How far is Holly Springs, MS from Greenville, MS?
The driving distance from Holly Springs, MS to Greenville, MS is about 186 miles (299.4 km), with a travel time of about 03h 37m by car.
- The straight-line flight distance is about 157.8 miles (254 km).
- For a round trip, plan for roughly 07h 15m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 37m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Town in Mississippi
Route Weather Snapshot
Check the forecast at both ends before you head out.
Patchy Fog then Chance Showers And Thunderstorms
Mostly Sunny then Chance Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Holly Springs and Greenville.
Turn-by-Turn Driving Directions
Step-by-step road directions between Holly Springs and Greenville.
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1
Start on Holly Springs Road
3166 ft · 2 min · Holly Springs Road
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2
Turn right onto John Dunaway Road
1.6 mi · 6 min · John Dunaway Road
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3
At the end of the road, turn right onto Ranch Road
2896 ft · 2 min · Ranch Road
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4
Turn sharp left
18.1 mi · 32 min
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5
Turn left onto Elliot Street
105 m · 22 sec · Elliot Street
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6
Turn left onto Jefferson Street
29 m · 5 sec · Jefferson Street
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7
Turn right onto Thomas E Jolly Drive
1.6 km · 3 min · Thomas E Jolly Drive
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8
Turn slight right onto MS 27
69 m · 9 sec
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9
Turn straight
35.7 mi · 49 min
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10
Enter the roundabout and take exit 2 toward the route
49 m · 3 sec
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11
Exit the roundabout
2.6 mi · 4 min
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12
Take the ramp slight right toward I 55 North, US 51 North
1780 ft · 43 sec
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13
Merge slight left
19.7 mi · 21 min
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14
Keep slight right
967 ft · 14 sec
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15
Take the exit slight left toward I 20 West, US 49 North: Vicksburg, Yazoo City
928 ft · 23 sec
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16
Keep slight left to continue on I 20 West, US 49 North: Vicksburg, Yazoo City
1221 ft · 30 sec
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17
Merge slight right
2.4 mi · 3 min
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18
Take the exit slight right toward I 220 North, I 49 North: North Jackson, Yazoo City
5.2 mi · 6 min
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19
Take the exit slight right toward US 49 North: Yazoo City
1360 ft · 33 sec
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20
Merge slight left onto Medgar Evers Boulevard
39.5 mi · 49 min · Medgar Evers Boulevard
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21
Take the exit slight right toward US 49W North, MS 3 South: Indianola, Vicksburg
46.7 mi · 57 min
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22
Turn left
2.4 mi · 3 min
-
23
Keep slight left
1876 ft · 29 sec
-
24
Keep slight left
13.1 mi · 16 min
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25
Turn right
9.2 mi · 14 min
-
26
Turn right onto South Main Street
1.4 km · 2 min · South Main Street
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27
Turn right onto South Broadway Street
3 m · 1 sec · South Broadway Street
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28
Arrive at your destination
0 m · 1 sec · South Broadway Street
Car Route Details
A richer read on the saved driving route between Holly Springs and Greenville.
Interchange-aware route
The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.
US 49W North
Take the exit slight right toward US 49W North, MS 3 South: Indianola, Vicksburg
46.7 mi · 00h 57m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Patchy Fog then Chance Showers And Thunderstorms leaving Holly Springs and Mostly Sunny then Chance Showers And Thunderstorms near Greenville.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Holly Springs to Greenville?
The road trip is about 186 miles (299.4 km) and usually takes 03h 37m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Flora is a useful midpoint, sitting about 100.5 miles from Holly Springs and 85.5 miles from Greenville.
How much longer is the road route than the straight-line distance?
The direct path is about 157.8 miles (254 km), while the road route adds roughly 28.2 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 9:44 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $24.84 one way or $49.69 round trip. Estimated CO2 is about 58.3 kg one way.
What should you check before leaving?
Before you leave, expect Patchy Fog then Chance Showers And Thunderstorms around Holly Springs and Mostly Sunny then Chance Showers And Thunderstorms near Greenville.
Stop Ideas Near Flora
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Flora.
Union Station
Yazoo City
Vicksburg, MS
Hazlehurst station
Flight Path Map
This map shows the direct air route between Holly Springs and Greenville. Straight-line distance: 157.81 mi (253.97 km).
#1 Holly Springs
City in and county seat of Marshall County, Mississippi, United States
| Population | 7,684 |
| Coordinates | 31.3157300, -89.9778600 |
| Altitude | 93 |
| Country | United States |
#2 Greenville
City in Washington County, Mississippi, United States
| Population | 28,315 |
| Coordinates | 33.4089800, -91.0597800 |
| Altitude | 40 |
| Country | United States |
End: Main Street (-91.0598, 33.408959)
Estimated Travel Time
Distance: 299 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 06h 11m |
| 40 mph (64.37 km/h) | 04h 39m |
| 50 mph (80.47 km/h) | 03h 43m |
| 60 mph (96.56 km/h) | 03h 06m |
| 70 mph (112.65 km/h) | 02h 39m |
| 80 mph (129 km/h) | 02h 19m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.79 | $24.84 | $49.69 |
| Mid-grade | $4.26 | $27.94 | $55.88 |
| Premium | $4.63 | $30.34 | $60.68 |
| Diesel | $5.42 | $35.52 | $71.04 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Mississippi · May 31, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.