sunny leaving Irvine and Sunny near East Palo Alto.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Irvine to East Palo Alto?
The road trip is about 400.4 miles (644.4 km) and usually takes 07h 32m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Lost Hills is a useful midpoint, sitting about 200.3 miles from Irvine and 200.1 miles from East Palo Alto.
How much longer is the road route than the straight-line distance?
The direct path is about 357.4 miles (575.2 km), while the road route adds roughly 43 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM PDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $81.52 one way or $163.03 round trip. Estimated CO2 is about 125.6 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around Irvine and Sunny near East Palo Alto.
Stop Ideas Near Lost Hills
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Lost Hills.
Wasco station
Kettleman City, California
Corcoran station
Bakersfield
Flight Path Map
This map shows the direct air route between Irvine and East Palo Alto. Straight-line distance: 357.41 mi (575.19 km).
#1 Irvine
A city located in Orange County, California.
| Population | 283,700 |
| Coordinates | 33.6694600, -117.8231100 |
| Altitude | 17 |
| Country | United States |
#2 East Palo Alto
City in San Mateo County, California, United States
| Population | 29,059 |
| Coordinates | 37.4688300, -122.1410800 |
| Altitude | 6 |
| Country | United States |
End: East Palo Alto (-122.14108, 37.46883)
Estimated Travel Time
Distance: 644 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 13h 20m |
| 40 mph (64.37 km/h) | 10h 00m |
| 50 mph (80.47 km/h) | 08h 00m |
| 60 mph (96.56 km/h) | 06h 40m |
| 70 mph (112.65 km/h) | 05h 43m |
| 80 mph (129 km/h) | 04h 59m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $5.77 | $81.52 | $163.03 |
| Mid-grade | $6.07 | $85.71 | $171.43 |
| Premium | $6.24 | $88.21 | $176.43 |
| Diesel | $7.57 | $106.92 | $213.84 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in California · Apr 18, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.