How far is Hoffman Estates, IL from Murphysboro, IL?
The driving distance from Hoffman Estates, IL to Murphysboro, IL is about 353.2 miles (568.5 km), with a travel time of about 06h 46m by car.
- The straight-line flight distance is about 303 miles (487.6 km).
- For a round trip, plan for roughly 13h 33m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 06h 46m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Illinois
Route Weather Snapshot
Check the forecast at both ends before you head out.
Rain Showers
Showers And Thunderstorms Likely
Driving Route Map
The map below follows the saved road route between Hoffman Estates and Murphysboro.
Turn-by-Turn Driving Directions
Step-by-step road directions between Hoffman Estates and Murphysboro.
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1
Start on Bode Road
10 m · 9 sec · Bode Road
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2
Turn left onto North Roselle Road
532 ft · 11 sec · North Roselle Road
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3
Turn right onto West Higgins Road
2.5 mi · 5 min · West Higgins Road
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4
Turn right onto Frontage Road
611 ft · 20 sec · Frontage Road
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5
Take the ramp straight toward I 290 East, IL 53 South: Chicago
1185 ft · 29 sec
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6
Merge slight left
4.2 mi · 5 min
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7
Keep slight right to continue on I 290 East: Chicago
9.3 mi · 12 min
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8
Take the exit slight right toward I 88 West, I 294 South: Aurora, Indiana
1648 ft · 40 sec
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9
Continue on Tri-State Tollway
1937 ft · 47 sec · Tri-State Tollway
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10
Keep slight left to continue on Tri-State Tollway
1 mi · 2 min · Tri-State Tollway
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11
Merge slight left onto Tri-State Tollway
42 m · 2 sec · Tri-State Tollway
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12
Keep slight left to continue on Tri-State Tollway
4.8 mi · 6 min · Tri-State Tollway
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13
Keep slight right to continue on Tri-State Tollway
3.5 mi · 4 min · Tri-State Tollway
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14
Continue on Mile-Long Bridge
1.5 km · 1 min · Mile-Long Bridge
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15
Continue on Tri-State Tollway
8.5 mi · 11 min · Tri-State Tollway
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16
Take the exit slight right toward IL 50 South, IL 83: Cicero Avenue, 127th Street
1162 ft · 28 sec
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17
Keep slight left to continue on IL 50 South: Cicero Avenue
2529 ft · 1 min
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18
Turn straight onto Cicero Avenue
4.9 mi · 8 min · Cicero Avenue
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19
Turn left onto 167th Street
855 ft · 26 sec · 167th Street
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20
Take the ramp slight right toward I 57 South: Kankakee, I-80
3048 ft · 1 min
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21
Merge slight left
188.4 mi · 3 hr 24 min
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22
Keep slight left to continue on I 57 South: Memphis
65.7 mi · 1 hr 11 min
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23
Keep slight right to continue on Ken Gray Expressway
32.7 mi · 35 min · Ken Gray Expressway
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24
Take the exit slight right toward Johnston City, Herrin
1506 ft · 39 sec
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25
Turn right onto Herrin Road
3.1 mi · 5 min · Herrin Road
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26
Continue on East Herrin Street
3.1 mi · 5 min · East Herrin Street
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27
Continue on Herrin Road
3.5 mi · 5 min · Herrin Road
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28
Enter the roundabout and take exit 1 toward Cambria Road
11 m · 1 sec · Cambria Road
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29
Exit the roundabout onto Cambria Road
1.5 mi · 2 min · Cambria Road
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30
Turn left onto Russell Street
11.3 mi · 16 min · Russell Street
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31
Turn left onto North 2nd Street
1.4 km · 1 min · North 2nd Street
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32
Turn right onto Walnut Street
2911 ft · 1 min · Walnut Street
-
33
Turn right onto North 11th Street
20 m · 3 sec · North 11th Street
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34
Arrive at your destination
0 m · 1 sec · North 11th Street
Car Route Details
A richer read on the saved driving route between Hoffman Estates and Murphysboro.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
I 57 South
Merge slight left
188 mi · 03h 24m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Rain Showers leaving Hoffman Estates and Showers And Thunderstorms Likely near Murphysboro.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Hoffman Estates to Murphysboro?
The road trip is about 353.2 miles (568.5 km) and usually takes 06h 46m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Tuscola is a useful midpoint, sitting about 176.6 miles from Hoffman Estates and 176.7 miles from Murphysboro.
How much longer is the road route than the straight-line distance?
The direct path is about 303 miles (487.6 km), while the road route adds roughly 50.2 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM CDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $58.17 one way or $116.35 round trip. Estimated CO2 is about 110.8 kg one way.
What should you check before leaving?
Before you leave, expect Rain Showers around Hoffman Estates and Showers And Thunderstorms Likely near Murphysboro.
Stop Ideas Near Tuscola
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Tuscola.
Illinois Terminal
Mattoon station
Rantoul
Danville, Illinois
Flight Path Map
This map shows the direct air route between Hoffman Estates and Murphysboro. Straight-line distance: 302.99 mi (487.61 km).
#1 Hoffman Estates
A city in Cook County, Illinois.
| Population | 50,495 |
| Coordinates | 42.0428100, -88.0798000 |
| Altitude | 239 |
| Country | United States |
#2 Murphysboro
Town in Illinois
| Population | 7,384 |
| Coordinates | 37.7645000, -89.3350900 |
| Altitude | 128 |
| Country | United States |
End: Murphysboro (-89.33509, 37.7645)
Estimated Travel Time
Distance: 569 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 11h 46m |
| 40 mph (64.37 km/h) | 08h 49m |
| 50 mph (80.47 km/h) | 07h 03m |
| 60 mph (96.56 km/h) | 05h 53m |
| 70 mph (112.65 km/h) | 05h 02m |
| 80 mph (129 km/h) | 04h 24m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.67 | $58.17 | $116.35 |
| Mid-grade | $5.29 | $65.99 | $131.98 |
| Premium | $5.84 | $72.79 | $145.57 |
| Diesel | $6.57 | $81.94 | $163.88 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Illinois · Oct 15, 2026