How far is Henderson, KY from Maysville, KY?
The driving distance from Henderson, KY to Maysville, KY is about 263.5 miles (424.1 km), with a travel time of about 05h 11m by car.
- The straight-line flight distance is about 216 miles (347.6 km).
- For a round trip, plan for roughly 10h 22m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 11m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Human settlement in Jefferson County, Kentucky, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Partly Sunny
Driving Route Map
The map below follows the saved road route between Henderson and Maysville.
Turn-by-Turn Driving Directions
Step-by-step road directions between Henderson and Maysville.
-
1
Start on the route
30 m · 9 sec
-
2
Turn right onto Washington Street
65 m · 10 sec · Washington Street
-
3
Turn right onto South Green Street
1.6 mi · 4 min · South Green Street
-
4
Take the ramp straight toward US 41: Evansville, Madisonville
748 ft · 21 sec
-
5
Keep slight left to continue on US 41 North: Evansville
2451 ft · 1 min
-
6
Merge slight left
5.3 mi · 8 min
-
7
Take the exit slight right toward I 69 North
1008 ft · 17 sec
-
8
Keep slight right to continue on I 69 North
1.2 km · 1 min
-
9
Merge slight left
20 mi · 23 min
-
10
Take the exit slight right toward I 64 East: Louisville
3069 ft · 58 sec
-
11
Merge slight left
91.7 mi · 1 hr 40 min
-
12
Keep slight right
81.1 mi · 1 hr 32 min
-
13
Take the exit slight right toward US 27, US 68: Paris, Lexington
3139 ft · 1 min
-
14
Turn left onto North Broadway
2246 ft · 56 sec · North Broadway
-
15
Continue on Paris Pike
5.9 mi · 7 min · Paris Pike
-
16
Continue on Lexington Road
6.8 mi · 9 min · Lexington Road
-
17
Continue on Main Street
2.6 mi · 4 min · Main Street
-
18
Continue on Millersburg Road
6.9 mi · 8 min · Millersburg Road
-
19
Continue on Millersburg Bypass
2.1 mi · 2 min · Millersburg Bypass
-
20
Continue on US 68
2.2 mi · 2 min · US 68
-
21
Continue on Carlisle Bypass
3.9 mi · 5 min · Carlisle Bypass
-
22
Continue on Maysville Road
24.9 mi · 32 min · Maysville Road
-
23
Continue straight
1.7 mi · 3 min
-
24
Continue straight
2.9 mi · 5 min
-
25
Turn sharp right onto Forest Avenue
1.3 km · 1 min · Forest Avenue
-
26
Arrive at your destination
0 m · 1 sec · Forest Avenue
Car Route Details
A richer read on the saved driving route between Henderson and Maysville.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 64 East
Merge slight left
91.7 mi · 01h 40m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Mostly Sunny leaving Henderson and Partly Sunny near Maysville.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Henderson to Maysville?
The road trip is about 263.5 miles (424.1 km) and usually takes 05h 11m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Seneca Gardens is a useful midpoint, sitting about 131.6 miles from Henderson and 131.9 miles from Maysville.
How much longer is the road route than the straight-line distance?
The direct path is about 216 miles (347.6 km), while the road route adds roughly 47.5 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 6:38 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $35.07 one way or $70.14 round trip. Estimated CO2 is about 82.6 kg one way.
Do you cross a time zone on this route?
Yes. There is about a 1 hour time difference between Henderson and Maysville, so arrival and return times should be read in local time.
What should you check before leaving?
Before you leave, expect Mostly Sunny around Henderson and Partly Sunny near Maysville.
Stop Ideas Near Seneca Gardens
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Seneca Gardens.
Louisville, Kentucky
Flight Path Map
This map shows the direct air route between Henderson and Maysville. Straight-line distance: 215.96 mi (347.56 km).
#1 Henderson
City in and county seat of Henderson County, Kentucky, United States
| Population | 27,974 |
| Coordinates | 37.8361500, -87.5900100 |
| Altitude | 124 |
| Country | United States |
#2 Maysville
City in Mason County, Kentucky, United States
| Population | 8,683 |
| Coordinates | 38.6411900, -83.7443700 |
| Altitude | 165 |
| Country | United States |
End: Maysville (-83.74437, 38.64119)
Estimated Travel Time
Distance: 424 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 08h 46m |
| 40 mph (64.37 km/h) | 06h 35m |
| 50 mph (80.47 km/h) | 05h 16m |
| 60 mph (96.56 km/h) | 04h 23m |
| 70 mph (112.65 km/h) | 03h 45m |
| 80 mph (129 km/h) | 03h 17m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $35.07 | $70.14 |
| Mid-grade | $4.25 | $39.55 | $79.11 |
| Premium | $4.65 | $43.28 | $86.56 |
| Diesel | $5.30 | $49.33 | $98.65 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Kentucky · May 31, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.