How far is Hollister, MO from O'Fallon, MO?
The driving distance from Hollister, MO to O'Fallon, MO is about 251 miles (403.9 km), with a travel time of about 04h 06m by car.
- The straight-line flight distance is about 204.4 miles (329 km).
- For a round trip, plan for roughly 08h 13m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 06m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
This departure sits inside the recommended comfort window for the route.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Pulaski County, Missouri, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Showers And Thunderstorms Likely
Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Hollister and O'Fallon.
Turn-by-Turn Driving Directions
Step-by-step road directions between Hollister and O'Fallon.
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1
Start on Old Mill Road
120 m · 23 sec · Old Mill Road
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2
Turn left onto Esplanade Drive
118 m · 24 sec · Esplanade Drive
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3
Turn left onto South Business 65
1.2 mi · 3 min · South Business 65
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4
Enter the roundabout and take exit 3 toward US 65 Business, MO 76 West: Branson
114 m · 7 sec
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5
Exit the roundabout onto US 65 Business, MO 76 West: Branson
1.2 km · 2 min
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6
Continue on Veterans Boulevard
1889 ft · 46 sec · Veterans Boulevard
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7
Continue on Veterans Boulevard
46 m · 4 sec · Veterans Boulevard
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8
Enter the roundabout and take exit 3 toward Branson Landing Boulevard
88 m · 8 sec · Branson Landing Boulevard
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9
Exit the roundabout onto Branson Landing Boulevard
2409 ft · 58 sec · Branson Landing Boulevard
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10
Take the ramp straight toward US 65 North: Springfield
1192 ft · 29 sec
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11
Merge slight left onto American Legion Memorial Highway
7.7 mi · 9 min · American Legion Memorial Highway
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12
Continue on US Highway 65
12 mi · 14 min · US Highway 65
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13
Continue on American Legion Memorial Highway
10.9 mi · 13 min · American Legion Memorial Highway
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14
Continue on Schoolcraft Freeway
10.7 mi · 13 min · Schoolcraft Freeway
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15
Take the exit slight right toward I 44 East: Saint Louis
3203 ft · 55 sec
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16
Merge slight left
170.3 mi · 3 hr 3 min
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17
Take the exit slight right toward I 44 Business, MO 100 East: Gray Summit
970 ft · 28 sec
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18
Turn left onto Manchester Road
13.4 mi · 19 min · Manchester Road
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19
Take the exit slight right toward MO 109
1108 ft · 31 sec
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20
Enter the roundabout and take exit 3 toward the route
68 m · 4 sec
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21
Exit the roundabout
157 m · 11 sec
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22
Enter the roundabout and take exit 1 toward the route
30 m · 2 sec
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23
Exit the roundabout
2129 ft · 45 sec
-
24
Enter the roundabout and take exit 2 toward the route
29 m · 2 sec
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25
Exit the roundabout
4.3 mi · 7 min
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26
Enter the roundabout and take exit 2 toward South Eatherton Road
29 m · 1 sec · South Eatherton Road
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27
Exit the roundabout onto South Eatherton Road
2.4 mi · 5 min · South Eatherton Road
-
28
Continue on Olive Street Road
1.5 km · 2 min · Olive Street Road
-
29
Take the ramp left toward Chesterfield Airport Road
1.1 km · 1 min · Chesterfield Airport Road
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30
Merge slight left onto Avenue of the Saints
3.1 mi · 4 min · Avenue of the Saints
-
31
Take the exit slight right toward MO K: O'Fallon
100 m · 6 sec
-
32
Merge slight right onto North Outer Road
1650 ft · 31 sec · North Outer Road
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33
Continue on North Outer Road
946 ft · 18 sec · North Outer Road
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34
Turn right
3.3 mi · 5 min
-
35
Continue straight
1.5 mi · 3 min
-
36
Continue straight
1.6 mi · 3 min
-
37
Continue on South Main Street
3115 ft · 2 min · South Main Street
-
38
Turn right
8 m · 2 sec
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39
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between Hollister and O'Fallon.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 44 East
Merge slight left
170 mi · 03h 03m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Showers And Thunderstorms Likely leaving Hollister and Showers And Thunderstorms near O'Fallon.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Hollister to O'Fallon?
The road trip is about 251 miles (403.9 km) and usually takes 04h 06m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Saint Robert is a useful midpoint, sitting about 124.3 miles from Hollister and 126.7 miles from O'Fallon.
How much longer is the road route than the straight-line distance?
The direct path is about 204.4 miles (329 km), while the road route adds roughly 46.6 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 8:46 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $33.41 one way or $66.82 round trip. Estimated CO2 is about 78.7 kg one way.
What should you check before leaving?
Before you leave, expect Showers And Thunderstorms Likely around Hollister and Showers And Thunderstorms near O'Fallon.
Stop Ideas Near Saint Robert
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Saint Robert.
Jefferson City
Hermann
Flight Path Map
This map shows the direct air route between Hollister and O'Fallon. Straight-line distance: 204.41 mi (328.96 km).
#1 Hollister
City in Missouri
| Population | 4,607 |
| Coordinates | 36.6211700, -93.2154600 |
| Altitude | 220 |
| Country | United States |
#2 O'Fallon
The most populous city in St.
| Population | 89,769 |
| Coordinates | 38.8106100, -90.6998500 |
| Altitude | 165 |
| Country | United States |
End: (-90.699849, 38.810674)
Estimated Travel Time
Distance: 404 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 08h 21m |
| 40 mph (64.37 km/h) | 06h 16m |
| 50 mph (80.47 km/h) | 05h 01m |
| 60 mph (96.56 km/h) | 04h 10m |
| 70 mph (112.65 km/h) | 03h 35m |
| 80 mph (129 km/h) | 03h 07m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $33.41 | $66.82 |
| Mid-grade | $4.25 | $37.68 | $75.36 |
| Premium | $4.65 | $41.23 | $82.47 |
| Diesel | $5.30 | $46.99 | $93.99 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Apr 24, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.